Microbiology

  1. SARS-CoV-2 variant of concern type and biological sex affect efficacy of molnupiravir in dwarf hamster model of severe COVID-19

    1. Carolin M. Lieber
    2. Robert M Cox
    3. Julien Sourimant
    4. Josef D. Wolf
    5. Kate Juergens
    6. Quynh Phung
    7. Manohar T Saindane
    8. Michael G Natchus
    9. George R Painter
    10. Kaori Sakamoto
    11. Alexander L. Greninger
    12. Richard K Plemper

    Reviewed by ScreenIT

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  2. Primary macrophages exhibit a modest inflammatory response early in SARS-CoV-2 infection

    1. Ziyun Zhang
    2. Rebecca Penn
    3. Wendy S Barclay
    4. Efstathios S Giotis

    Reviewed by ScreenIT

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  3. VE607 stabilizes SARS-CoV-2 Spike in the “RBD-up” conformation and inhibits viral entry

    1. Shilei Ding
    2. Irfan Ullah
    3. Shang Yu Gong
    4. Jonathan R. Grover
    5. Mohammadjavad Mohammadi
    6. Yaozong Chen
    7. Dani Vézina
    8. Guillaume Beaudoin-Bussières
    9. Vijay Tailor Verma
    10. Guillaume Goyette
    11. Fleur Gaudette
    12. Jonathan Richard
    13. Derek Yang
    14. Amos B. Smith
    15. Marzena Pazgier
    16. Marceline Côté
    17. Cameron Abrams
    18. Priti Kumar
    19. Walther Mothes
    20. Pradeep D. Uchil
    21. Andrés Finzi
    22. Christian Baron

    Reviewed by ScreenIT

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  4. Replicating RNA platform enables rapid response to the SARS-CoV-2 Omicron variant and elicits enhanced protection in naïve hamsters compared to ancestral vaccine

    1. David W. Hawman
    2. Kimberly Meade-White
    3. Chad Clancy
    4. Jacob Archer
    5. Troy Hinkley
    6. Shanna S. Leventhal
    7. Deepashri Rao
    8. Allie Stamper
    9. Matthew Lewis
    10. Rebecca Rosenke
    11. Kyle Krieger
    12. Samantha Randall
    13. Amit P. Khandhar
    14. Linhue Hao
    15. Tien-Ying Hsiang
    16. Alexander L. Greninger
    17. Michael Gale
    18. Peter Berglund
    19. Deborah Heydenburg Fuller
    20. Kyle Rosenke
    21. Heinz Feldmann
    22. Jesse H. Erasmus

    Reviewed by ScreenIT

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  5. Detection and Interspecies Comparison of SARS-CoV-2 Delta Variant (AY.3) in Feces from a Domestic Cat and Human Samples

    1. Olivia C. Lenz
    2. Andrew D. Marques
    3. Brendan J. Kelly
    4. Kyle G. Rodino
    5. Stephen D. Cole
    6. Ranawaka A.P.M. Perera
    7. Susan R. Weiss
    8. Frederic D. Bushman
    9. Elizabeth M. Lennon

    Reviewed by ScreenIT

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  6. Why SARS-CoV-2 Omicron variant is milder? A single high-frequency mutation of structural envelope protein matters

    1. Bingqing Xia
    2. Yi wang
    3. Xiaoyan pan
    4. Xi Cheng
    5. Hongying Ji
    6. Xiaoli Zuo
    7. Jia Li
    8. Zhaobing Gao

    Reviewed by ScreenIT

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  7. Intracellular Flow Cytometry Complements RT-qPCR Detection of Circulating SARS-CoV-2 Variants of Concern

    1. Emiel Vanhulle
    2. Becky Provinciael
    3. Joren Stroobants
    4. Anita Camps
    5. Piet Maes
    6. Kurt Vermeire

    Reviewed by ScreenIT

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  8. Interactions between strains govern the eco-evolutionary dynamics of microbial communities

    1. Akshit Goyal
    2. Leonora S Bittleston
    3. Gabriel E Leventhal
    4. Lu Lu
    5. Otto X Cordero

    • Curated by eLife

      Evaluation Summary:

      The authors attempt to derive a threshold of genetic distance, beyond which two microbial strains diverge in their behavior in an ecological community. The question is of broad interest to ecology, especially microbial ecology. To answer this question, the authors followed the population dynamics of individual strains derived from a natural microbial community under constant environmental conditions in the lab. The statistical framework could be improved, and a more rigorous account of how the phylogenetic inference of strains and species was made should be given.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  9. A pseudotyped lentivirus-based assay to titer SARS-CoV-2 neutralizing antibodies in Mexico

    1. José Antonio Cruz-Cardenas
    2. Michelle Gutierrez-Mayret
    3. Alejandra López-Arredondo
    4. Julio Enrique Castañeda-Delgado
    5. Augusto Rojas-Martinez
    6. Gerardo García-Rivas
    7. José Antonio Enciso-Moreno
    8. Laura A. Palomares
    9. Marion E. G. Brunck

    Reviewed by ScreenIT

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  10. Engineering SARS-CoV-2 cocktail antibodies into a bispecific format improves neutralizing potency and breadth

    1. Zhiqiang Ku
    2. Xuping Xie
    3. Jianqing Lin
    4. Peng Gao
    5. Abbas El Sahili
    6. Hang Su
    7. Yang Liu
    8. Xiaohua Ye
    9. Xin Li
    10. Xuejun Fan
    11. Boon Chong Goh
    12. Wei Xiong
    13. Hannah Boyd
    14. Antonio E. Muruato
    15. Hui Deng
    16. Hongjie Xia
    17. Zou Jing
    18. Birte K. Kalveram
    19. Vineet D. Menachery
    20. Ningyan Zhang
    21. Julien Lescar
    22. Pei-Yong Shi
    23. Zhiqiang An

    Reviewed by ScreenIT

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