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  1. Ripply1 and Gsc collectively suppress anterior endoderm differentiation from prechordal plate progenitors

    This article has 18 authors:
    1. Tao Cheng
    2. Xiang Liu
    3. Yang Dong
    4. Yi-Meng Tian
    5. Yan-Yi Xing
    6. Chen-Yi Chen
    7. Cong Liu
    8. Yun-Fei Li
    9. Ying Huang
    10. Ding-Hao Zhuo
    11. Xiao Xu
    12. Jing-Yun Luan
    13. Xin-Xin Fu
    14. Zi-Xin Jin
    15. Jing Mo
    16. Xiang Xu
    17. Hong-Qing Liang
    18. Peng-Fei Xu
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This study provides a useful analysis of the changes in chromatin organization and gene expression that occur during the differentiation of two cell types (anterior endoderm and prechordal plate) from a common progenitor in zebrafish. Although the findings are consistent with previous work, the evidence presented in the study appears to be incomplete and would benefit from more rigorous interpretation of single-cell data, more in-depth lineage tracing, overexpression experiments with physiological levels of Ripply, and a clearer justification for using an explant system. With these modifications, this paper will be of interest to zebrafish developmental biologists investigating mechanisms underlying differentiation.

    Reviewed by eLife, Review Commons

    This article has 8 evaluationsAppears in 2 listsLatest version Latest activity
  2. Single-cell profiling and zebrafish avatars reveal LGALS1 as immunomodulating target in glioblastoma

    This article has 22 authors:
    1. Lise Finotto
    2. Basiel Cole
    3. Wolfgang Giese
    4. Elisabeth Baumann
    5. Annelies Claeys
    6. Maxime Vanmechelen
    7. Brecht Decraene
    8. Marleen Derweduwe
    9. Nikolina Dubroja Lakic
    10. Gautam Shankar
    11. Madhu Nagathihalli Kantharaju
    12. Jan Philipp Albrecht
    13. Ilse Geudens
    14. Fabio Stanchi
    15. Keith L. Ligon
    16. Bram Boeckx
    17. Diether Lambrechts
    18. Kyle Harrington
    19. Ludo Van Den Bosch
    20. Steven De Vleeschouwer
    21. Frederik De Smet
    22. Holger Gerhardt

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity
  3. The obesity-linked human lncRNA AATBC regulates adipocyte plasticity by stimulating mitochondrial dynamics and respiration

    This article has 24 authors:
    1. Maude Giroud
    2. Stefan Kotschi
    3. Yun Kwon
    4. Ophélia Le Thuc
    5. Anne Hoffmann
    6. Manuel Gil-Lozano
    7. Michael Karbiener
    8. Juan Carlos Higareda-Almaraz
    9. Sajjad Khani
    10. Daniel Tews
    11. Pamela Fischer-Posovszky
    12. Wenfei Sun
    13. Hua Dong
    14. Adhideb Ghosh
    15. Christian Wolfrum
    16. Martin Wabitsch
    17. Kirsi A. Virtanen
    18. Matthias Blüher
    19. Søren Nielsen
    20. Anja Zeigerer
    21. Cristina García-Cáceres
    22. Marcel Scheideler
    23. Stephan Herzig
    24. Alexander Bartelt

    Reviewed by Review Commons

    This article has 4 evaluationsAppears in 1 listLatest version Latest activity