Evaluated articles

CELEBRIMBOR: Pangenomes from metagenomes

1. Joel Hellewell
2. Samuel T. Horsfield
3. Johanna von Wachsmann
4. Tatiana Gurbich
5. Robert D. Finn
6. Zamin Iqbal
7. Leah W. Roberts
8. John A. Lees

Reviewed by Arcadia Science

Genes in Humans and Mice: Insights from Deep learning of 777K Bulk Transcriptomes

1. Zheng Su
2. Mingyan Fang
3. Andrei Smolnikov
4. Fatemeh Vafaee
5. Marcel E. Dinger
6. Emily C. Oates

Reviewed by Arcadia Science

An evolutionary cell biology perspective into the diverging mechanisms of clathrin-mediated endocytosis in dikarya fungi

1. Andrea Picco
2. Christopher P. Toret
3. Anne-Sophie Rivier-Cordey
4. Marko Kaksonen

Reviewed by Arcadia Science

The Evolutionary Origins and Ancestral Features of Septins

1. Samed Delic
2. Brent Shuman
3. Shoken Lee
4. Shirin Bahmanyar
5. Michelle Momany
6. Masayuki Onishi

Reviewed by Arcadia Science

Machine Learning Assisted Spectral Fingerprinting for Immune Cell Phenotyping

1. Aceer Nadeem
2. Sarah Lyons
3. Aidan Kindopp
4. Amanda Jamieson
5. Daniel Roxbury

Reviewed by Arcadia Science

Evaluating generalizability of artificial intelligence models for molecular datasets

1. Yasha Ektefaie
2. Andrew Shen
3. Daria Bykova
4. Maximillian Marin
5. Marinka Zitnik
6. Maha Farhat

Reviewed by Arcadia Science

Assessment of Gene Set Enrichment Analysis using curated RNA-seq-based benchmarks

1. Julián Candia
2. Luigi Ferrucci

Reviewed by Arcadia Science

Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling, and cloud-native open-source tools

1. Dan Biderman
2. Matthew R Whiteway
3. Cole Hurwitz
4. Nicholas Greenspan
5. Robert S Lee
6. Ankit Vishnubhotla
7. Richard Warren
8. Federico Pedraja
9. Dillon Noone
10. Michael Schartner
11. Julia M Huntenburg
12. Anup Khanal
13. Guido T Meijer
14. Jean-Paul Noel
15. Alejandro Pan-Vazquez
16. Karolina Z Socha
17. Anne E Urai
18. The International Brain Laboratory
19. John P Cunningham
20. Nathaniel B Sawtell
21. Liam Paninski

Reviewed by Arcadia Science

Evolutionary rescue of spherical mreB deletion mutants of the rod-shape bacterium Pseudomonas fluorescens SBW25

1. Paul Richard J Yulo
2. Nicolas Desprat
3. Monica L Gerth
4. Barbara Ritzl-Rinkenberger
5. Andrew D Farr
6. Yunhao Liu
7. Xue-Xian Zhang
8. Michael Miller
9. Felipe Cava
10. Paul B Rainey
11. Heather L Hendrickson

• Curated by eLife

  eLife Assessment

  This important study combines convincing evolution experiments with molecular and genetic techniques to study how a genetic lesion in MreB that causes rod-shaped cells to become spherical, with concomitant deleterious fitness effects, can be rescued by natural selection. The detailed mechanistic investigation increases our understanding of how mreB contributes to cell wall synthesis and shows how compensatory mutations may reestablish its homogeneity.

Reviewed by eLife, Arcadia Science

Predicting microbial growth conditions from amino acid composition

1. Tyler P. Barnum
2. Alexander Crits-Christoph
3. Michael Molla
4. Paul Carini
5. Henry H. Lee
6. Nili Ostrov

Reviewed by Arcadia Science

Dueling Endogenous Viral-Like Sequences Control Synaptic Plasticity

1. P. Githure M’Angale
2. Adrienne Lemieux
3. Yumeng Liu
4. Jasmine Graslie
5. Shuhao Wang
6. Alfred Simkin
7. Vivian Budnik
8. Brian A. Kelch
9. Travis Thomson

Reviewed by Arcadia Science

The Diverse Evolutionary Histories of Domesticated Metaviral Capsid Genes in Mammals

1. William S Henriques
2. Janet M Young
3. Artem Nemudryi
4. Anna Nemudraia
5. Blake Wiedenheft
6. Harmit S Malik

Reviewed by Arcadia Science

Clonal-aggregative multicellularity entrained by salinity in one of the closest relative of animals

1. Núria Ros-Rocher
2. Josean Reyes-Rivera
3. Uzuki Horo
4. Yeganeh Foroughijabbari
5. Chantal Combredet
6. Ben T. Larson
7. Maxwell C. Coyle
8. Erik A. T. Houtepen
9. Mark J. A. Vermeij
10. Jacob L. Steenwyk
11. Thibaut Brunet

Reviewed by Arcadia Science

Preeclampsia in mice carrying fetuses with APOL1 risk variants

1. Teruhiko Yoshida
2. Khun Zaw Latt
3. Shashi Shrivastav
4. Huiyan Lu
5. Kimberly J. Reidy
6. Jennifer R. Charlton
7. Yongmei Zhao
8. Cheryl A. Winkler
9. Sandra E. Reznik
10. Avi Z. Rosenberg
11. Jeffrey B. Kopp

Reviewed by Arcadia Science

Mu opioid receptors gate the locus coeruleus pain generator

1. Makenzie R. Norris
2. Chao-Cheng Kuo
3. Samantha S. Dunn
4. Jenny R. Kim
5. Léa J. Becker
6. Gustavo Borges
7. Loc V. Thang
8. Kyle E. Parker
9. Jordan G. McCall

Reviewed by Arcadia Science

Microglia contact cerebral vasculature through gaps between astrocyte endfeet

1. Gary P. Morris
2. Catherine G. Foster
3. Brad A. Sutherland
4. Søren Grubb

Reviewed by Arcadia Science

Menopause has not evolved as a general trait in mammals: A response to ‘Do mammals have menopause?’

1. Simon N. Chapman
2. Samuel Ellis
3. Mirkka Lahdenperä
4. Darren P. Croft
5. Virpi Lummaa

Reviewed by Arcadia Science

Behavioral sequences across multiple animal species in the wild share common structural features

1. Pranav Minasandra
2. Emily M Grout
3. Katrina Brock
4. Margaret C Crofoot
5. Vlad Demartsev
6. Andrew S Gersick
7. Ben T Hirsch
8. Kay E Holekamp
9. Lily Johnson-Ulrich
10. Amlan Nayak
11. Josué Ortega
12. Marie A Roch
13. Eli D Strauss
14. Ariana Strandburg-Peshkin

Reviewed by Arcadia Science

Pseudo-spectral angle mapping for automated pixel-level analysis of highly multiplexed tissue image data

1. Madeleine S. Durkee
2. Junting Ai
3. Gabriel Casella
4. Thao Cao
5. Anthony Chang
6. Ariel Halper-Stromberg
7. Bana Jabri
8. Marcus R. Clark
9. Maryellen L. Giger

Reviewed by Arcadia Science

Chlomito: a novel tool for precise elimination of organelle genome contamination in nuclear genome assemblies

1. Wei Song
2. Chong Li
3. Yanming Lu
4. Dawei Shen
5. Yunxiao Jia
6. Yixin Huo
7. Weilan Piao
8. Hua Jin

Reviewed by Arcadia Science