Cell Biology

  1. Human receptive endometrial assembloid for deciphering the implantation window

    1. Yu Zhang
    2. Rusong Zhao
    3. Chaoyan Yang
    4. Jinzhu Song
    5. Peishu Liu
    6. Yan Li
    7. Boyang Liu
    8. Tao Li
    9. Changjian Yin
    10. Minghui Lu
    11. Zhenzhen Hou
    12. Chuanxin Zhang
    13. Zi-Jiang Chen
    14. Keliang Wu
    15. Han Zhao

    • Curated by eLife

      eLife Assessment

      This important study reports an endometrial organoid culture system mimicking the window of implantation. The evidence supporting the conclusion drawn is convincing. The data will be of interest to embryologists and investigators working on reproductive biology and medicine.

    Reviewed by eLife

    11 evaluationsAppears in 1 listLatest version Latest activity

  2. Paclitaxel compromises nuclear integrity in interphase through SUN2-mediated cytoskeletal coupling

    1. Thomas Hale
    2. Victoria L Hale
    3. Piotr Kolata
    4. Ália dos Santos
    5. Matteo Allegretti

    Reviewed by preLights, Review Commons

    9 evaluationsAppears in 2 listsLatest version Latest activity

  3. Dissociation of the nuclear basket triggers chromosome loss in aging yeast

    1. Mihailo Mirkovic
    2. Jordan McCarthy
    3. Anne Cornelis Meinema
    4. Julie Parenteau
    5. Sung Sik Lee
    6. Sherif Abou Elela
    7. Yves Barral

    • Curated by eLife

      eLife Assessment

      This fundamental study reveals that aging in yeast leads to chromosome mis-segregation due to asymmetric partitioning of chromosomes, driven by disruption of the nuclear pore complex and pre-mRNA leakage. The findings are convincingly supported by carefully-designed experimental data with a combination of genetic, molecular biology and cell biology approaches.

    Reviewed by eLife

    10 evaluationsAppears in 1 listLatest version Latest activity

  4. Nucleus softens during herpesvirus infection

    1. Aapo Tervonen
    2. Simon Leclerc
    3. Visa Ruokolainen
    4. Katie Tieu
    5. Sébastien Lyonnais
    6. Henri Niskanen
    7. Jian-Hua Chen
    8. Alka Gupta
    9. Minna U Kaikkonen
    10. Carolyn A Larabell
    11. Delphine Muriaux
    12. Salla Mattola
    13. Daniel E Conway
    14. Teemu O Ihalainen
    15. Vesa Aho
    16. Maija Vihinen-Ranta

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Targeting ZNRF3 and RNF43 to Restore Regeneration and Reverse Metabolic Dysfunction-Associated Steatotic Liver Disease

    1. Federico Di Tullio
    2. Sue Bin Yang
    3. Lida Yang
    4. Bruno Cogliati
    5. Shamsa Roshan
    6. Kaiyuan Guo
    7. Abigail Glezer
    8. Jonathan Conrad
    9. Siddarth Vinod Kumar
    10. Joana Almeida
    11. Haoyuan Li
    12. Shahina Saeed
    13. Marina Barcena-varela
    14. Emily Bramel
    15. Anthony Lozano
    16. Lianyong Su
    17. Derrick Zhao
    18. Huong Pham
    19. Fanglin Ma
    20. Amaia Lujambio
    21. Sai Ma
    22. Yizhou Dong
    23. Huiping Zhou
    24. Tianliang Sun

    Reviewed by PREreview

    1 evaluationAppears in 1 listLatest version Latest activity

  6. Orderly mitosis shapes interphase genome architecture

    1. Krishnendu Guin
    2. Adib Keikhosravi
    3. Raj Chari
    4. Gianluca Pegoraro
    5. Tom Misteli

    • Curated by eLife

      eLife Assessment

      This valuable study combines microscopy and CRISPR screening in two different cell lines to identify factors involved in global chromatin organization, using centromere clustering as a proxy. Follow-up cell cycle synchronisation studies confirm roles in centromere clustering in mitosis. However, incomplete characterisation of the cell lines used limits the interpretation of the findings. The study will interest researchers studying genome organisation in mitosis.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  7. Spatial control of secretory vesicle targeting by the Ync13–Rga7– Rng10 complex during cytokinesis

    1. Sha Zhang
    2. Davinder Singh
    3. Yi-Hua Zhu
    4. Katherine J. Zhang
    5. Alejandro Melero
    6. Sophie G. Martin
    7. Jian-Qiu Wu

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity

  8. Large-scale identification of plasma membrane repair proteins revealed spatiotemporal cellular responses to plasma membrane damage

    1. Yuta Yamazaki
    2. Keiko Kono

    • Curated by eLife

      eLife Assessment

      This work provides an important resource identifying 72 proteins as novel candidates for plasma membrane and/or cell wall damage repair in budding yeast, and describes the temporal coordination of exocytosis and endocytosis during the repair process. The data are convincing; however, additional experimental validation will better support the claim that repair proteins shuttle between the bud tip and the damage site.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  9. MCL1 may not mediate chemoresistance

    1. Kylin A. Emhoff
    2. Kunho Chung
    3. Dongmei Zhang
    4. Belinda Willard
    5. Timothy Chan
    6. Babal Kant Jha
    7. Shaun R. Stauffer
    8. Jesse A. Coker
    9. Jan Joseph Melenhorst

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Multiciliated cells adapt the mechanochemical Piezo1-Erk1/2-Yap1 cell proliferation axis to fine-tune centriole number

    1. Vani Narayanan
    2. Venkatramanan G Rao
    3. Angelo Arrigo
    4. Saurabh S Kulkarni

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity
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