Developmental Biology

PUFFFIN: A novel, ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods

1. Tamina Lebek
2. Mattias Malaguti
3. Alistair Elfick
4. Sally Lowell

Reviewed by Review Commons, preLights

Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification

1. Tim Petzold
2. Sarah Brivio
3. Tanja Linnerz
4. Masakatsu Watanabe
5. Holger Gerhardt
6. Julien Y. Bertrand

Reviewed by Review Commons

Lymphatic vessel development in human embryos

1. Shoichiro Yamaguchi
2. Natsuki Minamide
3. Hiroshi Imai
4. Tomoaki Ikeda
5. Masatoshi Watanabe
6. Kyoko Imanaka-Yoshida
7. Kazuaki Maruyama

Reviewed by Review Commons

KLF7 is a general inducer of human pluripotency

1. Mattia Arboit
2. Irene Zorzan
3. Marco Pellegrini
4. Paolo Martini
5. Elena Carbognin
6. Graziano Martello

Reviewed by Review Commons

Reconstructing stochastic cell population trajectories reveals regulators and heterogeneity of endothelial flow-migration coupling driving vascular remodelling

1. Wolfgang Giese
2. André Rosa
3. Elisabeth Baumann
4. Olya Oppenheim
5. Emir B. Akmeric
6. Santiago Andrade
7. Irene Hollfinger
8. Eireen Bartels-Klein
9. Silvanus Alt
10. Holger Gerhardt

Reviewed by Review Commons

Lineage-based scaling of germline intercellular bridges during oogenesis

1. Umayr Shaikh
2. Kathleen Sherlock
3. Julia Wilson
4. William Gilliland
5. Lindsay Lewellyn

Reviewed by Review Commons

ROCK and the actomyosin network control biomineral growth and morphology during sea urchin skeletogenesis

1. Eman Hijaze
2. Tsvia Gildor
3. Ronald Seidel
4. Majed Layous
5. Mark Winter
6. Luca Bertinetti
7. Yael Politi
8. Smadar Ben-Tabou de-Leon

• Curated by eLife

  eLife assessment

  This valuable study addresses the role of Rho-associated coiled-coil kinase (ROCK) and the cytoskeleton in the initiation and growth of the calcified endoskeleton of sea urchin embryos. Perturbation by two independent approaches (a morpholino and a selective inhibitor) provides convincing evidence that ROCK participates both in actomyosin regulation and in the gene regulatory network that controls skeletogenesis. Exciting areas of future work will be to elucidate the mechanisms by which ROCK influences gene expression and to further dissect the role of the cytoskeleton in mineralization.

Reviewed by eLife

Col4a2-eGFP mouse model reveals the molecular and functional dynamics of basement membrane remodelling in hair follicle morphogenesis

1. Duligengaowa Wuergezhen
2. Eleonore Gindroz
3. Ritsuko Morita
4. Kei Hashimoto
5. Takaya Abe
6. Hiroshi Kiyonari
7. Hironobu Fujiwara

Reviewed by Review Commons

JNK signaling-mediated exocytosis coordinates epithelial cell-turnover in Drosophila ribosomal protein mutants

1. Nanami Akai
2. Tatsushi Igaki
3. Shizue Ohsawa

Reviewed by Review Commons

A tension-induced morphological transition shapes the avian extra-embryonic territory

1. Arthur Michaut
2. Alexander Chamolly
3. Aurélien Villedieu
4. Francis Corson
5. Jérôme Gros

Reviewed by preLights