Evaluated articles

Alteration of long- and short-term hematopoietic stem cell ratio causes myeloid-biased hematopoiesis

1. Katsuyuki Nishi
2. Taro Sakamaki
3. Akiomi Nagasaka
4. Kevin Shuolong Kao
5. Kay Sadaoka
6. Masahide Asano
7. Nobuyuki Yamamoto
8. Akifumi Takaori-Kondo
9. Masanori Miyanishi

• Curated by eLife

  eLife Assessment

  This manuscript provides valuable insights into the heterogeneity of hematopoietic stem cells and age-associated myeloid-biased hematopoiesis. While several aspects of the study are intriguing and merit further investigation, the current results remain incomplete and additional data are necessary to substantiate the conclusions. Some of the methods and data analyses partially support the claims.

Reviewed by eLife, preLights

How the liver contributes to stomach warming in the endothermic white shark Carcharodon carcharias

1. David C. Bernvi
2. Geremy Cliff

Reviewed by preLights

Expressive modeling and fast simulation for dynamic compartments

1. Till Köster
2. Philipp Henning
3. Tom Warnke
4. Adelinde Uhrmacher

Reviewed by preLights

Temporal constraints on enhancer usage shape the regulation of limb gene transcription

1. Raquel Rouco
2. Antonella Rauseo
3. Guillaume Sapin
4. Olimpia Bompadre
5. Fabrice Darbellay
6. Guillaume Andrey

Reviewed by preLights

OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide

1. Hugo Sepulveda
2. Xiang Li
3. Leo J. Arteaga-Vazquez
4. Isaac F. López-Moyado
5. Melina Brunelli
6. Lot Hernández-Espinosa
7. Xiaojing Yue
8. J. Carlos Angel
9. Caitlin Brown
10. Zhen Dong
11. Natasha Jansz
12. Fabio Puddu
13. Aurélie Modat
14. Jamie Scotcher
15. Páidí Creed
16. Patrick H. Kennedy
17. Cindy Manriquez-Rodriguez
18. Samuel A. Myers
19. Robert Crawford
20. Geoffrey J. Faulkner
21. Anjana Rao

Reviewed by preLights

Transcriptional profiling of human brain cortex identifies novel lncRNA-mediated networks dysregulated in amyotrophic lateral sclerosis

1. Alessandro Palma
2. Monica Ballarino

Reviewed by preLights

Structural basis of respiratory complexes adaptation to cold temperatures

1. Young-Cheul Shin
2. Pedro Latorre-Muro
3. Amina Djurabekova
4. Oleksii Zdorevskyi
5. Christopher F. Bennett
6. Nils Burger
7. Kangkang Song
8. Chen Xu
9. Vivek Sharma
10. Maofu Liao
11. Pere Puigserver

Reviewed by preLights

Clusters of lineage-specific genes are anchored by ZNF274 in repressive perinucleolar compartments

1. Martina Begnis
2. Julien Duc
3. Sandra Offner
4. Delphine Grun
5. Shaoline Sheppard
6. Olga Rosspopoff
7. Didier Trono

Reviewed by preLights

RIPK3 coordinates RHIM domain-dependent inflammatory transcription in neurons

1. Sigal B. Kofman
2. Lan H. Chu
3. Joshua M. Ames
4. Suny Dayane Chavarria
5. Katrina Lichauco
6. Brian P. Daniels
7. Andrew Oberst

Reviewed by preLights

Synergistic olfactory processing for social plasticity in desert locusts

1. Inga Petelski
2. Yannick Günzel
3. Sercan Sayin
4. Susanne Kraus
5. Einat Couzin-Fuchs

Reviewed by preLights

A long non-coding RNA at the cortex locus controls adaptive colouration in butterflies

1. Luca Livraghi
2. Joseph J. Hanly
3. Elizabeth Evans
4. Charlotte J. Wright
5. Ling S. Loh
6. Anyi Mazo-Vargas
7. Kiana Kamrava
8. Alexander Carter
9. Eva S.M. van der Heijden
10. Robert D. Reed
11. Riccardo Papa
12. Chris D. Jiggins
13. Arnaud Martin

Reviewed by preLights

Actin polymerization drives lumen formation in a human epiblast model

1. Dhiraj Indana
2. Andrei Zakharov
3. Youngbin Lim
4. Alexander R. Dunn
5. Nidhi Bhutani
6. Vivek B. Shenoy
7. Ovijit Chaudhuri

Reviewed by preLights

Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion

1. David Anaguano
2. Opeoluwa Adewale-Fasoro
3. Grace W. Vick
4. Sean Yanik
5. James Blauwkamp
6. Manuel A. Fierro
7. Sabrina Absalon
8. Prakash Srinivasan
9. Vasant Muralidharan

Reviewed by preLights

A complex Plasmodium falciparum cryptotype circulating at low frequency across the African continent

1. Olivo Miotto
2. Alfred Amambua-Ngwa
3. Lucas Amenga-Etego
4. Muzamil M Abdel Hamid
5. Ishag Adam
6. Enoch Aninagyei
7. Tobias Apinjoh
8. Gordon A Awandare
9. Philip Bejon
10. Gwladys I Bertin
11. Marielle Bouyou-Akotet
12. Antoine Claessens
13. David J Conway
14. Umberto D’Alessandro
15. Mahamadou Diakite
16. Abdoulaye Djimdé
17. Arjen M Dondorp
18. Patrick Duffy
19. Rick M Fairhurst
20. Caterina I Fanello
21. Anita Ghansah
22. Deus Ishengoma
23. Mara Lawniczak
24. Oumou Maïga-Ascofaré
25. Sarah Auburn
26. Anna Rosanas-Urgell
27. Varanya Wasakul
28. Nina FD White
29. Jacob Almagro-Garcia
30. Richard D Pearson
31. Sonia Goncalves
32. Cristina Ariani
33. Zbynek Bozdech
34. William Hamilton
35. Victoria Simpson
36. Dominic P Kwiatkowski

Reviewed by preLights

Spatial transcriptomics elucidates medulla niche supporting germinal center response in myasthenia gravis thymoma

1. Yoshiaki Yasumizu
2. Makoto Kinoshita
3. Martin Jinye Zhang
4. Daisuke Motooka
5. Koichiro Suzuki
6. Daisuke Okuzaki
7. Satoshi Nojima
8. Soichiro Funaki
9. Yasushi Shintani
10. Naganari Ohkura
11. Eiichi Morii
12. Tatsusada Okuno
13. Hideki Mochizuki

Reviewed by preLights

Holimap: an accurate and efficient method for solving stochastic gene network dynamics

1. Chen Jia
2. Ramon Grima

Reviewed by preLights

Postural adaptations may contribute to the unique locomotor energetics seen in hopping kangaroos

1. Lauren Thornton
2. Taylor Dick
3. John R Hutchinson
4. Glen A Lichtwark
5. Craig P McGowan
6. Jonas Rubenson
7. Alexis Wiktorowicz-Conroy
8. Christofer J Clemente

• Curated by eLife

  eLife Assessment

  This valuable biomechanical analysis of kangaroo kinematics and kinetics across a range of hopping speeds and masses is a step towards understanding a long-standing problem in locomotion biomechanics: the mechanism for how kangaroos, unlike other mammals, can increase hopping speed without a concomitant increase in metabolic cost. The authors convincingly demonstrate that changes in kangaroo posture with speed increase tendon stress/strain and hence elastic energy storage/return. This greater tendon elastic energy storage/return may counteract the increased cost of generating muscular force at faster speeds and thus allows for the invariance in metabolic cost. This methodologically impressive study sets the stage for further work to investigate the relation of hopping speed to metabolic cost more definitively.

Reviewed by eLife, preLights

Aurora B controls microtubule stability to regulate abscission dynamics in stem cells

1. Snježana Kodba
2. Amber Öztop
3. Eri van Berkum
4. Eugene A. Katrukha
5. Malina K. Iwanski
6. Wilco Nijenhuis
7. Lukas C. Kapitein
8. Agathe Chaigne

Reviewed by preLights

Evolution of tandem repeats in putative CSP to enhance its function: A recent and exclusive event in Plasmodium vivax in India

1. Manoswini Dash
2. Veena Pande
3. Aparup Das
4. Abhinav Sinha

Reviewed by preLights

A tension-induced morphological transition shapes the avian extra-embryonic territory

1. Arthur Michaut
2. Alexander Chamolly
3. Aurélien Villedieu
4. Francis Corson
5. Jérôme Gros

Reviewed by preLights