Evaluated articles

Beyond blast: enabling microbiologists to better extract literature, taxonomic distributions and gene neighbourhood information for protein families

1. Colbie J. Reed
2. Rémi Denise
3. Jacob Hourihan
4. Jill Babor
5. Marshall Jaroch
6. Maria Martinelli
7. Geoffrey Hutinet
8. Valérie de Crécy-Lagard

Reviewed by Arcadia Science

Novel Association of Lyme disease, Age, and Atopic Dermatitis

1. Brandon T. Lee
2. Sarah D. Galloway
3. Qingying Feng
4. Satu Strausz
5. Maia Shoham
6. Paige Hansen
7. Laughing Bear Torrez Dulgeroff
8. Grace Blacker
9. Ying Y. Yiu
10. Paul Mansfield
11. FinnGen
12. Atif Saleem
13. Eric Gars
14. Erin C. Sanders
15. Irving L. Weissman
16. Hanna M. Ollila
17. Michal Caspi Tal

Reviewed by Arcadia Science

Alternative splicing across the tree of life

1. Rebeca de la Fuente
2. Wladimiro Dı́az-Villanueva
3. Vicente Arnau
4. Andres Moya

• Curated by eLife

  eLife Assessment

  The authors examined the frequency of alternative splicing across prokaryotes and eukaryotes and found that the rate of alternative splicing varies with taxonomic groups and genome coding content. This solid work, based on nearly 1,500 high-quality genome assemblies, relies on a novel genome-scale metric that enables cross-species comparisons and that quantifies the extent to which coding sequences generate multiple mRNA transcripts via alternative splicing. This timely study provides an important basis for improving our general understanding of genome architecture and the evolution of life forms.

Reviewed by eLife, Arcadia Science

ADPKD-Causing Missense Variants in Polycystin-1 Disrupt Cell Surface Localization or Polycystin Channel Function

1. Kotdaji Ha
2. Gabriel B. Loeb
3. Meyeon Park
4. Mohona Gupta
5. Yukako Akiyama
6. Jillian Argiris
7. Aide Pinedo
8. Christine Haewon Park
9. Nadav Brandes
10. F. Ritu
11. Chun Jimmie Ye
12. Jeremy F. Reiter
13. Markus Delling

Reviewed by Arcadia Science

Contextual and combinatorial structure in sperm whale vocalisations

1. Pratyusha Sharma
2. Shane Gero
3. Roger Payne
4. David F. Gruber
5. Daniela Rus
6. Antonio Torralba
7. Jacob Andreas

Reviewed by Arcadia Science

A joint embedding of protein sequence and structure enables robust variant effect predictions

1. Lasse M. Blaabjerg
2. Nicolas Jonsson
3. Wouter Boomsma
4. Amelie Stein
5. Kresten Lindorff-Larsen

Reviewed by Arcadia Science

Engram reactivation mimics cellular signatures of fear

1. Rebecca L. Suthard
2. Ryan A. Senne
3. Michelle D. Buzharsky
4. Anh H. Diep
5. Angela Y. Pyo
6. Steve Ramirez

Reviewed by Arcadia Science

FAIR Header Reference genome: a TRUSTworthy standard

1. Adam Wright
2. Mark D Wilkinson
3. Christopher Mungall
4. Scott Cain
5. Stephen Richards
6. Paul Sternberg
7. Ellen Provin
8. Jonathan L Jacobs
9. Scott Geib
10. Daniela Raciti
11. Karen Yook
12. Lincoln Stein
13. David C Molik

Reviewed by Arcadia Science

Predicting phage-bacteria interactions at the strain level from genomes

1. Baptiste Gaborieau
2. Hugo Vaysset
3. Florian Tesson
4. Inès Charachon
5. Nicolas Dib
6. Juliette Bernier
7. Tanguy Dequidt
8. Héloïse Georjon
9. Olivier Clermont
10. Pascal Hersen
11. Laurent Debarbieux
12. Jean-Damien Ricard
13. Erick Denamur
14. Aude Bernheim

Reviewed by Arcadia Science

Chromatin profiling data indicate regulatory mechanisms for differentiation during development in the acoel Hofstenia miamia

1. Paul Bump
2. Kaitlyn Loubet-Senear
3. Sarah Arnold
4. Mansi Srivastava

Reviewed by Arcadia Science

Cell-selective proteomics reveal novel effectors secreted by an obligate intracellular bacterial pathogen

1. Allen G. Sanderlin
2. Hannah Kurka Margolis
3. Abigail F. Meyer
4. Rebecca L. Lamason

Reviewed by Arcadia Science

Arp2/3-dependent endocytosis ensures Cdc42 oscillations by removing Pak1-mediated negative feedback

1. Marcus A. Harrell
2. Ziyi Liu
3. Bethany F. Campbell
4. Olivia Chinsen
5. Tian Hong
6. Maitreyi Das

Reviewed by Arcadia Science

Bidirectional chemogenetic modulation of claustral activity causes altered cortical dynamics

1. Ryan Zahacy
2. Yonglie Ma
3. Ian R. Winship
4. Jesse Jackson
5. Allen W. Chan

Reviewed by Arcadia Science

Characterizing Human KIF1Bß Motor Activity by Single-Molecule Motility Assays and Caenorhabtidis elegans Genetics

1. Rei Iguchi
2. Tomoki Kita
3. Taisei Watanabe
4. Kyoko Chiba
5. Shinsuke Niwa

Reviewed by Arcadia Science

Learning orientation-invariant representations enables accurate and robust morphologic profiling of cells and organelles

1. James Burgess
2. Jeffrey J. Nirschl
3. Maria-Clara Zanellati
4. Sarah Cohen
5. Serena Yeung

Reviewed by Arcadia Science

TNF-alpha promotes cilia elongation via Mixed Lineage Kinases signaling

1. Amrita Kumari
2. Amada Caliz
3. Shashi Kant
4. Anastassiia Vertii

Reviewed by Arcadia Science

Integrated genomics provides insights for the evolution of the polyphosphate accumulation trait of Ca. Accumulibacter

1. Xiaojing Xie
2. Xuhan Deng
3. Liping Chen
4. Jing Yuan
5. Hang Chen
6. Chaohai Wei
7. Xianghui Liu
8. Stefan Wuertz
9. Guanglei Qiu

Reviewed by Arcadia Science

Dynamics of the viral community on the surface of a French smear-ripened cheese during maturation and persistence across production years

1. Thomas Paillet
2. Quentin Lamy-Besnier
3. Clarisse Figueroa
4. Marie-Agnès Petit
5. Eric Dugat-Bony

Reviewed by Rapid Reviews Infectious Diseases, Arcadia Science

Refinement of the “ Candidatus Accumulibacter” Genus Based on a Metagenomic Analysis of Biological Nutrient Removal (BNR) Pilot-Scale Plants Operated with Reduced Aeration

1. Rachel D. Stewart
2. Kevin S. Myers
3. Carly Amstadt
4. Matt Seib
5. Katherine D. McMahon
6. Daniel R. Noguera

Reviewed by Arcadia Science

Commensal skin bacteria exacerbate inflammation and delay skin healing

1. Veda D. Khadka
2. Laura Markey
3. Magalie Boucher
4. Tami D. Lieberman

Reviewed by Arcadia Science