Evaluated articles

Discovery of highly active kynureninases for cancer immunotherapy through protein language model

1. Hyunuk Eom
2. Sukhwan Park
3. Kye Soo Cho
4. Jihyeon Lee
5. Hyunbin Kim
6. Stephanie Kim
7. Jinsol Yang
8. Young-Hyun Han
9. Juyong Lee
10. Chaok Seok
11. Myeong Sup Lee
12. Woon Ju Song
13. Martin Steinegger

Reviewed by Arcadia Science

Freshwater ‘microcroissants’ shed light on a novel higher-level clade within Trebouxiophyceae and reveal the genus Chlorolobion as a trebouxiophyte

1. Dovilė Barcytė
2. Ladislav Hodač
3. Marek Eliáš

Reviewed by Arcadia Science

Raman microscopy of cryofixed biological specimens for high-resolution and high-sensitivity chemical imaging

1. Kenta Mizushima
2. Yasuaki Kumamoto
3. Shoko Tamura
4. Masahito Yamanaka
5. Kentaro Mochizuki
6. Menglu Li
7. Syusuke Egoshi
8. Kosuke Dodo
9. Yoshinori Harada
10. Nicholas I. Smith
11. Mikiko Sodeoka
12. Hideo Tanaka
13. Katsumasa Fujita

Reviewed by Arcadia Science

A thin-film optogenetic visual prosthesis

1. Eric B Knudsen
2. Kara Zappitelli
3. Jennifer Brown
4. Jonathan Reeder
5. Kevin Sean Smith
6. Marat Rostov
7. Jaebin Choi
8. Amy Rochford
9. Nate Slager
10. Satoru K Miura
11. Kyle Rodgers
12. Ansel Reed
13. Yonatan R Lewis Israeli
14. Seton Shiraga
15. Kyung Jin Seo
16. Corey Wolin
17. Paul Dawson
18. Mohamed Eltaeb
19. Arvind Dasgupta
20. Max Rothman
21. Eugene Yoon
22. Paul Chong
23. Seleipiri Charles
24. Jay M. Stewart
25. Ruwan A Silva
26. Tyson Kim
27. Yifan Kong
28. Alan R Mardinly
29. Max Hodak

Reviewed by Arcadia Science

A fungi hotspot deep down the ocean: explaining the presence of Gjaerumia minor in Equatorial Pacific bathypelagic waters

1. Massimo C. Pernice
2. Irene Forn
3. Ramiro Logares
4. Ramon Massana

Reviewed by Arcadia Science

A treasure trove of 1,034 actinomycete genomes

1. Tue Sparholt Jørgensen
2. Omkar Mohite
3. Eva B Sterndorff
4. Maria Alvarez-Arevalo
5. Kai Blin
6. Thomas J Booth
7. Pep Charusanti
8. David Faurdal
9. Troels Ø Hansen
10. Matin Nuhamunada
11. Anna-Sophie Mourched
12. Bernhard Ø Palsson
13. Tilmann Weber

Reviewed by Arcadia Science

Temporal and spatial dynamics within the fungal microbiome of grape fermentation

1. Cristobal A. Onetto
2. Chris M. Ward
3. Steven Van Den Heuvel
4. Laura Hale
5. Kathleen Cuijvers
6. Anthony R. Borneman

Reviewed by Arcadia Science

Mast cell activation disrupts interactions between endothelial cells and pericytes during early life allergic asthma

1. Régis Joulia
2. Franz Puttur
3. Helen Stölting
4. William J. Traves
5. Lewis J. Entwistle
6. Anastasia Voitovich
7. Minerva Garcia Martín
8. May Al-Sahaf
9. Katie Bonner
10. Elizabeth Scotney
11. Philip L. Molyneaux
12. Richard J. Hewitt
13. Simone A. Walker
14. Laura Yates
15. Sejal Saglani
16. Clare M. Lloyd

Reviewed by Arcadia Science

A constraint-based framework to reconstruct interaction networks in microbial communities

1. Omid Oftadeh
2. Asli Sahin
3. Evangelia Vayena
4. Vassily Hatzimanikatis

Reviewed by Arcadia Science

CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans

1. Rachel Webster
2. Maria Quintana
3. Bin Yu
4. Stacey Fluke
5. Ran Kafri
6. W. Brent Derry

Reviewed by Arcadia Science

Evolution of novel sensory organs in fish with legs

1. Corey A.H. Allard
2. Amy L. Herbert
3. Stephanie P. Krueger
4. Qiaoyi Liang
5. Brittany L. Walsh
6. Andrew L. Rhyne
7. Allex N. Gourlay
8. Agnese Seminara
9. Maude W. Baldwin
10. David M. Kingsley
11. Nicholas W. Bellono

Reviewed by Arcadia Science

Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

1. Sasmita Panda
2. Yahani P Jayasinghe
3. Dhananjay D Shinde
4. Emilio Bueno
5. Amanda Stastny
6. Blake P Bertrand
7. Sujata S Chaudhari
8. Tammy Kielian
9. Felipe Cava
10. Donald R Ronning
11. Vinai C Thomas

• Curated by eLife

  eLife Assessment

  In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

Reviewed by eLife, Arcadia Science

Growing a Cystic Fibrosis-Relevant Polymicrobial Biofilm to Probe Community Phenotypes

1. Sarah Poirier
2. Fabrice Jean-Pierre

Reviewed by Arcadia Science

The LH receptor regulates hippocampal spatial memory and restores dendritic spine density in ovariectomized APP/PS1 AD mice

1. Megan Mey
2. Sabina Bhatta
3. Sneha Suresh
4. Luis Montero Labrador
5. Helen Piontkivska
6. Gemma Casadesus

Reviewed by Arcadia Science

High-volume, label-free imaging for quantifying single-cell dynamics in induced pluripotent stem cell colonies

1. Anthony J. Asmar
2. Zackery A. Benson
3. Adele P. Peskin
4. Joe Chalfoun
5. Mylene Simon
6. Michael Halter
7. Anne L. Plant

Reviewed by Arcadia Science

Phylogenomics reveals coincident divergence between giant host sea anemones and the clownfish adaptive radiation

1. Aurelien De Jode
2. Andrea M. Quattrini
3. Tommaso Chiodo
4. Marymegan Daly
5. Catherine S. McFadden
6. Michael L. Berumen
7. Christopher P. Meyer
8. Suzanne Mills
9. Ricardo Beldade
10. Aaron Bartholomew
11. Anna Scott
12. James D Reimer
13. Kensuke Yanagi
14. Takuma Fuji
15. Estefanía Rodríguez
16. Benjamin M. Titus

Reviewed by Arcadia Science

Excess microtubule and F-actin formation mediates shortening and loss of primary cilia in response to a hyperosmotic milieu

1. Hiroshi Otani
2. Ryota Nakazato
3. Kanae Koike
4. Keisuke Ohta
5. Koji Ikegami

Reviewed by Arcadia Science

Pinpointing the microbiota of tardigrades: What is really there?

1. Bartłomiej Surmacz
2. Daniel Stec
3. Monika Prus‐Frankowska
4. Mateusz Buczek
5. Łukasz Michalczyk
6. Piotr Łukasik

Reviewed by Arcadia Science