1. An mRNA vaccine candidate for the SARS-CoV-2 Omicron variant

    This article has 8 authors:
    1. Jinkai Zang
    2. Chao Zhang
    3. Yannan Yin
    4. Shiqi Xu
    5. Weihua Qiao
    6. Dimitri Lavillette
    7. Haikun Wang
    8. Zhong Huang

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    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19

    This article has 12 authors:
    1. Carolin M. Lieber
    2. Robert M Cox
    3. Julien Sourimant
    4. Josef D. Wolf
    5. Kate Juergens
    6. Quynh Phung
    7. Manohar T Saindane
    8. Michael G Natchus
    9. George R Painter
    10. Kaori Sakamoto
    11. Alexander L. Greninger
    12. Richard K Plemper

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  3. Primary macrophages exhibit a modest inflammatory response early in SARS-CoV-2 infection

    This article has 4 authors:
    1. Ziyun Zhang
    2. Rebecca Penn
    3. Wendy S Barclay
    4. Efstathios S Giotis

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  4. VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry

    This article has 22 authors:
    1. Shilei Ding
    2. Irfan Ullah
    3. Shang Yu Gong
    4. Jonathan R. Grover
    5. Mohammadjavad Mohammadi
    6. Yaozong Chen
    7. Dani Vézina
    8. Guillaume Beaudoin-Bussières
    9. Vijay Tailor Verma
    10. Guillaume Goyette
    11. Fleur Gaudette
    12. Jonathan Richard
    13. Derek Yang
    14. Amos B. Smith
    15. Marzena Pazgier
    16. Marceline Côté
    17. Cameron Abrams
    18. Priti Kumar
    19. Walther Mothes
    20. Pradeep D. Uchil
    21. Andrés Finzi
    22. Christian Baron

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  5. Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

    This article has 22 authors:
    1. David W. Hawman
    2. Kimberly Meade-White
    3. Chad Clancy
    4. Jacob Archer
    5. Troy Hinkley
    6. Shanna S. Leventhal
    7. Deepashri Rao
    8. Allie Stamper
    9. Matthew Lewis
    10. Rebecca Rosenke
    11. Kyle Krieger
    12. Samantha Randall
    13. Amit P. Khandhar
    14. Linhue Hao
    15. Tien-Ying Hsiang
    16. Alexander L. Greninger
    17. Michael Gale
    18. Peter Berglund
    19. Deborah Heydenburg Fuller
    20. Kyle Rosenke
    21. Heinz Feldmann
    22. Jesse H. Erasmus

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  6. Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples

    This article has 9 authors:
    1. Olivia C. Lenz
    2. Andrew D. Marques
    3. Brendan J. Kelly
    4. Kyle G. Rodino
    5. Stephen D. Cole
    6. Ranawaka A.P.M. Perera
    7. Susan R. Weiss
    8. Frederic D. Bushman
    9. Elizabeth M. Lennon

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  7. Why SARS-CoV-2 Omicron variant is milder? A single high-frequency mutation of structural envelope protein matters

    This article has 8 authors:
    1. Bingqing Xia
    2. Yi wang
    3. Xiaoyan pan
    4. Xi Cheng
    5. Hongying Ji
    6. Xiaoli Zuo
    7. Jia Li
    8. Zhaobing Gao

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  8. Intracellular Flow Cytometry Complements RT-qPCR Detection of Circulating SARS-CoV-2 Variants of Concern

    This article has 6 authors:
    1. Emiel Vanhulle
    2. Becky Provinciael
    3. Joren Stroobants
    4. Anita Camps
    5. Piet Maes
    6. Kurt Vermeire

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  9. Interactions between strains govern the eco-evolutionary dynamics of microbial communities

    This article has 5 authors:
    1. Akshit Goyal
    2. Leonora S Bittleston
    3. Gabriel E Leventhal
    4. Lu Lu
    5. Otto X Cordero
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      The authors attempt to derive a threshold of genetic distance, beyond which two microbial strains diverge in their behavior in an ecological community. The question is of broad interest to ecology, especially microbial ecology. To answer this question, the authors followed the population dynamics of individual strains derived from a natural microbial community under constant environmental conditions in the lab. The statistical framework could be improved, and a more rigorous account of how the phylogenetic inference of strains and species was made should be given.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

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  10. A pseudotyped lentivirus-based assay to titer SARS-CoV-2 neutralizing antibodies in Mexico

    This article has 9 authors:
    1. José Antonio Cruz-Cardenas
    2. Michelle Gutierrez-Mayret
    3. Alejandra López-Arredondo
    4. Julio Enrique Castañeda-Delgado
    5. Augusto Rojas-Martinez
    6. Gerardo García-Rivas
    7. José Antonio Enciso-Moreno
    8. Laura A. Palomares
    9. Marion E. G. Brunck

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