Evaluated articles

A Standard-Based Citywide Health Information Exchange for Public Health in Response to COVID-19: Development Study

1. Bala Hota
2. Paul Casey
3. Anne F McIntyre
4. Jawad Khan
5. Shafiq Rab
6. Aneesh Chopra
7. Omar Lateef
8. Jennifer E Layden

Reviewed by ScreenIT

Safety-Critical Control of Active Interventions for COVID-19 Mitigation

1. Aaron D. Ames
2. Tamás G. Molnár
3. Andrew W. Singletary
4. Gábor Orosz

Reviewed by ScreenIT

Modelling the potential spread of virus during soccer matches

1. Nikolas Sten Knudsen
2. Manuel Mounir Demetry Thomasen
3. Thomas Bull Andersen

Reviewed by ScreenIT

Diagnosis of COVID-19 from X-rays Using Combined CNN-RNN Architecture with Transfer Learning

1. Mabrook S. Al-Rakhami
2. Md. Milon Islam
3. Md. Zabirul Islam
4. Amanullah Asraf
5. Ali Hassan Sodhro
6. Weiping Ding

Reviewed by ScreenIT

Inheritance of a common androgen synthesis variant allele is associated with female COVID susceptibility in UK Biobank

1. Jeffrey M McManus
2. Navin Sabharwal
3. Peter Bazeley
4. Nima Sharifi

Reviewed by ScreenIT

Transmission of SARS-CoV-2 before and after symptom onset: impact of nonpharmaceutical interventions in China

1. Mary Bushman
2. Colin Worby
3. Hsiao-Han Chang
4. Moritz U. G. Kraemer
5. William P. Hanage

Reviewed by ScreenIT

Inhibition of SARS-CoV-2 polymerase by nucleotide analogs: a single molecule perspective

1. Mona Seifert
2. Subhas Chandra Bera
3. Pauline van Nies
4. Robert N. Kirchdoerfer
5. Ashleigh Shannon
6. Thi-Tuyet-Nhung Le
7. Xiangzhi Meng
8. Hongjie Xia
9. James M. Wood
10. Lawrence D. Harris
11. Flávia S. Papini
12. Jamie J. Arnold
13. Steven C. Almo
14. Tyler L. Grove
15. Pei-Yong Shi
16. Yan Xiang
17. Bruno Canard
18. Martin Depken
19. Craig E. Cameron
20. David Dulin

• Curated by eLife

  Evaluation Summary:

  This work presented in this manuscript paper may advance our understanding of an important class of anti-viral drugs (nucleoside analogs) that target polymerase enzymes by being directly incorporated into the product strand. This class of drugs is known to be quite diverse in their precise mechanisms of action, yet many of the particular details have remained elusive, often due to experimental limitations. The current study employs a single-molecule magnetic-tweezers platform to provide a new paradigm for the mechanism of drug remdesivir against the SARS-CoV-2 polymerase target. The authors propose that remdesivir does not prevent the complete viral RNA synthesis but causes an increase of polymerase pausing and back tracking. This paper is of broad interest to readers and scientists working on SARS-CoV-2 and general nucleotide inhibitors. The work includes the single molecule characterization of other NAs.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife, ScreenIT

Estimating the Cumulative Incidence of SARS-CoV-2 Infection and the Infection Fatality Ratio in Light of Waning Antibodies

1. Kayoko Shioda
2. Max S.Y. Lau
3. Alicia N.M. Kraay
4. Kristin N. Nelson
5. Aaron J. Siegler
6. Patrick S. Sullivan
7. Matthew H. Collins
8. Joshua S. Weitz
9. Benjamin A. Lopman

Reviewed by ScreenIT

High infectiousness immediately before COVID-19 symptom onset highlights the importance of continued contact tracing

1. William S Hart
2. Philip K Maini
3. Robin N Thompson

• Curated by eLife

  Evaluation Summary:

  The manuscript uses a new approach to model the infectiousness profile of COVID-19 infected individuals. The work suggests a higher proportion of pre-symptomatic infectiousness in COVID-19 than the current evidence. The findings are of great interest to public health policy makers. The methodology is of general interest to modellers working on COVID-19.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 and Reviewer #3 agreed to share their names with the authors.)

Reviewed by eLife, ScreenIT

The Potential Role of an Aberrant Mucosal Immune Response to SARS-CoV-2 in the Pathogenesis of IgA Nephropathy

1. Zhao Zhang
2. Guorong Zhang
3. Meng Guo
4. Wanyin Tao
5. Xingzi Liu
6. Haiming Wei
7. Tengchuan Jin
8. Yuemiao Zhang
9. Shu Zhu

Reviewed by ScreenIT

Tracking the mental health of home-carers during the first COVID-19 national lockdown: evidence from a nationally representative UK survey

1. Elise Whitley
2. Kelly Reeve
3. Michaela Benzeval

Reviewed by ScreenIT

Bacterial superinfection pneumonia in SARS-CoV-2 respiratory failure

1. Chiagozie O. Pickens
2. Catherine A. Gao
3. Michael Cuttica
4. Sean B. Smith
5. Lorenzo Pesce
6. Rogan Grant
7. Mengjia Kang
8. Luisa Morales-Nebreda
9. Avni A. Bavishi
10. Jason Arnold
11. Anna Pawlowski
12. Chao Qi
13. GR Scott Budinger
14. Benjamin D. Singer
15. Richard G. Wunderink
16. for the NU COVID Investigators

Reviewed by ScreenIT

COVID-19: Spatial analysis of hospital case-fatality rate in France

1. Marc Souris
2. Jean-Paul Gonzalez

Reviewed by ScreenIT

Incidence and Case-Fatality Ratio of COVID-19 infection in relation to Tobacco Smoking, Population Density and Age Demographics in the USA: could Particulate Matter derived from Tobacco Smoking act as a Vector for COVID-19 transmission?

1. Yves Muscat Baron

Reviewed by ScreenIT

COVID ‐19 pandemic‐related lockdown: response time is more important than its strictness

1. Gil Loewenthal
2. Shiran Abadi
3. Oren Avram
4. Keren Halabi
5. Noa Ecker
6. Natan Nagar
7. Itay Mayrose
8. Tal Pupko

Reviewed by ScreenIT

A statistical forecast of LOW mortality and morbidity due to COVID-19, in ARGENTINA and other Southern Hemisphere countries

1. Cesar A. Barbero

Reviewed by ScreenIT

Preliminary optimisation of a simplified sample preparation method to permit direct detection of SARS-CoV-2 within saliva samples using reverse-transcription loop-mediated isothermal amplification (RT-LAMP)

1. Emma L.A. Howson
2. Stephen P. Kidd
3. Bryony Armson
4. Alice Goring
5. Jason Sawyer
6. Claire Cassar
7. David Cross
8. Tom Lewis
9. Jess Hockey
10. Samantha Rivers
11. Saira Cawthraw
12. Ashley Banyard
13. Paul Anderson
14. Sabah Rahou
15. Michael Andreou
16. Nick Morant
17. Duncan Clark
18. Charlotte Walsh
19. Shailen Laxman
20. Rebecca Houghton
21. Joanne Slater-Jefferies
22. Paula Costello
23. Ian Brown
24. Nicholas Cortes
25. Keith M. Godfrey
26. Veronica L. Fowler

Reviewed by ScreenIT

Vitamin D – contrary to vitamin K – does not associate with clinical outcome in hospitalized COVID-19 patients

1. Jona Walk
2. Anton S.M. Dofferhoff
3. Jody M.W. van den Ouweland
4. Henny van Daal
5. Rob Janssen

Reviewed by ScreenIT

Returning to a Normal Life via COVID-19 Vaccines in the United States: A Large-scale Agent-Based Simulation Study

1. Junjiang Li
2. Philippe Giabbanelli

Reviewed by ScreenIT

Using newspaper obituaries to “nowcast” daily mortality: Evidence from the Italian COVID-19 hot-spots

1. Paolo Buonanno
2. Marcello Puca

Reviewed by ScreenIT