Epidemiology

Assessing Healthy Vaccinee Effect in COVID-19 Vaccine Effectiveness Studies: A National Cohort Study in Qatar

1. Hiam Chemaitelly
2. Houssein H. Ayoub
3. Peter Coyle
4. Patrick Tang
5. Mohammad R. Hasan
6. Hadi M. Yassine
7. Asmaa A. Al Thani
8. Zaina Al-Kanaani
9. Einas Al-Kuwari
10. Andrew Jeremijenko
11. Anvar Hassan Kaleeckal
12. Ali Nizar Latif
13. Riyazuddin Mohammad Shaik
14. Hanan F. Abdul-Rahim
15. Gheyath K. Nasrallah
16. Mohamed Ghaith Al-Kuwari
17. Hamad Eid Al-Romaihi
18. Mohamed H. Al-Thani
19. Abdullatif Al-Khal
20. Roberto Bertollini
21. Adeel A. Butt
22. Laith J. Abu-Raddad

Reviewed by Rapid Reviews Infectious Diseases

Genomic epidemiology uncovers the timing and origin of the emergence of mpox in humans

1. Edyth Parker
2. Ifeanyi F. Omah
3. Patrick Varilly
4. Andrew Magee
5. Akeemat Opeyemi Ayinla
6. Ayotunde E. Sijuwola
7. Muhammad I. Ahmed
8. Oludayo O. Ope-ewe
9. Olusola Akinola Ogunsanya
10. Alhaji Olono
11. Philomena Eromon
12. Christopher H Tomkins-Tinch
13. James Richard Otieno
14. Olusola Akanbi
15. Abiodun Egwuenu
16. Odianosen Ehiakhamen
17. Chimaobi Chukwu
18. Kabiru Suleiman
19. Afolabi Akinpelu
20. Adama Ahmad
21. Khadijah Isa Imam
22. Richard Ojedele
23. Victor Oripenaye
24. Kenneth Ikeata
25. Sophiyah Adelakun
26. Babatunde Olajumoke
27. Delia Doreen Djuicy
28. Loique Landry Messanga Essengue
29. Moïse Henri Moumbeket Yifomnjou
30. Mark Zeller
31. Karthik Gangavarapu
32. Áine O’Toole
33. Daniel J Park
34. Gerald Mboowa
35. Sofonias Kifle Tessema
36. Yenew Kebede Tebeje
37. Onikepe Folarin
38. Anise Happi
39. Philippe Lemey
40. Marc A Suchard
41. Kristian G. Andersen
42. Pardis Sabeti
43. Andrew Rambaut
44. Richard Njoum
45. Chikwe Ihekweazu
46. Idriss Jide
47. Ifedayo Adetifa
48. Christian T Happi

Reviewed by Rapid Reviews Infectious Diseases

Protection afforded by post-infection SARS-CoV-2 vaccine doses: a cohort study in Shanghai

1. Bo Zheng
2. Bronner Gonçalves
3. Pengfei Deng
4. Weibing Wang
5. Jie Tian
6. Xueyao Liang
7. Ye Yao
8. Caoyi Xue

• Curated by eLife

  eLife assessment

  This important work by Zheng and colleagues uses a large cohort database from Shanghai to identify that post-infection vaccination among previously vaccinated individuals provides significant low to moderate protection against re-infection. The evidence supporting the conclusion is convincing with some limitations, e.g., lack of symptom severity as an outcome, and no inclusion of time since infection as an independent variable). This study will be of interest to vaccinologists, public health officials and clinicians.

Reviewed by eLife

Determinants of Timely Malaria Treatment among Under-Five Children Attending Public Health Facilities in Kisumu East Sub-County, Kenya: A Health Facility-Based Cross-Sectional Study

1. Geofrey Ochieng
2. Mutale Sampa
3. Patricia Maritim
4. Adam Silumbwe
5. Joseph M Zulu
6. Joseph Kato
7. Choolwe Jacobs

Reviewed by Rapid Reviews Infectious Diseases

How demographic factors matter for antimicrobial resistance – quantification of the patterns and impact of variation in prevalence of resistance by age and sex

1. Naomi R Waterlow
2. Ben S Cooper
3. Julie V Robotham
4. Gwenan M Knight

Reviewed by Rapid Reviews Infectious Diseases

Systematic evaluation of multifactorial causal associations for Alzheimer’s disease and an interactive platform MRAD developed based on Mendelian randomization analysis

1. Tianyu Zhao
2. Hui Li
3. Meishuang Zhang
4. Yang Xu
5. Ming Zhang
6. Li Chen

• Curated by eLife

  eLife assessment

  This important study introduces the MRAD database, an advancement in Alzheimer's disease research that provides a powerful tool for evaluating risk and protective factors through Mendelian randomization analysis. The evidence supporting the database's utility is solid, with findings backed by robust data, though addressing methodological concerns and ensuring more rigorous validation of associations would further strengthen its impact. This resource represents a significant leap forward in the field, offering unprecedented opportunities for researchers and clinicians to uncover key insights into Alzheimer's etiology, potentially revolutionizing how Alzheimer's research is approached and accelerating the discovery of new prevention strategies and treatments.

Reviewed by eLife

Estimating the potential impact of surveillance test-and-treat posts to reduce malaria in border regions in sub-Saharan Africa: a modelling study

1. Hillary M. Topazian
2. Giovanni D. Charles
3. Nora Schmit
4. Matteo Pianella
5. John M. Marshall
6. Immo Kleinschmidt
7. Katharina Hauck
8. Azra C. Ghani

Reviewed by Rapid Reviews Infectious Diseases

Forecasting the spatial spread of an Ebola epidemic in real-time: comparing predictions of mathematical models and experts

1. James D Munday
2. Alicia Rosello
3. W John Edmunds
4. Sebastian Funk

• Curated by eLife

  eLife assessment

  This manuscript provides valuable evidence comparing the performance of mathematical models and opinions from experts engaged in outbreak response in forecasting the spatial spread of an Ebola epidemic. The evidence supporting the conclusions is convincing though the work might have benefited from the use of more than two models in the ensemble predictions. It will be of interest to disease modellers, infectious disease epidemiologists, policy-makers, and those who need to inform policy-makers during an outbreak.

Reviewed by eLife

Risk of Inflammatory Bowel Disease Following Hospitalisation with Infectious Mononucleosis: A Danish Nationwide Cohort Study (1977-2021)

1. Anthony Ebert
2. Shania Harper
3. Marie V. Vestergaard
4. Wayne Mitchell
5. Tine Jess
6. Rahma Elmahdi

Reviewed by Rapid Reviews Infectious Diseases

Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States

1. Amanda C Perofsky
2. John Huddleston
3. Chelsea L Hansen
4. John R Barnes
5. Thomas Rowe
6. Xiyan Xu
7. Rebecca Kondor
8. David E Wentworth
9. Nicola Lewis
10. Lynne Whittaker
11. Burcu Ermetal
12. Ruth Harvey
13. Monica Galiano
14. Rodney Stuart Daniels
15. John W McCauley
16. Seiichiro Fujisaki
17. Kazuya Nakamura
18. Noriko Kishida
19. Shinji Watanabe
20. Hideki Hasegawa
21. Sheena G Sullivan
22. Ian G Barr
23. Kanta Subbarao
24. Florian Krammer
25. Trevor Bedford
26. Cécile Viboud

• Curated by eLife

  eLife assessment

  This paper explores the relationships among evolutionary and epidemiological quantities in influenza, and presents fundamental findings that substantially advance our understanding of the drivers of influenza epidemics. The authors use a rich set of data sources to gather and analyze compelling evidence on the roles of genetic distance, other influenza dynamics and epidemiological indicators in predicting influenza epidemics. The central findings highlight the significant influence of genetic distance on A(H3N2) virus epidemiology and emphasize the role of A(H1N1) virus incidence in shaping A(H3N2) epidemics, suggesting subtype interference as a key factor. This paper also makes relevant data available to the research community.

Reviewed by eLife