Cell Biology

MTMR regulates KRAS function by controlling plasma membrane levels of phospholipids

1. Taylor E. Lange
2. Ali Naji
3. Ransome van der Hoeven
4. Hong Liang
5. Yong Zhou
6. Gerald R.V. Hammond
7. John F. Hancock
8. Kwang-jin Cho

Reviewed by Review Commons

Dynamic localization of the chromosomal passenger complex in trypanosomes is controlled by the orphan kinesins KIN-A and KIN-B

1. Daniel Ballmer
2. Bungo Akiyoshi

• Curated by eLife

  eLife assessment

  This important study identifies the mitotic localization mechanism for Aurora B and INCENP (parts of the chromosomal passenger complex, CPC) in Trypanosoma brucei. The mechanism differs from that in the more commonly studied opisthokonts and is supported by compelling RNAi and imaging experiments, targeted mutations, immunoprecipitations with crosslinking/mass spec, and AlphaFold interaction predictions. The findings will be of interest to cell biologists working on cell division, parasitologists, and those interested in the evolution of mitotic mechanisms.

Reviewed by eLife

KIF1C, an RNA transporting kinesin-3, undergoes liquid-liquid phase separation through its C-terminal disordered domain

1. Qi Geng
2. Jakia Jannat Keya
3. Takashi Hotta
4. Kristen J Verhey

Reviewed by Review Commons

Reduction of cortical pulling at mitotic entry facilitates aster centration

1. Anne Rosfelter
2. Ghislain de Labbey
3. Janet Chenevert
4. Rémi Dumollard
5. Sebastien Schaub
6. Zoltan Machaty
7. Lydia Besnardeau
8. Daniel Gonzalez Suarez
9. Céline Hebras
10. Hervé Turlier
11. David R. Burgess
12. Alex McDougall

Reviewed by Review Commons

Identification of plants’ functional counterpart of the metazoan mediator of DNA Damage checkpoint 1

1. Zdravko J Lorković
2. Michael Klingenbrunner
3. Chung Hyun Cho
4. Frédéric Berger

Reviewed by Review Commons

Mammalian glial protrusion transcriptomes predict localization of Drosophila glial transcripts required for synaptic plasticity

1. Dalia S. Gala
2. Jeffrey Y. Lee
3. Maria Kiourlappou
4. Joshua S. Titlow
5. Rita O. Teodoro
6. Ilan Davis

Reviewed by Review Commons, Arcadia Science

LiverZap: a chemoptogenetic tool for global and locally restricted hepatocyte ablation to study cellular behaviours in liver regeneration

1. Elizabeth M. G. Ambrosio
2. Charlotte S. L. Bailey
3. Iris A. Unterweger
4. Jens B. Christensen
5. Marcel P. Bruchez
6. Pia R. Lundegaard
7. Elke A. Ober

Reviewed by Review Commons

Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes

1. Jana Riegger
2. Rolf E Brenner

Reviewed by Review Commons

Structural evidence for elastic tethers connecting separating chromosomes in crane-fly spermatocytes

1. Arthur Forer
2. Shotaro Otsuka

Reviewed by Review Commons

Characterisation of TbSmee1 indicates that endocytosis is required for access of surface-bound cargo to the trypanosome flagellar pocket

1. Daja Schichler
2. Antonia Konle
3. Eva-Maria Spath
4. Sina Riegler
5. Alexandra Klein
6. Anna Seleznev
7. Sisco Jung
8. Timothy Wuppermann
9. Noah Wetterich
10. Alyssa Borges
11. Elisabeth Meyer-Natus
12. Katharina Havlicek
13. Sonia Pérez Cabrera
14. Korbinian Niedermüller
15. Sara Sajko
16. Maximilian Dohn
17. Xenia Malzer
18. Emily Riemer
19. Tuguldur Tumurbaatar
20. Kristina Djinovic-Carugo
21. Gang Dong
22. Christian J. Janzen
23. Brooke Morriswood

Reviewed by Review Commons