Cell Biology

  2. Liver regeneration by a population of midzone-located mesenchymal-hepatocyte hybrid cells

    1. Guo Yu
    2. Shaoyang Zhang
    3. Ana Romo
    4. Soma Biswas
    5. Baojie Li
    6. Jing Li

    • Curated by eLife

      eLife assessment

      This study is partly useful as it corroborates what is already known about the elevated proliferation capacity of mid lobular hepatocytes in liver regeneration. Lineage tracing and scRNAseq studies are powerful for the investigation of such heterogeneous hepatocyte proliferation capacity. Nevertheless, based on experimental limitations, incomplete method description and inadequate data analyses the presented data are insufficient to support the proposed conclusions of a mesenchymal-hepatocyte hybrid population in the murine liver.

    Reviewed by eLife

    3 evaluationsAppears in 1 listLatest version Latest activity

  3. CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans

    1. Rachel Webster
    2. Maria Quintana
    3. Bin Yu
    4. Stacey Fluke
    5. Ran Kafri
    6. W. Brent Derry

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  4. Excess microtubule and F-actin formation mediates shortening and loss of primary cilia in response to a hyperosmotic milieu

    1. Hiroshi Otani
    2. Ryota Nakazato
    3. Kanae Koike
    4. Keisuke Ohta
    5. Koji Ikegami

    Reviewed by Arcadia Science

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Autoacetylation-mediated phase separation of TIP60 is critical for its functions

    1. Shraddha Dubey
    2. Himanshu Gupta
    3. Ashish Gupta

    • Curated by eLife

      eLife assessment

      This is a valuable study on K187 acetylation of the nuclear protein, TIP60, required for its phase separation and function. The evidence supporting the primary conclusion is incomplete and warrants more scrutiny.

    Reviewed by eLife

    5 evaluationsAppears in 1 listLatest version Latest activity

  6. CEP44 is required for maintaining centriole duplication and spindle integrity

    1. Donghui Zhang
    2. Wenlu Wei
    3. Xiaopeng Zou
    4. Hui Meng
    5. Fangyuan Li
    6. Minjun Yao
    7. Junling Teng
    8. Ning Huang
    9. Jianguo Chen

    • Curated by eLife

      eLife assessment

      This useful study investigates the role of the centrosomal protein CEP44 in centriole duplication and mitotic spindle formation. While the analysis of CEP44 mitotic phosphorylation and spindle recruitment is solid, the characterization of CEP44's role at centrioles is incomplete and would benefit from additional controls and analyses. Since the work links CEP44 reduced expression to poor survival in breast cancer patients, it is of interest not only to cell biologists but also to cancer researchers.

    Reviewed by eLife

    4 evaluationsAppears in 1 listLatest version Latest activity

  8. Mantis: High-throughput 4D imaging and analysis of the molecular and physical architecture of cells

    1. Ivan E Ivanov
    2. Eduardo Hirata-Miyasaki
    3. Talon Chandler
    4. Rasmi Cheloor-Kovilakam
    5. Ziwen Liu
    6. Soorya Pradeep
    7. Chad Liu
    8. Madhura Bhave
    9. Sudip Khadka
    10. Carolina Arias
    11. Manuel D Leonetti
    12. Bo Huang
    13. Shalin B Mehta

    Reviewed by Arcadia Science

    2 evaluationsAppears in 1 listLatest version Latest activity

  9. Yeast TLDc domain-containing proteins control assembly and subcellular localization of the V-ATPase

    1. Samira Klössel
    2. Ying Zhu
    3. Lucia Amado
    4. Daniel D. Bisinski
    5. Julia Ruta
    6. Fan Liu
    7. Ayelén González Montoro

    Reviewed by Review Commons

    4 evaluationsAppears in 1 listLatest version Latest activity
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