Microbiology

  1. Number and proportion of P. falciparum gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rate

    1. Hannah van Dijk
    2. Martin Kampmann
    3. Nathalia F Lima
    4. Michael Gabel
    5. Usama Dabbas
    6. Safiatou Doumbo
    7. Hamidou Cisse
    8. Shanping Li
    9. Myriam Jeninga
    10. Richard Thomson-Luque
    11. Didier Doumtabe
    12. Michaela Petter
    13. Kassoum Kayentao
    14. Aissata Ongoiba
    15. Teun Bousema
    16. Peter D Crompton
    17. Boubacar Traore
    18. Frederik Graw
    19. Silvia Portugal

    • Curated by eLife

      Evaluation Summary:

      The work evaluates the production of P. falciparum sexual stage parasites in blood samples from asymptomatic parasite carriers through the dry season and symptomatic malaria patients in the wet season. Sexual stage parasites are required for malaria transmission via mosquito, but historically their low levels in peripheral blood have limited analysis. The work here monitored asexual and sexual stage parasitemia and found that the relative expression of early gametocyte genes, including ap2-g, is similar in samples from asymptomatic and asymptotic individuals. The data was used to model gametocyte availability from the initial symptomatic infection through the chronic phase and advances the understanding of factors that contribute to malaria transmission.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  2. SARS-CoV-2 Omicron Spike recognition by plasma from individuals receiving BNT162b2 mRNA vaccination with a 16-week interval between doses

    1. Debashree Chatterjee
    2. Alexandra Tauzin
    3. Lorie Marchitto
    4. Shang Yu Gong
    5. Marianne Boutin
    6. Catherine Bourassa
    7. Guillaume Beaudoin-Bussières
    8. Yuxia Bo
    9. Shilei Ding
    10. Annemarie Laumaea
    11. Dani Vézina
    12. Josée Perreault
    13. Laurie Gokool
    14. Chantal Morrisseau
    15. Pascale Arlotto
    16. Éric Fournier
    17. Aurélie Guilbault
    18. Benjamin Delisle
    19. Inès Levade
    20. Guillaume Goyette
    21. Gabrielle Gendron-Lepage
    22. Halima Medjahed
    23. Gaston De Serres
    24. Cécile Tremblay
    25. Valérie Martel-Laferrière
    26. Daniel E. Kaufmann
    27. Renée Bazin
    28. Jérémie Prévost
    29. Sandrine Moreira
    30. Jonathan Richard
    31. Marceline Côté
    32. Andrés Finzi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Construction of a potent pan-vaccine based on the evolutionary tendency of SARS-CoV-2 spike protein

    1. Yongliang Zhao
    2. Wenjia Ni
    3. Simeng Liang
    4. Lianghui Dong
    5. Min Xiang
    6. Zeng Cai
    7. Danping Niu
    8. Qiuhan Zhang
    9. Dehe Wang
    10. Yucheng Zheng
    11. Zhen Zhang
    12. Dan Zhou
    13. Wenhua Guo
    14. Yongbing Pan
    15. Xiaoli Wu
    16. Yimin Yang
    17. Zhaofei Jing
    18. Yongzhong Jiang
    19. SARS-CoV-2 Vaccine Task Force Group
    20. Yu Chen
    21. Huan Yan
    22. Yu Zhou
    23. Ke Xu
    24. Ke Lan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Nucleocapsid 203 mutations enhance SARS-CoV-2 immune evasion

    1. Xiaoyuan Lin
    2. Weiwei Xue
    3. Yueping Zhang
    4. Beibei Fu
    5. Jakob Trimpert
    6. Na Xing
    7. Dusan Kunec
    8. Wanyan Tang
    9. Yang Xiao
    10. Kaiwen Meng
    11. Shuobo Shi
    12. Haibo Wu
    13. Geng Meng
    14. Zhenglin Zhu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Efficacy of antiviral drugs against the omicron variant of SARS-CoV-2

    1. Agnieszka Dabrowska
    2. Artur Szczepanski
    3. Paweł Botwina
    4. Natalia Mazur-Panasiuk
    5. Helena Jiřincová
    6. Lukasz Rabalski
    7. Tomas Zajic
    8. Grzegorz Popowicz
    9. Krzysztof Pyrc

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

    1. Bo Meng
    2. Adam Abdullahi
    3. Isabella A. T. M. Ferreira
    4. Niluka Goonawardane
    5. Akatsuki Saito
    6. Izumi Kimura
    7. Daichi Yamasoba
    8. Pehuén Pereyra Gerber
    9. Saman Fatihi
    10. Surabhi Rathore
    11. Samantha K. Zepeda
    12. Guido Papa
    13. Steven A. Kemp
    14. Terumasa Ikeda
    15. Mako Toyoda
    16. Toong Seng Tan
    17. Jin Kuramochi
    18. Shigeki Mitsunaga
    19. Takamasa Ueno
    20. Kotaro Shirakawa
    21. Akifumi Takaori-Kondo
    22. Teresa Brevini
    23. Donna L. Mallery
    24. Oscar J. Charles
    25. The CITIID-NIHR BioResource COVID-19 Collaboration
    26. Stephen Baker
    27. Gordon Dougan
    28. Christoph Hess
    29. Nathalie Kingston
    30. Paul J. Lehner
    31. Paul A. Lyons
    32. Nicholas J. Matheson
    33. Willem H. Ouwehand
    34. Caroline Saunders
    35. Charlotte Summers
    36. James E. D. Thaventhiran
    37. Mark Toshner
    38. Michael P. Weekes
    39. Patrick Maxwell
    40. Ashley Shaw
    41. Ashlea Bucke
    42. Jo Calder
    43. Laura Canna
    44. Jason Domingo
    45. Anne Elmer
    46. Stewart Fuller
    47. Julie Harris
    48. Sarah Hewitt
    49. Jane Kennet
    50. Sherly Jose
    51. Jenny Kourampa
    52. Anne Meadows
    53. Criona O’Brien
    54. Jane Price
    55. Cherry Publico
    56. Rebecca Rastall
    57. Carla Ribeiro
    58. Jane Rowlands
    59. Valentina Ruffolo
    60. Hugo Tordesillas
    61. Ben Bullman
    62. Benjamin J. Dunmore
    63. Stefan Gräf
    64. Josh Hodgson
    65. Christopher Huang
    66. Kelvin Hunter
    67. Emma Jones
    68. Ekaterina Legchenko
    69. Cecilia Matara
    70. Jennifer Martin
    71. Federica Mescia
    72. Ciara O’Donnell
    73. Linda Pointon
    74. Joy Shih
    75. Rachel Sutcliffe
    76. Tobias Tilly
    77. Carmen Treacy
    78. Zhen Tong
    79. Jennifer Wood
    80. Marta Wylot
    81. Ariana Betancourt
    82. Georgie Bower
    83. Chiara Cossetti
    84. Aloka De Sa
    85. Madeline Epping
    86. Stuart Fawke
    87. Nick Gleadall
    88. Richard Grenfell
    89. Andrew Hinch
    90. Sarah Jackson
    91. Isobel Jarvis
    92. Ben Krishna
    93. Francesca Nice
    94. Ommar Omarjee
    95. Marianne Perera
    96. Martin Potts
    97. Nathan Richoz
    98. Veronika Romashova
    99. Luca Stefanucci
    100. Mateusz Strezlecki
    101. Lori Turner
    102. Eckart M. D. D. De Bie
    103. Katherine Bunclark
    104. Masa Josipovic
    105. Michael Mackay
    106. Helen Butcher
    107. Daniela Caputo
    108. Matt Chandler
    109. Patrick Chinnery
    110. Debbie Clapham-Riley
    111. Eleanor Dewhurst
    112. Christian Fernandez
    113. Anita Furlong
    114. Barbara Graves
    115. Jennifer Gray
    116. Sabine Hein
    117. Tasmin Ivers
    118. Emma Le Gresley
    119. Rachel Linger
    120. Mary Kasanicki
    121. Rebecca King
    122. Nathalie Kingston
    123. Sarah Meloy
    124. Alexei Moulton
    125. Francesca Muldoon
    126. Nigel Ovington
    127. Sofia Papadia
    128. Christopher J. Penkett
    129. Isabel Phelan
    130. Venkatesh Ranganath
    131. Roxana Paraschiv
    132. Abigail Sage
    133. Jennifer Sambrook
    134. Ingrid Scholtes
    135. Katherine Schon
    136. Hannah Stark
    137. Kathleen E. Stirrups
    138. Paul Townsend
    139. Neil Walker
    140. Jennifer Webster
    141. The Genotype to Phenotype Japan (G2P-Japan) Consortium
    142. Erika P. Butlertanaka
    143. Yuri L. Tanaka
    144. Jumpei Ito
    145. Keiya Uriu
    146. Yusuke Kosugi
    147. Mai Suganami
    148. Akiko Oide
    149. Miyabishara Yokoyama
    150. Mika Chiba
    151. Chihiro Motozono
    152. Hesham Nasser
    153. Ryo Shimizu
    154. Kazuko Kitazato
    155. Haruyo Hasebe
    156. Takashi Irie
    157. So Nakagawa
    158. Jiaqi Wu
    159. Miyoko Takahashi
    160. Takasuke Fukuhara
    161. Kenta Shimizu
    162. Kana Tsushima
    163. Haruko Kubo
    164. Yasuhiro Kazuma
    165. Ryosuke Nomura
    166. Yoshihito Horisawa
    167. Kayoko Nagata
    168. Yugo Kawai
    169. Yohei Yanagida
    170. Yusuke Tashiro
    171. Kenzo Tokunaga
    172. Seiya Ozono
    173. Ryoko Kawabata
    174. Nanami Morizako
    175. Kenji Sadamasu
    176. Hiroyuki Asakura
    177. Mami Nagashima
    178. Kazuhisa Yoshimura
    179. Ecuador-COVID19 Consortium
    180. Paúl Cárdenas
    181. Erika Muñoz
    182. Veronica Barragan
    183. Sully Márquez
    184. Belén Prado-Vivar
    185. Mónica Becerra-Wong
    186. Mateo Caravajal
    187. Gabriel Trueba
    188. Patricio Rojas-Silva
    189. Michelle Grunauer
    190. Bernardo Gutierrez
    191. Juan José Guadalupe
    192. Juan Carlos Fernández-Cadena
    193. Derly Andrade-Molina
    194. Manuel Baldeon
    195. Andrea Pinos
    196. John E. Bowen
    197. Anshu Joshi
    198. Alexandra C. Walls
    199. Laurelle Jackson
    200. Darren Martin
    201. Kenneth G. C. Smith
    202. John Bradley
    203. John A. G. Briggs
    204. Jinwook Choi
    205. Elo Madissoon
    206. Kerstin B. Meyer
    207. Petra Mlcochova
    208. Lourdes Ceron-Gutierrez
    209. Rainer Doffinger
    210. Sarah A. Teichmann
    211. Andrew J. Fisher
    212. Matteo S. Pizzuto
    213. Anna de Marco
    214. Davide Corti
    215. Myra Hosmillo
    216. Joo Hyeon Lee
    217. Leo C. James
    218. Lipi Thukral
    219. David Veesler
    220. Alex Sigal
    221. Fotios Sampaziotis
    222. Ian G. Goodfellow
    223. Nicholas J. Matheson
    224. Kei Sato
    225. Ravindra K. Gupta

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Neutralization against Omicron SARS-CoV-2 from previous non-Omicron infection

    1. Jing Zou
    2. Hongjie Xia
    3. Xuping Xie
    4. Chaitanya Kurhade
    5. Rafael R. G. Machado
    6. Scott C. Weaver
    7. Ping Ren
    8. Pei-Yong Shi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Structural flexibility of the SARS-CoV-2 genome relevant to variation, replication, pathogenicity, and immune evasion

    1. Roberto Patarca
    2. William A. Haseltine

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness

    1. Kyumin Kim
    2. Peter Calabrese
    3. Shanshan Wang
    4. Chao Qin
    5. Youliang Rao
    6. Pinghui Feng
    7. Xiaojiang S. Chen

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. ACE2-independent SARS-CoV-2 infection and mouse adaption emerge after passage in cells expressing human and mouse ACE2

    1. Kexin Yan
    2. Troy Dumenil
    3. Bing Tang
    4. Thuy T. Le
    5. Cameron Bishop
    6. Andreas Suhrbier
    7. Daniel J. Rawle

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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