Evaluated articles

Mapping the human hematopoietic stem and progenitor cell hierarchy through integrated single-cell proteomics and transcriptomics

1. Benjamin Furtwängler
2. Nil Üresin
3. Sabrina Richter
4. Mikkel Bruhn Schuster
5. Despoina Barmpouri
6. Henrietta Holze
7. Anne Wenzel
8. Kirsten Grønbæk
9. Kim Theilgaard-Mönch
10. Fabian J. Theis
11. Erwin M. Schoof
12. Bo T Porse

Reviewed by Arcadia Science

Comprehensive Phenotyping of Extracellular Vesicles in Blood of Healthy Humans – Insights into Cellular Origin and Biological Variability

1. Marija Holcar
2. Ivica Marić
3. Tobias Tertel
4. Katja Goričar
5. Urška Čegovnik Primožič
6. Darko Černe
7. Bernd Giebel
8. Metka Lenassi

Reviewed by Arcadia Science

Genomic Signatures of Domestication in a Fungus Obligately Farmed by Leafcutter Ants

1. Caio A Leal-Dutra
2. Joel Vizueta
3. Tobias Baril
4. Pepijn W Kooij
5. Asta Rødsgaard-Jørgensen
6. Benjamin H Conlon
7. Daniel Croll
8. Jonathan Z Shik

Reviewed by Arcadia Science

Addition of Soil Protists Enhances Performance of Agrochemical Seed Treatments

1. Christopher J. Hawxhurst
2. Travis McClure
3. Daniel Kirk
4. Mikhael Shor
5. Daniel J. Gage
6. Leslie M. Shor

Reviewed by Arcadia Science

Limitations of current machine learning models in predicting enzymatic functions for uncharacterized proteins

1. Valérie de Crécy-Lagard
2. Raquel Dias
3. Nick Sexson
4. Iddo Friedberg
5. Yifeng Yuan
6. Manal A Swairjo

Reviewed by Arcadia Science

GenomeDelta: detecting recent transposable element invasions without repeat library

1. Riccardo Pianezza
2. Anna Haider
3. Robert Kofler

Reviewed by Arcadia Science

Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)

1. Kara Schmidlin
2. C. Brandon Ogbunugafor
3. Alexander Sastokas
4. Kerry Geiler-Samerotte

Reviewed by Arcadia Science

Artificial selection improves pollutant degradation by bacterial communities

1. Flor I. Arias-Sánchez
2. Björn Vessman
3. Alice Haym
4. Géraldine Alberti
5. Sara Mitri

Reviewed by Arcadia Science

Structural characterization of DNA-binding domain of essential mammalian protein TTF 1

1. Gajender Singh
2. Abhinetra Jagdish Bhopale
3. Saloni Khatri
4. Prashant Prakash
5. Rajnish Kumar
6. Sukh Mahendra Singh
7. Samarendra Kumar Singh

Reviewed by Arcadia Science

Ixodes ricinus bites promote allergic skin inflammation and intestinal tuft and mast cell expansion in mice

1. Juan Manuel Leyva-Castillo
2. Maria Strakosha
3. Sophia E.M. Smith
4. Daniela Vega-Mendoza
5. Megan Elkins
6. Janet Chou
7. Peter Vogel
8. Nathalie Boulanger

Reviewed by Arcadia Science

Coherent Raman microscopy detects nucleolar defects through amide I peak shifts originating from β-sheets: an application to visualizing ongoing cellular senescence

1. Shigeo Ishibashi
2. Akihito Inoko
3. Yuki Oka
4. Philippe Leproux
5. Hideaki Kano

Reviewed by Arcadia Science

Hyperspectral imaging for chloroplast movement detection

1. Paweł Hermanowicz
2. Justyna Łabuz

Reviewed by Arcadia Science

Effect of truffle extracts on growth of Chlorella vulgaris

1. Anfisa A. Vlasova
2. Olga E. Lipatova
3. Alexander Y. Belyshenko
4. Elena I. Martynova
5. Natalia A. Imidoeva
6. Tamara Y. Telnova
7. Ekaterina V. Malygina
8. Maria M. Morgunova
9. Maria E. Dmitrieva
10. Victoria N. Shelkovnikova
11. Sophia S. Shashkina
12. Tatiana N. Vavilina
13. Denis V. Axenov-Gribanov

Reviewed by Arcadia Science

Delineating markers of disease-disease interaction: a systematic methodology and its application to multiple diabetes-helminth cohorts

1. Nilesh Anantha Subramanian
2. Philge Philip
3. Anuradha Rajamanickam
4. Nathella Pavan Kumar
5. Subash Babu
6. Manikandan Narayanan

Reviewed by Arcadia Science

Essential Roles of RodA Peptidoglycan Polymerase and PBP2 Transpeptidase in Expression of Cell Wall-Spanning Supramolecular Organelles and Modulating Salmonella Virulence

1. Anne C. Doble
2. Bethany C Gollan
3. John Clark-Corrigall
4. David M. Bulmer
5. Richard A Daniel
6. Pietro Mastroeni
7. C. M. Anjam Khan

Reviewed by Arcadia Science

The actomyosin system is essential for the integrity of the endosomal system in bloodstream form Trypanosoma brucei

1. Fabian Link
2. Sisco Jung
3. Xenia Malzer
4. Felix Zierhut
5. Antonia Konle
6. Alyssa Borges
7. Christopher Batters
8. Monika Weiland
9. Mara Poellmann
10. An Binh Nguyen
11. Johannes Kullmann
12. Claudia Veigel
13. Markus Engstler
14. Brooke Morriswood

• Curated by eLife

  eLife assessment

  This important study builds on a previous publication, demonstrating that T. brucei has a continuous endomembrane system, which probably facilitates high rates of endocytosis. Using a range of cutting-edge approaches, the authors present compelling evidence that an actomyosin system, with the myosin TbMyo1 as an active molecular motor, is localized close to and can associate with the endosomal system in the bloodstream form of Trypanosoma brucei. It shows convincingly that both actin and Myo I play a role in the organization and integrity of the endosomal system: both RNAi-mediated depletion of Myo1, and treatment of the cells with latrunculin A resulted in endomembrane disruption. This work should be of interest to cell biologists and microbiologists working on the cytoskeleton, and unicellular eukaryotes.

Reviewed by eLife, Arcadia Science

Estimates of molecular convergence reveal genes with intermediate pleiotropy underlying adaptive variation across teleost fish

1. Agneesh Barua
2. Malvika Srivastava
3. Brice Beinsteiner
4. Vincent Laudet
5. Marc Robinson-Rechavi

Reviewed by Arcadia Science

ESPRESSO: Spatiotemporal omics based on organelle phenotyping

1. Lorenzo Scipioni
2. Giulia Tedeschi
3. Mariana Navarro
4. Yunlong Jia
5. Scott Atwood
6. Jennifer A. Prescher
7. Michelle Digman

Reviewed by Arcadia Science

Shotgun metagenomic analysis of the skin mucus bacteriome of the common carp ( Cyprinus carpio )

1. Márton Papp
2. Adrienn Gréta Tóth
3. Sára Ágnes Nagy
4. Károly Erdélyi
5. Gergely Maróti
6. Niamh Cox
7. László Czikk
8. Máté Katics
9. László Békési
10. Norbert Solymosi

Reviewed by PREreview, Arcadia Science

Time-resolved mitochondrial-focused screening identifies regulatory components of oxidative metabolism

1. Marcos Zamora-Dorta
2. Sara Laine-Menéndez
3. David Abia
4. Pilar González-García
5. Luis C. López
6. Paula Fernández-Montes Díaz
7. Enrique Calvo
8. Jesús Vázquez
9. José Antonio Enríquez
10. Eduardo Balsa

Reviewed by Arcadia Science