Showing page 24 of 41 pages of list content

  1. Evolution of novel sensory organs in fish with legs

    This article has 11 authors:
    1. Corey A.H. Allard
    2. Amy L. Herbert
    3. Stephanie P. Krueger
    4. Qiaoyi Liang
    5. Brittany L. Walsh
    6. Andrew L. Rhyne
    7. Allex N. Gourlay
    8. Agnese Seminara
    9. Maude W. Baldwin
    10. David M. Kingsley
    11. Nicholas W. Bellono

    Reviewed by Arcadia Science

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  2. Recording Îł-secretase activity in living mouse brains

    This article has 9 authors:
    1. Steven S Hou
    2. Yuya Ikegawa
    3. Yeseo Kwon
    4. Natalia Wieckiewicz
    5. Mei CQ Houser
    6. Brianna Lundin
    7. Brian J Bacskai
    8. Oksana Berezovska
    9. Masato Maesako
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Hou and colleagues describe the the use of a previously characterized FRET sensor for use in determining gamma secretase activity in the brain of living mice. In an approach that targeted the sensor to neurons, they observe patterns of fluorescent sensor readout suggesting clustered regions of secretase activity. These results once validated would be valuable in the field of Alzheimer's Disease research, yet further validation of the approach is required, as the current evidence provided is inadequate to support the conclusions.

    Reviewed by eLife, Arcadia Science

    This article has 20 evaluationsAppears in 2 listsLatest version Latest activity
  3. Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity

    This article has 11 authors:
    1. Sasmita Panda
    2. Yahani P Jayasinghe
    3. Dhananjay D Shinde
    4. Emilio Bueno
    5. Amanda Stastny
    6. Blake P Bertrand
    7. Sujata S Chaudhari
    8. Tammy Kielian
    9. Felipe Cava
    10. Donald R Ronning
    11. Vinai C Thomas
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      In this useful study, the authors present convincing evidence linking the enzyme D-alanine-D-alanine ligase (Ddl), crucial for cell wall fortification, to organic acid exposure in Staphylococcus aureus. While it's established that organic acids impede bacterial growth, the researchers reveal a novel coping mechanism where S. aureus maintains elevated levels of D-alanine, the substrate for Ddl, to counteract this inhibition. This discovery illuminates a bacterial strategy for organic acid tolerance, offering new insights for microbiologists and potentially informing future antimicrobial approaches.

    Reviewed by eLife, Arcadia Science

    This article has 8 evaluationsAppears in 3 listsLatest version Latest activity
  4. Revealing global stoichiometry conservation architecture in cells from Raman spectral patterns

    This article has 6 authors:
    1. Ken-ichiro F Kamei
    2. Koseki J Kobayashi-Kirschvink
    3. Takashi Nozoe
    4. Hidenori Nakaoka
    5. Miki Umetani
    6. Yuichi Wakamoto
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This paper reports the fundamental finding of how Raman spectral patterns correlate with proteome profiles using Raman spectra of E. coli cells from different physiological conditions and found global stoichiometric regulation on proteomes. The authors' findings provide compelling evidence that stoichiometric regulation of proteomes is general through analysis of both bacterial and human cells. In the future, similar methodology can be applied on various tissue types and microbial species for studying proteome composition with Raman spectral patterns.

    Reviewed by eLife, Arcadia Science

    This article has 8 evaluationsAppears in 2 listsLatest version Latest activity
  5. Phylogenomics reveals coincident divergence between giant host sea anemones and the clownfish adaptive radiation

    This article has 16 authors:
    1. Aurelien De Jode
    2. Andrea M. Quattrini
    3. Tommaso Chiodo
    4. Marymegan Daly
    5. Catherine S. McFadden
    6. Michael L. Berumen
    7. Christopher P. Meyer
    8. Suzanne Mills
    9. Ricardo Beldade
    10. Aaron Bartholomew
    11. Anna Scott
    12. James D Reimer
    13. Kensuke Yanagi
    14. Takuma Fuji
    15. EstefanĂ­a RodrĂ­guez
    16. Benjamin M. Titus

    Reviewed by Arcadia Science

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  6. Disease-associated astrocyte epigenetic memory promotes CNS pathology

    This article has 24 authors:
    1. Hong-Gyun Lee
    2. Joseph M. Rone
    3. Zhaorong Li
    4. Camilo Faust Akl
    5. Seung Won Shin
    6. Joon-Hyuk Lee
    7. Lucas E. Flausino
    8. Florian Pernin
    9. Chun-Cheih Chao
    10. Kilian L. Kleemann
    11. Lena Srun
    12. Tomer Illouz
    13. Federico Giovannoni
    14. Marc Charabati
    15. Liliana M. Sanmarco
    16. Jessica E. Kenison
    17. Gavin Piester
    18. Stephanie E. J. Zandee
    19. Jack P. Antel
    20. Veit Rothhammer
    21. Michael A. Wheeler
    22. Alexandre Prat
    23. Iain C. Clark
    24. Francisco J. Quintana

    Reviewed by Arcadia Science

    This article has 3 evaluationsAppears in 1 listLatest version Latest activity