Cancer Biology

Post-transcriptional control drives Aurora kinase A expression in human cancers

1. Roberta Cacioppo
2. Deniz Rad
3. Giulia Pagani
4. Paolo Gandellini
5. Catherine Lindon

Reviewed by Review Commons

Comparison of Tug-of-War Models Assuming Moran versus Branching Process Population Dynamics

1. Khanh N. Dinh
2. Monika K. Kurpas
3. Marek Kimmel

• Curated by eLife

  eLife assessment

  This study uses numerical simulations to characterize and compare variants of two widely used mathematical models and then applies those models to inferring evolutionary parameters from breast cancer data. The copious numerical results will be of some interest to mathematical biologists working with similar models. The finding that many breast cancer mutations are mildly deleterious is valuable but the evidence supporting this claim is incomplete because the mathematical modelling and statistical methods are insufficiently justified and inadequately validated.

Reviewed by eLife

STIL overexpression shortens lifespan and reduces tumor formation in mice

1. Amira-Talaat Moussa
2. Marco R. Cosenza
3. Timothy Wohlfromm
4. Katharina Brobeil
5. Anthony Hill
6. Annarita Patrizi
7. Karin Müller-Decker
8. Tim Holland-Letz
9. Anna Jauch
10. Bianca Kraft
11. Alwin Krämer

Reviewed by Review Commons

Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration

1. Montserrat Llanses Martinez
2. Keqian Nan
3. Zhe Bao
4. Rachele Bacchetti
5. Shengnan Yuan
6. Joe Tyler
7. Xavier Le Guezennec
8. Frédéric A. Bard
9. Elena Rainero

Reviewed by Review Commons