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  1. Omicron BA.1 and BA.2 are antigenically distinct SARS-CoV-2 variants

    This article has 21 authors:
    1. Anna Z. Mykytyn
    2. Melanie Rissmann
    3. Adinda Kok
    4. Miruna E. Rosu
    5. Debby Schipper
    6. Tim I. Breugem
    7. Petra B. van den Doel
    8. Felicity Chandler
    9. Theo Bestebroer
    10. Maurice de Wit
    11. Martin E. van Royen
    12. Richard Molenkamp
    13. Bas B. Oude Munnink
    14. Rory D. de Vries
    15. Corine GeurtsvanKessel
    16. Derek J. Smith
    17. Marion P. G. Koopmans
    18. Barry Rockx
    19. Mart M. Lamers
    20. Ron Fouchier
    21. Bart L. Haagmans

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  2. A high-throughput yeast display approach to profile pathogen proteomes for MHC-II binding

    This article has 4 authors:
    1. Brooke D Huisman
    2. Zheng Dai
    3. David K Gifford
    4. Michael E Birnbaum
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      The manuscript builds on previous work to design yeast display libraries representing full viral proteomes with overlapping 15-mer peptides binding to specific HLA-DR alleles, and therefore potentially immunogenic for CD4 T cell responses. The authors use SARS-CoV-2 and dengue viruses as proof of concept and identify a number of potentially immunogenic peptides not predicted by current algorithms. The methods are interesting and promising and will be of interest to a wide range of researchers in immunological and infectious disease studies.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their name with the authors.)

    Reviewed by eLife, ScreenIT

    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  3. Long-term Durable Humoral Immune Response to Heterologous Antigenic Exposure Post six months by Natural SARS-CoV-2 Infection and Vaccination

    This article has 27 authors:
    1. Gaurav Batra
    2. Deepika Rathna Murugesan
    3. Souvick Chattopadhyay
    4. Farha Mehdi
    5. Ayushi
    6. Mudita Gosain
    7. Savita Singh
    8. Soon Jyoti Das
    9. Suprit Deshpande
    10. Jayanta Bhattacharya
    11. Anil K Pandey
    12. Sankalp Jha
    13. Shweta Goswami
    14. Asim Das
    15. Tanima Dwivedi
    16. Nandini Sharma
    17. Suresh Kumar
    18. Pragya Sharma
    19. Seema Kapoor
    20. Pallavi Kshetrapal
    21. Nitya Wadhwa
    22. Ramachandran Thiruvengadam
    23. Rakesh Kumar
    24. Ritu Gupta
    25. Pramod Kumar Garg
    26. Shinjini Bhatnagar
    27. DBT Consortium for COVID-19 Research

    Reviewed by ScreenIT

    This article has 1 evaluationAppears in 1 listLatest version Latest activity