Investigation of an ongoing outbreak of ceftriaxone-resistant Salmonella enterica serovar Typhi in Bangladesh
This article has been Reviewed by the following groups
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- Evaluated articles (Rapid Reviews Infectious Diseases)
Abstract
We report an outbreak of ceftriaxone-resistant Salmonella Typhi in Bangladesh, with 47 cases identified from April-September 2024. Isolates belong to genotype 4.3.1.2 and harbor the bla CTX- M-15 gene on the pCROB1 plasmid. This unique genotype-plasmid lineage represents a recent introduction, necessitating enhanced surveillance, antimicrobial stewardship, and consideration of vaccination strategies.
Article activity feed
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Pham Thanh Duy
Review 3: "Investigation of an Ongoing Outbreak of Ceftriaxone-Resistant Salmonella Enterica Serovar Typhi in Bangladesh"
Reviewers emphasized the significance of public health, urging enhanced surveillance, treatment guideline updates, and consideration of typhoid vaccines.
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John Gunn, Peter Muturi
Review 2: "Investigation of an Ongoing Outbreak of Ceftriaxone-Resistant Salmonella Enterica Serovar Typhi in Bangladesh"
Reviewers emphasized the significance of public health, urging enhanced surveillance, treatment guideline updates, and consideration of typhoid vaccines.
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Hidemasa Izumiya
Review 1: "Investigation of an Ongoing Outbreak of Ceftriaxone-Resistant Salmonella Enterica Serovar Typhi in Bangladesh"
Reviewers emphasized the significance of public health, urging enhanced surveillance, treatment guideline updates, and consideration of typhoid vaccines.
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Strength of evidence
Reviewer(s): H Izumiya (National Institute of Infectious Diseases, Tokyo) | 📗📗📗📗◻️
J Gunn & P Muturi (The Ohio State University) | 📗📗📗📗◻️
P T Duy (Oxford University Clinical Research Unit) | 📘📘📘📘📘 -