Showing page 35 of 72 pages of list content

  1. Human neural tube morphogenesis in vitro by geometric constraints

    This article has 11 authors:
    1. Eyal Karzbrun
    2. Aimal H. Khankhel
    3. Heitor C. Megale
    4. Stella M. K. Glasauer
    5. Yofiel Wyle
    6. George Britton
    7. Aryeh Warmflash
    8. Kenneth S. Kosik
    9. Eric D. Siggia
    10. Boris I. Shraiman
    11. Sebastian J. Streichan

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development

    This article has 11 authors:
    1. Ragini Phansalkar
    2. Josephine Krieger
    3. Mingming Zhao
    4. Sai Saroja Kolluru
    5. Robert C. Jones
    6. Stephen R Quake
    7. Irving Weissman
    8. Daniel Bernstein
    9. Virginia D. Winn
    10. Gaetano D’Amato
    11. Kristy Red-Horse
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      This study investigates the relationships of endothelial cells that comprise the coronary vessels of the heart in mouse and humans. Starting from the knowledge that two sources of progenitor cells contribute to the coronary vessels, the work shows that adult coronary endothelial cells do not retain expression memory of their source, nor do they respond differently to cardiac injury. Finally, human datasets were generated and compared to mouse to show overall strong similarity between the species in coronary endothelial cell subtypes, suggesting that mouse is a relevant model for translation to human treatments and therapies.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their names with the authors.)

    Reviewed by eLife, preLights

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  3. Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

    This article has 17 authors:
    1. C. C. Bain
    2. D. A. Gibson
    3. N. J. Steers
    4. K. Boufea
    5. P. A. Louwe
    6. C. Doherty
    7. V. González-Huici
    8. R. Gentek
    9. M. Magalhaes-Pinto
    10. T. Shaw
    11. M. Bajénoff
    12. C. Bénézech
    13. S. R. Walmsley
    14. D. H. Dockrell
    15. P. T. K. Saunders
    16. N. N. Batada
    17. S. J. Jenkins

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. Mechanism of cell polarisation and first lineage segregation in the human embryo

    This article has 20 authors:
    1. Meng Zhu
    2. Marta N. Shahbazi
    3. Angel Martin
    4. Chuanxin Zhang
    5. Berna Sozen
    6. Mate Borsos
    7. Rachel S. Mandelbaum
    8. Richard J. Paulson
    9. Matteo A. Mole
    10. Marga Esbert
    11. Richard T. Scott
    12. Alison Campbell
    13. Simon Fishel
    14. Viviana Gradinaru
    15. Han Zhao
    16. Keliang Wu
    17. Zijiang Chen
    18. Emre Seli
    19. Maria J. de los Santos
    20. Magdalena Zernicka-Goetz

    Reviewed by preLights

    This article has 1 evaluationAppears in 1 listLatest version Latest activity