Immunology

  1. Single-cell analysis of signalling and transcriptional responses to type I interferons

    1. Rachel E Rigby
    2. Kevin Rue-Albrecht
    3. Aleksandr Fedorov
    4. David Sims
    5. Jan Rehwinkel

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  3. Single-molecule imaging of transcription dynamics, RNA localization and fate in human T cells

    1. M Valeria Lattanzio
    2. Nikolina Šoštarić
    3. Nandhini Kanagasabesan
    4. Branka Popović
    5. Antonia Bradarić
    6. Leyma Wardak
    7. Aurélie Guislain
    8. Philipp Savakis
    9. Evelina Tutucci
    10. Monika C Wolkers

    Reviewed by Review Commons

    3 evaluationsAppears in 1 listLatest version Latest activity

  6. Pediatric cerebrospinal fluid immune profiling distinguishes pediatric-onset multiple sclerosis from other pediatric-onset acute neurological disorders

    1. Diego A. Espinoza
    2. Tobias Zrzavy
    3. Gautier Breville
    4. Simon Thebault
    5. Amaar Marefi
    6. Ina Mexhitaj
    7. Luana D. Yamashita
    8. Mengyuan Kan
    9. Micky Bacchus
    10. Jessica Legaspi
    11. Samantha Fernandez
    12. Anna Melamed
    13. Mallory Stubblebine
    14. Yeseul Kim
    15. Zachary Martinez
    16. Caroline Diorio
    17. Andreas Schulte-Mecklenbeck
    18. Heinz Wiendl
    19. Ayman Rezk
    20. Rui Li
    21. Sona Narula
    22. Amy T. Waldman
    23. Sarah E. Hopkins
    24. Brenda Banwell
    25. Amit Bar-Or

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Coenzyme A governs proinflammatory macrophage metabolism

    1. Greg. A Timblin
    2. Kevin. M Tharp
    3. Johanna ten Hoeve
    4. Daniel S Kantner
    5. Ilayda Baydemir
    6. Eric A Noel
    7. Chandra Khantwal
    8. Pankaj K Singh
    9. Joshua N Farahzad
    10. Jorge Domínguez-Andrés
    11. Russell E Vance
    12. Nathaniel W Snyder
    13. Valerie M Weaver

    • Curated by eLife

      eLife Assessment

      This important study looks into the effect of exogenous CoA on the response of TLR4-activated macrophages. Specifically, CoA enhances the LPS response by examining metabolomics, 13C tracing, and assessments of transcription and acetylation. Together, these provide a compelling series of findings that show exogenous CoA is taken up by macrophages, and this facilitates histone acetylation and transcription associated with activation and antimicrobial activity.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity
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