Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages

  1. C. C. Bain
  2. D. A. Gibson
  3. N. J. Steers
  4. K. Boufea
  5. P. A. Louwe
  6. C. Doherty
  7. V. González-Huici
  8. R. Gentek
  9. M. Magalhaes-Pinto
  10. T. Shaw
  11. M. Bajénoff
  12. C. Bénézech
  13. S. R. Walmsley
  14. D. H. Dockrell
  15. P. T. K. Saunders
  16. N. N. Batada
  17. S. J. Jenkins

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Abstract

Peritoneal macrophages exhibit sexually dimorphic transcriptional profiles, functional capacity, and replenishment kinetics.

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  1. Version published to 10.1126/sciimmunol.abc4466
  3. Version published to 10.1101/837336v1 on bioRxiv