Genomics

  1. Enhancing CRISPR prime editing by reducing misfolded pegRNA interactions

    1. Weiting Zhang
    2. Karl Petri
    3. Junyan Ma
    4. Hyunho Lee
    5. Chia-Lun Tsai
    6. J Keith Joung
    7. Jing-Ruey Joanna Yeh

    • Curated by eLife

      eLife assessment

      This useful paper reports on two simple methods for improving the efficiency of prime editing, a prominent gene editing technique. In combination with published modifications, the strategies described in this study may lead to significant improvements in editing efficiencies. The data are solid, and the methods will be of broad interest to anyone using gene editing.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  2. The genome of the colonial hydroid Hydractinia reveals that their stem cells use a toolkit of evolutionarily shared genes with all animals

    1. Christine E. Schnitzler
    2. E. Sally Chang
    3. Justin Waletich
    4. Gonzalo Quiroga-Artigas
    5. Wai Yee Wong
    6. Anh-Dao Nguyen
    7. Sofia N. Barreira
    8. Liam B. Doonan
    9. Paul Gonzalez
    10. Sergey Koren
    11. James M. Gahan
    12. Steven M. Sanders
    13. Brian Bradshaw
    14. Timothy Q. DuBuc
    15. Febrimarsa
    16. Danielle de Jong
    17. Eric P. Nawrocki
    18. Alexandra Larson
    19. Samantha Klasfeld
    20. Sebastian G. Gornik
    21. R. Travis Moreland
    22. Tyra G. Wolfsberg
    23. Adam M. Phillippy
    24. James C. Mullikin
    25. Oleg Simakov
    26. Paulyn Cartwright
    27. Matthew Nicotra
    28. Uri Frank
    29. Andreas D. Baxevanis

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  3. Haplogenome assembly reveals structural variation in Eucalyptus interspecific hybrids

    1. Anneri Lötter
    2. Tuan A Duong
    3. Julia Candotti
    4. Eshchar Mizrachi
    5. Jill L Wegrzyn
    6. Alexander A Myburg

    Reviewed by GigaScience

    2 evaluationsAppears in 1 listLatest version Latest activity

  4. SGLT2 transcriptomic expression atlas supports a kidney-centric role for empagliflozin’s benefits in heart failure

    1. Omar Mourad
    2. Shabana Vohra
    3. Sara S Nunes

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  5. A new haplotype-resolved turkey genome to enable turkey genetics and genomics research

    1. Carolina P Barros
    2. Martijn F L Derks
    3. Jeff Mohr
    4. Benjamin J Wood
    5. Richard P M A Crooijmans
    6. Hendrik-Jan Megens
    7. Marco C A M Bink
    8. Martien A M Groenen

    Reviewed by GigaScience

    2 evaluationsAppears in 1 listLatest version Latest activity

  6. Widespread of horizontal gene transfer events in eukaryotes

    1. Kun Li
    2. Fazhe Yan
    3. Zhongqu Duan
    4. David L. Adelson
    5. Chaochun Wei

    Reviewed by Arcadia Science

    26 evaluationsAppears in 1 listLatest version Latest activity

  7. Sensitive clustering of protein sequences at tree-of-life scale using DIAMOND DeepClust

    1. Benjamin Buchfink
    2. Haim Ashkenazy
    3. Klaus Reuter
    4. John A. Kennedy
    5. Hajk-Georg Drost

    Reviewed by Arcadia Science

    48 evaluationsAppears in 1 listLatest version Latest activity

  8. Genomic Variations in SARS-CoV-2 Genomes From Gujarat: Underlying Role of Variants in Disease Epidemiology

    1. Madhvi Joshi
    2. Apurvasinh Puvar
    3. Dinesh Kumar
    4. Afzal Ansari
    5. Maharshi Pandya
    6. Janvi Raval
    7. Zarna Patel
    8. Pinal Trivedi
    9. Monika Gandhi
    10. Labdhi Pandya
    11. Komal Patel
    12. Nitin Savaliya
    13. Snehal Bagatharia
    14. Sachin Kumar
    15. Chaitanya Joshi

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  9. Comprehensive variant and haplotype landscapes of 50,500 global SARS-CoV-2 isolates and accelerating accumulation of country-private variant profiles

    1. Lishuang Shen
    2. Jennifer Dien Bard
    3. Jaclyn A. Biegel
    4. Alexander R. Judkins
    5. Xiaowu Gai

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity

  10. A CRISPR-based SARS-CoV-2 diagnostic assay that is robust against viral evolution and RNA editing

    1. Kean Hean Ooi
    2. Jie Wen Douglas Tay
    3. Seok Yee Teo
    4. Mengying Mandy Liu
    5. Pornchai Kaewsapsak
    6. Shengyang Jin
    7. Yong-Gui Gao
    8. Meng How Tan

    Reviewed by ScreenIT

    1 evaluationAppears in 1 listLatest version Latest activity
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