Bioinformatics

A Structural Proteome Screen Identifies Protein Mimicry in Host-Microbe Systems

1. Gabriel Penunuri
2. Pingting Wang
3. Russell Corbett-Detig
4. Shelbi L Russell

Reviewed by Arcadia Science

Unified knowledge-driven network inference from omics data

1. Pablo Rodriguez-Mier
2. Martin Garrido-Rodriguez
3. Attila Gabor
4. Julio Saez-Rodriguez

Reviewed by PREreview

Miniaturizing, Modifying, and Augmenting Nature’s Proteins with Raygun

1. Kapil Devkota
2. Daichi Shonai
3. Joey Mao
4. Scott Soderling
5. Rohit Singh

Reviewed by Arcadia Science

HyperMPNN – A general strategy to design thermostable proteins learned from hyperthermophiles

1. Moritz Ertelt
2. Phillip Schlegel
3. Max Beining
4. Leonard Kaysser
5. Jens Meiler
6. Clara T. Schoeder

Reviewed by Arcadia Science

demuxSNP: supervised demultiplexing scRNAseq using cell hashing and SNPs

1. Michael P. Lynch
2. Yufei Wang
3. Laurent Gatto
4. Aedin C. Culhane

Reviewed by GigaScience

stMMR: accurate and robust spatial domain identification from spatially resolved transcriptomics with multi-modal feature representation

1. Daoliang Zhang
2. Na Yu
3. Wenrui Li
4. Xue Sun
5. Qi Zou
6. Xiangyu Li
7. Zhiping Liu
8. Zhiyuan Yuan
9. Wei Zhang
10. Rui Gao

Reviewed by GigaScience

CAT Bridge: An Efficient Toolkit for Gene-Metabolite Association Mining from Multi-Omics Data

1. Bowen Yang
2. Tan Meng
3. Xinrui Wang
4. Jun Li
5. Shuang Zhao
6. Yingheng Wang
7. Shu Yi
8. Yi Zhou
9. Yi Zhang
10. Liang Li
11. Li Guo

Reviewed by GigaScience

Pan-tissue Transcriptome Analysis Reveals Sex-dimorphic Human Aging

1. Siqi Wang
2. Danyue Dong
3. Xin Li
4. Zefeng Wang

• Curated by eLife

  eLife Assessment

  This study examines age-related, sex-specific gene expression and alternative splicing in humans using the GTEx dataset. Solid evidence is provided to demonstrate that alternative splicing was affected by both sex and age across many tissues in this dataset. Although the authors performed comprehensive computational analyses with useful 'transcriptomic' changes with sex/age, they did not validate their findings with independent longitudinal datasets. This limits the wide impact of this study but can be used as a starting point to examine sex- and age differences in the transcriptome due to alternative splicing.

Reviewed by eLife

Metagenome-assembled genomes of Estonian Microbiome cohort reveal novel species and their links with prevalent diseases

1. Kateryna Pantiukh
2. Oliver Aasmets
3. Kertu Liis Krigul
4. Elin Org

Reviewed by Review Commons

ConvCGP: A Convolutional Neural Network to Predict Genotypic Values of Rice Traits from Compressed Genome-Wide Polymorphisms

1. Tanzila Islam
2. Chyon Hae Kim
3. Hiroyuki Shimono
4. Akio Kimura
5. Hiroyoshi Iwata

Reviewed by Arcadia Science