Immunology

  1. Increased Potency and Breadth of SARS-CoV-2 Neutralizing Antibodies After a Third mRNA Vaccine Dose

    1. Frauke Muecksch
    2. Zijun Wang
    3. Alice Cho
    4. Christian Gaebler
    5. Tarek Ben Tanfous
    6. Justin DaSilva
    7. Eva Bednarski
    8. Victor Ramos
    9. Shuai Zong
    10. Brianna Johnson
    11. Raphael Raspe
    12. Dennis Schaefer-Babajew
    13. Irina Shimeliovich
    14. Mridushi Daga
    15. Kai-Hui Yao
    16. Fabian Schmidt
    17. Katrina G. Millard
    18. Martina Turroja
    19. Mila Jankovic
    20. Thiago Y. Oliveria
    21. Anna Gazumyan
    22. Marina Caskey
    23. Theodora Hatziioannou
    24. Paul D. Bieniasz
    25. Michel C. Nussenzweig

    Reviewed by ScreenIT

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  2. The BNT162b2 mRNA SARS-CoV-2 vaccine induces transient afucosylated IgG1 in naive but not in antigen-experienced vaccinees

    1. Julie Van Coillie
    2. Tamas Pongracz
    3. Johann Rahmöller
    4. Hung-Jen Chen
    5. Chiara Elisabeth Geyer
    6. Lonneke A. van Vught
    7. Jana Sophia Buhre
    8. Tonći Šuštić
    9. Thijs Luc Junior van Osch
    10. Maurice Steenhuis
    11. Willianne Hoepel
    12. Wenjun Wang
    13. Anne Sophie Lixenfeld
    14. Jan Nouta
    15. Sofie Keijzer
    16. Federica Linty
    17. Remco Visser
    18. Mads Delbo Larsen
    19. Emily Lara Martin
    20. Inga Künsting
    21. Selina Lehrian
    22. Vera von Kopylow
    23. Carsten Kern
    24. Hanna Bele Lunding
    25. Menno de Winther
    26. Niels van Mourik
    27. Theo Rispens
    28. Tobias Graf
    29. Marleen Adriana Slim
    30. René Peter Minnaar
    31. Marije Kristianne Bomers
    32. Jonne Jochum Sikkens
    33. Alexander P.J. Vlaar
    34. C. Ellen van der Schoot
    35. Jeroen den Dunnen
    36. Manfred Wuhrer
    37. Marc Ehlers
    38. Gestur Vidarsson
    39. Spinello Antinori
    40. Cinzia Bassoli
    41. Giovanna Bestetti
    42. Mario Corbellino
    43. Alice Covizzi
    44. Angelica Lupo
    45. Laura Milazzo
    46. Marco Schiuma
    47. Alessandro Torre
    48. Brent Appelman
    49. Diederik van de Beek
    50. Marije K. Bomers
    51. Justin de Brabander
    52. Matthijs C. Brouwer
    53. David T.P. Buis
    54. Nora Chekrouni
    55. Marit J. van Gils
    56. Menno D. de Jong
    57. Ayesha H.A. Lavell
    58. Niels van Mourik
    59. Sabine E. Olie
    60. Edgar J.G. Peters
    61. Tom D.Y. Reijnders
    62. Michiel Schinkel
    63. Alex R. Schuurman
    64. Jonne J. Sikkens
    65. Marleen A. Slim
    66. Yvo M. Smulders
    67. Alexander P.J. Vlaar
    68. Lonneke A. van Vught
    69. Joost W. Wiersinga

    Reviewed by ScreenIT

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  3. Omicron-specific and bivalent omicron-containing vaccine candidates elicit potent virus neutralisation in the animal model

    1. Asghar Abdoli
    2. Hamidreza Jamshidi
    3. Mohammad Taqavian
    4. Mehdi Lari Baghal
    5. Hasan Jalili

    Reviewed by ScreenIT

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  4. Redox regulation of PTPN22 affects the severity of T-cell-dependent autoimmune inflammation

    1. Jaime James
    2. Yifei Chen
    3. Clara M Hernandez
    4. Florian Forster
    5. Markus Dagnell
    6. Qing Cheng
    7. Amir A Saei
    8. Hassan Gharibi
    9. Gonzalo Fernandez Lahore
    10. Annika Åstrand
    11. Rajneesh Malhotra
    12. Bernard Malissen
    13. Roman A Zubarev
    14. Elias SJ Arnér
    15. Rikard Holmdahl

    • Curated by eLife

      Evaluation summary:

      This paper documents a novel aspect of how T cell activation is regulated by the PTPN22 phosphatase, namely reversible oxidation which transiently reduces the activity of PTPN22 to allow the T cell antigen receptor to drive a strong activation signal. This compelling work adds to our understanding of how an immune response is initiated and provides new insights that could be exploited for the development of new drugs to treat immune-mediated diseases.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  5. Milk of Cow and Goat, Immunized by Recombinant Protein Vaccine ZF-UZ-VAC2001(Zifivax), Contains Neutralizing Antibodies Against SARS-CoV-2 and Remains Active After Standard Milk Pasteurization

    1. Victoria Garib
    2. Stefani Katsamaki
    3. Shahlo Turdikulova
    4. Yuliya Levitskaya
    5. Nodira Zahidova
    6. Galina Bus
    7. Kristina Karamova
    8. Manona Rakhmedova
    9. Nigora Magbulova
    10. Alexander Bruhov
    11. Firuz Y. Garib
    12. Ibrokhim Y. Abdurakhmonov

    Reviewed by ScreenIT

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  6. Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

    1. Zhenhao Fang
    2. Lei Peng
    3. Renata Filler
    4. Kazushi Suzuki
    5. Andrew McNamara
    6. Qianqian Lin
    7. Paul A. Renauer
    8. Luojia Yang
    9. Bridget Menasche
    10. Angie Sanchez
    11. Ping Ren
    12. Qiancheng Xiong
    13. Madison Strine
    14. Paul Clark
    15. Chenxiang Lin
    16. Albert I. Ko
    17. Nathan D. Grubaugh
    18. Craig B. Wilen
    19. Sidi Chen

    Reviewed by ScreenIT

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  7. SARS-CoV-2-specific T cells associate with inflammation and reduced lung function in pulmonary post-acute sequalae of SARS-CoV-2

    1. Katherine M. Littlefield
    2. Renée O. Watson
    3. Jennifer M. Schneider
    4. Charles P. Neff
    5. Eiko Yamada
    6. Min Zhang
    7. Thomas B. Campbell
    8. Michael T. Falta
    9. Sarah E. Jolley
    10. Andrew P. Fontenot
    11. Brent E. Palmer

    Reviewed by ScreenIT

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  8. Dam–Infant Rhesus Macaque Pairs to Dissect Age-Dependent Responses to SARS-CoV-2 Infection

    1. Stephanie N Langel
    2. Carolina Garrido
    3. Caroline Phan
    4. Tatianna Travieso
    5. Helene Kirshner
    6. Todd DeMarco
    7. Zhong-Min Ma
    8. J Rachel Reader
    9. Katherine J Olstad
    10. Rebecca L Sammak
    11. Yashavanth Shaan Lakshmanappa
    12. Jamin W Roh
    13. Jennifer Watanabe
    14. Jodie Usachenko
    15. Ramya Immareddy
    16. Rachel Pollard
    17. Smita S Iyer
    18. Sallie Permar
    19. Lisa A Miller
    20. Koen K A Van Rompay
    21. Maria Blasi

    Reviewed by ScreenIT

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  9. Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model

    1. Jian Hang Lam
    2. Devendra Shivhare
    3. Teck Wan Chia
    4. Suet Li Chew
    5. Gaurav Sinsinbar
    6. Ting Yan Aw
    7. Siamy Wong
    8. Shrinivas Venkatraman
    9. Francesca Wei Inng Lim
    10. Pierre Vandepapeliere
    11. Madhavan Nallani

    Reviewed by ScreenIT

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  10. Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

    1. Liangxia Ai
    2. Yafei Li
    3. Li Zhou
    4. Wenrong Yao
    5. Hao Zhang
    6. Zhaoyu Hu
    7. Jinyu Han
    8. Weijie Wang
    9. Junmiao Wu
    10. Pan Xu
    11. Ruiyue Wang
    12. Zhangyi Li
    13. Zhouwang Li
    14. Chengliang Wei
    15. Jianqun Liang
    16. Haobo Chen
    17. Zhimiao Yang
    18. Ming Guo
    19. Zhixiang Huang
    20. Xin Wang
    21. Zhen Zhang
    22. Wenjie Xiang
    23. Dazheng Sun
    24. Lianqiang Xu
    25. Meiyan Huang
    26. Bin Lv
    27. Peiqi Peng
    28. Shangfeng Zhang
    29. Xuhao Ji
    30. Huiyi Luo
    31. Nanping Chen
    32. Jianping Chen
    33. Ke Lan
    34. Yong Hu

    Reviewed by ScreenIT

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