Evaluated articles

ADAR1 orchestrates the ZBP1-mediated PANoptosis and heart transplant rejection

1. Haitao Lu
2. Jifu Jiang
3. Xuyan Huang
4. Aaron Haig
5. Lakshman Gunaratman
6. Anthony M. Jevnikar
7. Zhu-Xu Zhang

Reviewed by Arcadia Science

Two newly cultivated eukaryotrophic flagellates represent distinct anaerobic lineages within Rhizaria

1. Yana Eglit
2. Maggie Lawton
3. Alastair G.B. Simpson
4. Ryan M.R. Gawryluk

Reviewed by Arcadia Science

Latent infection of an active giant endogenous virus in a unicellular green alga

1. Maria P. Erazo-Garcia
2. Uri Sheyn
3. Zachary K. Barth
4. Rory J. Craig
5. Petronella Wessman
6. Abdeali M. Jivaji
7. W. Keith Ray
8. Maria Svensson-Coelho
9. Charlie K. Cornwallis
10. Karin Rengefors
11. Corina P. D. Brussaard
12. Mohammad Moniruzzaman
13. Frank O. Aylward

Reviewed by Arcadia Science

A 3D-printed handheld device for quick citrus tissue lysis and nucleic acid extraction

1. Chia-Wei Liu
2. Brent Kalish
3. Sohrab Bodaghi
4. Georgios Vidalakis
5. Hideaki Tsutsui

Reviewed by Arcadia Science

Point set registration for combining fluorescence microscopy methods

1. Ivo Severins
2. Chirlmin Joo
3. John van Noort

Reviewed by Arcadia Science

Description of a novel extremophile green algae, Chlamydomonas pacifica, and its potential as a biotechnology host

1. João Vitor Dutra Molino
2. Aaron Oliver
3. Harish Sethuram
4. Kalisa Kang
5. Barbara Saucedo
6. Crisandra Jade Diaz
7. Abhishek Gupta
8. Lee Jong Jen
9. Yasin Torres-tiji
10. Nora Hidasi
11. Amr Badary
12. Hunter Jenkins
13. Francis J. Fields
14. Ryan Simkovsky
15. Stephen Mayfield

Reviewed by Arcadia Science

Assessing the ability of ChatGPT to extract natural product bioactivity and biosynthesis data from publications

1. Thomas L. Kalmer
2. Christine Mae F. Ancajas
3. Zihao Cheng
4. Abiodun S. Oyedele
5. Hunter L. Davis
6. Allison S. Walker

Reviewed by Arcadia Science

Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution

1. Falko Fuhrmann
2. Felix C. Nebeling
3. Fabrizio Musacchio
4. Manuel Mittag
5. Stefanie Poll
6. Monika Müller
7. Eleonora Ambrad Giovannetti
8. Michael Maibach
9. Barbara Schaffran
10. Emily Burnside
11. Ivy Chi Wai Chan
12. Alex Simon Lagurin
13. Nicole Reichenbach
14. Sanjeev Kaushalya
15. Hans Fried
16. Stefan Linden
17. Gabor C. Petzold
18. Gaia Tavosanis
19. Frank Bradke
20. Martin Fuhrmann

Reviewed by Arcadia Science

Phyloformer: Fast, Accurate, and Versatile Phylogenetic Reconstruction with Deep Neural Networks

1. Luca Nesterenko
2. Luc Blassel
3. Philippe Veber
4. Bastien Boussau
5. Laurent Jacob

Reviewed by Arcadia Science

Productive mRNA Chromatin Escape is Promoted by PRMT5 Methylation of SNRPB

1. Joseph D. DeAngelo
2. Maxim I. Maron
3. Jacob S. Roth
4. Aliza M. Silverstein
5. Varun Gupta
6. Stephanie Stransky
7. Joel Basken
8. Joey Azofeifa
9. Simone Sidoli
10. Matthew J. Gamble
11. David Shechter

Reviewed by Arcadia Science

Human birth tissue products as a non-opioid medicine to inhibit post-surgical pain

1. Chi Zhang
2. Qian Huang
3. Neil C Ford
4. Nathachit Limjunyawong
5. Qing Lin
6. Fei Yang
7. Xiang Cui
8. Ankit Uniyal
9. Jing Liu
10. Megha Mahabole
11. Hua He
12. Xuewei Wang
13. Irina Duff
14. Yiru Wang
15. Jieru Wan
16. Guangwu Zhu
17. Srinivasa N Raja
18. Hongpeng Jia
19. Dazhi Yang
20. Xinzhong Dong
21. Xu Cao
22. Scheffer C Tseng
23. Shaoqiu He
24. Yun Guan

• Curated by eLife

  eLife Assessment

  The authors provide convincing data that identify a novel, non-opioid biologic from human birth tissue products with anti-nociceptive properties in a preclinical mouse model of surgical pain. This important study highlights the potential use of naturally derived biologics from human birth tissues as safe and sustainable pain treatment options that do not possess the adverse side effects associated with opioids and synthetic pharmaceuticals. Whether these results will translate to the clinic remains to be seen, nevertheless, these preclinical findings are promising.

Reviewed by eLife, Arcadia Science

Unique ultrastructural organization of human rod photoreceptors

1. Tylor R. Lewis
2. Natalia V. Klementieva
3. Sebastien Phan
4. Carson M. Castillo
5. Keun-Young Kim
6. Lauren Y. Cao
7. Mark H. Ellisman
8. Vadim Y. Arshavsky
9. Oleg Alekseev

Reviewed by Arcadia Science

The membrane domains of mammalian adenylyl cyclases are lipid receptors

1. Marius Landau
2. Sherif Elsabbagh
3. Harald Gross
4. Adrian CD Fuchs
5. Anita CF Schultz
6. Joachim E Schultz

• Curated by eLife

  eLife Assessment

  This manuscript describes an important study of a new lipid-mediated regulation mechanism of adenylyl cyclases. The biochemical evidence provided is convincing and will trigger more research in this mechanism. This manuscript will be of interest to all scientists working on lipid regulation and adenylyl cyclases.

Reviewed by eLife, Arcadia Science

Peptipedia v2.0: A peptide sequence database and user-friendly web platform. A major update

1. Gabriel Cabas-Mora
2. Anamaría Daza
3. Nicole Soto-García
4. Valentina Garrido
5. Diego Alvarez
6. Marcelo Navarrete
7. Lindybeth Sarmiento-Varón
8. Julieta H. Sepúlveda Yañez
9. Mehdi D. Davari
10. Frederic Cadet
11. Álvaro Olivera-Nappa
12. Roberto Uribe-Paredes
13. David Medina-Ortiz

Reviewed by Arcadia Science

Raspberry Pi Powered Imaging for Plant Phenotyping

1. Jose C. Tovar
2. J. Steen Hoyer
3. Andy Lin
4. Allison Tielking
5. Monica Tessman
6. Michael Miller
7. Steven T. Callen
8. S. Elizabeth Castillo
9. Noah Fahlgren
10. James C. Carrington
11. Dmitri A. Nusinow
12. Malia A. Gehan

Reviewed by Arcadia Science

Direct inference of the distribution of fitness effects of spontaneous mutations from recombinant inbred C. elegans mutation accumulation lines

1. Timothy A. Crombie
2. Moein Rajaei
3. Ayush S. Saxena
4. Lindsay M. Johnson
5. Sayran Saber
6. Robyn E. Tanny
7. José Miguel Ponciano
8. Erik C. Andersen
9. Juannan Zhou
10. Charles F. Baer

Reviewed by Arcadia Science

Ciliary biology intersects autism and congenital heart disease

1. Nia Teerikorpi
2. Kate E. McCluskey
3. Ethel Bader
4. Micaela C. Lasser
5. Sheng Wang
6. Catherine H. Nguyen
7. James D. Schmidt
8. Elina Kostyanovskaya
9. Nawei Sun
10. Jeanselle Dea
11. Tomasz J. Nowakowski
12. A. Jeremy Willsey
13. Helen Rankin Willsey

Reviewed by Arcadia Science

The Rich Evolutionary History of the Reactive Oxygen Species Metabolic Arsenal Shapes Its Mechanistic Plasticity at the Onset of Metazoan Regeneration

1. Aurore Vullien
2. Aldine R Amiel
3. Loeiza Baduel
4. Dilara Diken
5. Cécile Renaud
6. Gabriel Krasovec
7. Michel Vervoort
8. Eric Röttinger
9. Eve Gazave

Reviewed by Arcadia Science

Development of a highly active engineered PETase enzyme for polyester degradation

1. Shapla Bhattacharya
2. Rossella Castagna
3. Hajar Estiri
4. Toms Upmanis
5. Andrea Ricci
6. Alfonso Gautieri
7. Emilio Parisini

Reviewed by Arcadia Science

Rapid protein evolution by few-shot learning with a protein language model

1. Kaiyi Jiang
2. Zhaoqing Yan
3. Matteo Di Bernardo
4. Samantha R. Sgrizzi
5. Lukas Villiger
6. Alisan Kayabolen
7. Byungji Kim
8. Josephine K. Carscadden
9. Masahiro Hiraizumi
10. Hiroshi Nishimasu
11. Jonathan S. Gootenberg
12. Omar O. Abudayyeh

Reviewed by Arcadia Science