Microbiology

  1. SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation

    1. Jung-Hyun Choi
    2. Xu Zhang
    3. Christine Zhang
    4. David L. Dai
    5. Jun Luo
    6. Reese Ladak
    7. Qian Li
    8. Shane Wiebe
    9. Alex C.H. Liu
    10. Xiaozhuo Ran
    11. Jiaqi Yang
    12. Parisa Naeli
    13. Aitor Garzia
    14. Lele Zhou
    15. Niaz Mahmood
    16. Qiyun Deng
    17. Mohamed Elaish
    18. Rongtuan Lin
    19. Tom Hobman
    20. Jerry Pelletier
    21. Tommy Alain
    22. Silvia Vidal
    23. Thomas Duchaine
    24. Mohammad T. Mazhab-Jafari
    25. Xiaojuan Mao
    26. Seyed Mehdi Jafarnejad
    27. Nahum Sonenberg

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  2. SARS-CoV-2 Omicron efficiently infects human airway, but not alveolar epithelium

    1. Mart M. Lamers
    2. Anna Z. Mykytyn
    3. Tim I. Breugem
    4. Nathalie Groen
    5. Kèvin Knoops
    6. Debby Schipper
    7. Romy van Acker
    8. Petra B. van den Doel
    9. Theo Bestebroer
    10. Charlotte D. Koopman
    11. Chantal Reusken
    12. Mauro J. Muraro
    13. Corine H. GeurtsvanKessel
    14. Martin E. van Royen
    15. Peter J. Peters
    16. Jingshu Zhang
    17. Bart L. Haagmans

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Prediction and validation of host cleavage targets of SARS-CoV-2 3C-like protease

    1. Nora Yucel
    2. Silvia Marchiano
    3. Evan Tchelepi
    4. Germana Paterlini
    5. Quentin McAfee
    6. Nehaar Nimmagadda
    7. Andy Ren
    8. Sam Shi
    9. Charles Murry
    10. Zoltan Arany

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Inhibiting host-protein deposition on urinary catheters reduces associated urinary tract infections

    1. Marissa Jeme Andersen
    2. ChunKi Fong
    3. Alyssa Ann La Bella
    4. Jonathan Jesus Molina
    5. Alex Molesan
    6. Matthew M Champion
    7. Caitlin Howell
    8. Ana L Flores-Mireles

    • Curated by eLife

      Evaluation Summary:

      In a set of in vitro and in vivo experiments the investigators demonstrated that coating of urinary tract catheters with fibrinogen-degrading substances reduced adhesion and colonization with a broad range of bacteria relevant in the pathogenesis of CAUTI. This approach might, therefore, be interesting for prevention of CAUTI as an alternative to catheters coated with antibiotics.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  5. Nirmatrelvir, Molnupiravir, and Remdesivir maintain potent in vitro activity against the SARS-CoV-2 Omicron variant

    1. Romel Rosales
    2. Briana L. McGovern
    3. M. Luis Rodriguez
    4. Devendra K. Rai
    5. Rhonda D. Cardin
    6. Annaliesa S. Anderson
    7. PSP study group
    8. Emilia Mia Sordillo
    9. Harm van Bakel
    10. Viviana Simon
    11. Adolfo García-Sastre
    12. Kris M. White

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Differences in environmental stability among SARS-CoV-2 variants of concern: Omicron has higher stability

    1. Ryohei Hirose
    2. Yoshito Itoh
    3. Hiroshi Ikegaya
    4. Hajime Miyazaki
    5. Naoto Watanabe
    6. Takuma Yoshida
    7. Risa Bandou
    8. Tomo Daidoji
    9. Takaaki Nakaya

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Nirmatrelvir, an orally active Mpro inhibitor, is a potent inhibitor of SARS-CoV-2 Variants of Concern

    1. Devendra K. Rai
    2. Irina Yurgelonis
    3. Patricia McMonagle
    4. Hussin A. Rothan
    5. Li Hao
    6. Alexey Gribenko
    7. Elizabeth Titova
    8. Barry Kreiswirth
    9. Kris M. White
    10. Yuao Zhu
    11. Annaliesa S. Anderson
    12. Rhonda D. Cardin

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  8. SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

    1. Justin J. Frere
    2. Randal A. Serafini
    3. Kerri D. Pryce
    4. Marianna Zazhytska
    5. Kohei Oishi
    6. Ilona Golynker
    7. Maryline Panis
    8. Jeffrey Zimering
    9. Shu Horiuchi
    10. Daisy A. Hoagland
    11. Rasmus Møller
    12. Anne Ruiz
    13. Albana Kodra
    14. Jonathan B. Overdevest
    15. Peter D. Canoll
    16. Alain C. Borczuk
    17. Vasuretha Chandar
    18. Yaron Bram
    19. Robert Schwartz
    20. Stavros Lomvardas
    21. Venetia Zachariou
    22. Benjamin R. tenOever

    Reviewed by Rapid Reviews Infectious Diseases, ScreenIT

    3 evaluationsAppears in 2 listsLatest version Latest activity

  9. ASGR1 is a candidate receptor for SARS-CoV-2 that promotes infection of liver cells

    1. Xinyi Yang
    2. Yuqi Zhu
    3. Xiaying Zhao
    4. Jun Liu
    5. Jiangna Xun
    6. Songhua Yuan
    7. Jun Chen
    8. Hanyu Pan
    9. Jinlong Yang
    10. Jing Wang
    11. Zhimin Liang
    12. Xiaoting Shen
    13. Yue Liang
    14. Qinru Lin
    15. Huitong Liang
    16. Min Li
    17. Hongzhou Lu
    18. Huanzhang Zhu

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Modelling how the altered usage of cell entry pathways by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors

    1. Pranesh Padmanabhan
    2. Narendra M. Dixit

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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