Evaluated articles

Context specific ubiquitin modification of ribosomes regulates translation under oxidative stress

1. Shannon E. Dougherty
2. Géssica C. Barros
3. Matthew W. Foster
4. Guoshou Teo
5. Hyungwon Choi
6. Gustavo M. Silva

Reviewed by Review Commons

Temporally resolved single cell transcriptomics in a human model of amniogenesis

1. Nikola Sekulovski
2. Amber E Carleton
3. Anusha A Rengarajan
4. Chien-Wei Lin
5. Lauren L Juga
6. Allison E Whorton
7. Jenna Kropp Schmidt
8. Thaddeus Golos
9. Kenichiro Taniguchi

Reviewed by Review Commons

Compensatory evolution to DNA replication stress is robust to nutrient availability

1. Mariana Natalino
2. Marco Fumasoni

Reviewed by Review Commons

A Dual Role for the PP2A Phosphatase in Hippo Signalling Regulation

1. Aashika Sekar
2. Alberto Rizzo
3. Elodie Sins
4. Alexander D. Fulford
5. Paulo S. Ribeiro

Reviewed by Review Commons

Sex‐dimorphic gene regulation in murine macrophages across niches

1. Cassandra J McGill
2. Olivia S White
3. Ryan J Lu
4. Nirmal K Sampathkumar
5. Bérénice A Benayoun

Reviewed by Review Commons

Dendritic atoh1a+ cells serve as Merkel cell precursors during skin development and regeneration

1. Evan W. Craig
2. Erik C. Black
3. Samantha Z. Fernandes
4. Ahlan S. Ferdous
5. Camille E. A. Goo
6. Sheridan M. Sargent
7. Elgene J. A. Quitevis
8. Avery Angell Swearer
9. Nathaniel G. Yee
10. Jimann Shin
11. Lilianna Solnica-Krezel
12. Jeffrey P. Rasmussen

Reviewed by Review Commons

Mitochondrial dysfunction heightens the integrated stress response to drive ALS pathogenesis

1. Curran Landry
2. James Costanzo
3. Miguel Mitne-Neto
4. Mayana Zatz
5. Ashleigh Schaffer
6. Maria Hatzoglou
7. Alysson Muotri
8. Helen Cristina Miranda

Reviewed by Review Commons

Hypoxia impedes differentiation of cranial neural crest cells into derivatives relevant for craniofacial development

1. Theresa Schmid
2. Gabriele Rodrian
3. Elke Bachmann
4. Alexander Kohler
5. Michael Wegner
6. Lina Gölz
7. Matthias Weider

Reviewed by Review Commons

Lipid peroxidation and type I interferon coupling fuels pathogenic macrophage activation causing tuberculosis susceptibility

1. Shivraj M Yabaji
2. Vadim Zhernovkov
3. Prasanna Babu Araveti
4. Suruchi Lata
5. Oleksii S Rukhlenko
6. Salam Al Abdullatif
7. Arthur Vanvalkenburg
8. Yuriy O Alekseyev
9. Qicheng Ma
10. Gargi Dayama
11. Nelson C Lau
12. W Evan Johnson
13. William R Bishai
14. Nicholas A Crossland
15. Joshua D Campbell
16. Boris N Kholodenko
17. Alexander A Gimelbrant
18. Lester Kobzik
19. Igor Kramnik

• Curated by eLife

  eLife Assessment

  Yabaji et al. reports a fundamental study highlighting the mechanistic connection for susceptibility to TB infection via the sst1 locus, this was shown to involve increased IFN and Myc production causing the down-regulation of anti-oxidant defence genes and chronic lipidation. Ultimately, lipid peroxidation may underlie infectivity and macrophage dysfunction. Overall, the data presented are compelling, supported by a well designed multi-omics approach and the findings will be of broad interest to researchers investigating the molecular mechanisms of TB infection.

  [Editors' note: this paper was reviewed by Review Commons.]

Reviewed by eLife, Review Commons

Dual-action peptide shuttles rescue Cu-amyloid-β-induced neurotoxicity and relocate Cu intracellularly

1. Michael Okafor
2. David Schmitt
3. Enrico Falcone
4. Stéphane Gasman
5. Laurent Raibaut
6. Christelle Hureau
7. Peter Faller
8. Nicolas Vitale

Reviewed by Review Commons

A conserved chronobiological complex times C. elegans development

1. Rebecca K. Spangler
2. Kathrin Braun
3. Guinevere E. Ashley
4. Marit van der Does
5. Daniel Wruck
6. Andrea Ramos Coronado
7. James Matthew Ragle
8. Vytautas Iesmantavicius
9. Lucas J. Morales Moya
10. Keya Jonnalagadda
11. Carrie L. Partch
12. Helge Großhans
13. Jordan D. Ward

Reviewed by Review Commons

Plasma Membrane Remodelling in GM2 Gangliosidoses Drives Synaptic Dysfunction

1. Alex S. Nicholson
2. David A. Priestman
3. Robin Antrobus
4. James C. Williamson
5. Reuben Bush
6. Henry G. Barrow
7. Emily Smith
8. Kostantin Dobrenis
9. Nicholas A. Bright
10. Frances M. Platt
11. Janet E. Deane

Reviewed by Review Commons

Dual roles of EGO-1 and RRF-1 in regulating germline exo-RNAi efficiency in Caenorhabditis elegans

1. Katsufumi Dejima
2. Keita Yoshida
3. Shohei Mitani

Reviewed by Review Commons

Selective autophagy fine-tunes Stat92E activity by degrading Su(var)2-10/PIAS during glial injury signaling in Drosophila

1. Virág Vincze
2. Zsombor Esküdt
3. Erzsébet Fehér-Juhász
4. Aishwarya Sanjay Chhatre
5. András Jipa
6. Martin Csordós
7. Anna Rita Galambos
8. Dalma Feil-Börcsök
9. Gábor Juhász
10. Áron Szabó

Reviewed by Review Commons

TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence

1. Jennifer Kahlhofer
2. Nikolas Marchet
3. Brigitta Seifert
4. Kristian Zubak
5. Madlen Hotze
6. Anna-Sophia Egger
7. Claudia Manzl
8. Yannick Weyer
9. Sabine Weys
10. Martin Offterdinger
11. Sebastian Herzog
12. Veronika Reiterer
13. Marcel Kwiatkowski
14. Saskia B. Wortmann
15. Siamak Nemati
16. Johannes A. Mayr
17. Johannes Zschocke
18. Bernhard Radlinger
19. Kathrin Thedieck
20. Lukas A. Huber
21. Hesso Farhan
22. Mariana E.G. de Araujo
23. Susanne Kaser
24. Sabine Scholl-Bürgi
25. Daniela Karall
26. David Teis

Reviewed by Review Commons

Progressive chromosome shape changes quantified during cell divisions

1. Yasutaka Kakui
2. Yoshiharu Kusano
3. Tereza Clarence
4. Maya Lopez
5. Toru Hirota
6. Bhavin S. Khatri
7. Frank Uhlmann

Reviewed by Review Commons

Distinct proliferative and neuronal programmes of chromatin binding and gene activation by ASCL1 are cell cycle stage-specific

1. William F. Beckman
2. Lydia M. Parkinson
3. Lewis Chaytor
4. Anna Philpott

Reviewed by Review Commons

Morphology-dependent entry kinetics and spread of influenza A virus

1. Sarah Peterl
2. Carmen M Lahr
3. Carl N Schneider
4. Janis Meyer
5. Xenia Podlipensky
6. Vera Lechner
7. Maria Villiou
8. Larissa Eis
9. Steffen Klein
10. Charlotta Funaya
11. Elisabetta Ada Cavalcanti-Adam
12. Frederik Graw
13. Christine Selhuber-Unkel
14. Karl Rohr
15. Petr Chlanda

Reviewed by Review Commons, PREreview

One probe fits all: a highly customizable modular RNA in situ hybridization platform expanding the application of SABER DNA probes

1. Kirill Ustyantsev
2. Mattia Stranges
3. Filippo Giovanni Volpe
4. Stijn Mouton
5. Eugene Berezikov

Reviewed by Review Commons

SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion

1. Jianchao Zhang
2. Andrew Kennedy
3. Daniel Macedo de Melo Jorge
4. Lijuan Xing
5. Whitney Reid
6. Sarah Bui
7. Joseph Joppich
8. Molly Rose
9. Sevval Ercan
10. Qiyi Tang
11. David Ginsburg
12. Andrew W. Tai
13. Yanzhuang Wang

Reviewed by Review Commons, ScreenIT