Microbiology

  1. Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

    1. Dhrumi Shah
    2. Nikita Rewatkar
    3. Adishree M
    4. Siddhi Gupta
    5. Sudharsan Mathivathanan
    6. Sayantani Biswas
    7. Sriram Varahan

    • Curated by eLife

      eLife assessment

      The authors identify a novel, conserved link between glycolytic flux and sulfur amino acid metabolism that governs fungal morphological differentiation independently of the cAMP-PKA pathway. This represents an important conceptual advance in understanding metabolic control of development and virulence. While the evidence supporting this connection is compelling, the mechanistic basis of how glycolysis regulates the Met30/Met4 axis requires further experimental clarification.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  2. Vitamin B 2 Production by Vaginal Lactobacilli Promotes Symbiosis

    1. Caroline E.M.K. Dricot
    2. Denise M. Selegato
    3. Tim Van Rillaer
    4. Eline Cauwenberghs
    5. Isabel Erreygers
    6. Margo Hiel
    7. Amber Brauer-Nikonow
    8. Annelies Breynaert
    9. Stefanie Wijnants
    10. Isabel Pintelon
    11. Sandra Condori
    12. Sarah Ahannach
    13. Thies Gehrmann
    14. Sam Bakelants
    15. Nina Hermans
    16. Patrick Van Dijck
    17. Michael France
    18. Irina Spacova
    19. Jacques Ravel
    20. Michael Zimmermann
    21. Sarah Lebeer

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  3. Microfluidic Droplet-Assisted Single-Cell Raman Sorting for High-Throughput Screening of Functional Lignin-Degrading Microbes

    1. Tingting Jia
    2. Manling Zhang
    3. Huicheng Chen
    4. Ling Lu
    5. Lin Wang
    6. Yunhua Wang
    7. Guoxia Zheng

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  4. Early Pregnancy Marks Significant Shifts in the Oral Microbiome

    1. Shani Finkelstein
    2. Sigal Frishman
    3. Sondra Turjeman
    4. Oshrit Shtossel
    5. Evgeny Tikhonov
    6. Meital Nuriel-Ohayon
    7. Yishay Pinto
    8. Polina Popova
    9. Alexandra S. Tkachuk
    10. Elena A. Vasukova
    11. Anna D. Anopova
    12. Evgenii A. Pustozerov
    13. Tatiana M. Pervunina
    14. Elena N. Grineva
    15. Moshe Hod
    16. Betty Schwartz
    17. Eran Hadar
    18. Omry Koren
    19. Yoram Louzoun

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  5. Stress granules formed during different RNA virus infections show remarkable plasticity and substantial virus-specific differences in their formation and composition

    1. Reto M. Lang
    2. Silvio Steiner
    3. Jenna Kelly
    4. Anne-Christine Uldry
    5. Pratik Dave
    6. Sophie Braga-Lagache
    7. Jeffrey Chao
    8. Manfred Heller
    9. Volker Thiel

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Tretinoin, a Vitamin A derivative, exerts antiviral effects against Chikungunya virus infection through the nuclear retinoid receptor signaling pathways

    1. Soumyajit Ghosh
    2. Chandan Mahish
    3. Archana Mahapatra
    4. Tathagata Mukherjee
    5. Pratima Kumari
    6. Bijita Bhowmick
    7. Saikat De
    8. Udvas Ghorai
    9. Rajshree Rajmohan Jena
    10. Seema Pradhan
    11. Subhasis Chattopadhyay
    12. Soma Chattopadhyay

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Ultra-deep long-read metagenomics captures diverse taxonomic and biosynthetic potential of soil microbes

    1. Caner Bağcı
    2. Timo Negri
    3. Elena Buena Atienza
    4. Caspar Gross
    5. Stephan Ossowski
    6. Nadine Ziemert

    Reviewed by GigaScience

    2 evaluationsAppears in 1 listLatest version Latest activity

  8. Research advance: Unexpected plasticity in the life cycle of Trypanosoma brucei

    1. Carina Praisler
    2. Jaime N Lisack
    3. Anna Sophie Kreis
    4. Laura Hauf
    5. Johanna Krenzer
    6. Fabian Imdahl
    7. Markus Engstler

    • Curated by eLife

      eLife Assessment

      The manuscript concerns a fundamental and controversial question in Trypanosoma brucei biology and the parasite life cycle, providing further evidence that slender bloodstream forms can indeed infect Tsetse flies. The study is solid in design and execution, and addresses several criticisms made of the authors' earlier work. Nevertheless, some of the main conclusions are only partially supported: one issue is how, precisely, a "slender" bloodstream form is defined, and discrepancies with some results from other laboratories remain unexplained.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  9. From ecology to evolution: plasmid- and colicin-mediated persistence of antibiotic resistant Escherichia coli in gulls

    1. Michaela Ruzickova
    2. Jana Palkovicova
    3. Kristina Nesporova
    4. Marketa Rysava
    5. Rene Pariza
    6. Simon Krejci
    7. Ivan Literak
    8. Monika Dolejska

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Discovery of a potent anti-Zika virus benzamide series targeting the viral protein NS4B

    1. Donghoon Chung
    2. Yuka Otsuka
    3. Eunjung Kim
    4. Sultan Ullah
    5. Nicole M. Kennedy
    6. Khac Huy Ngo
    7. Jinjoo Kang
    8. Reece Tomlison
    9. Brian Alejandro
    10. Koji Barnaby
    11. Jeffery Miller
    12. Justin Shumate
    13. Chwee Fang Teo
    14. Yaw Bia Tan
    15. Che Shin Chew
    16. CongBao Kang
    17. Dahai Luo
    18. Louis Scampavia
    19. Timothy P. Spicer
    20. Thomas D. Bannister

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity
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