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  1. Reduced antibody cross-reactivity following infection with B.1.1.7 than with parental SARS-CoV-2 strains

    This article has 29 authors:
    1. Nikhil Faulkner
    2. Kevin W Ng
    3. Mary Y Wu
    4. Ruth Harvey
    5. Marios Margaritis
    6. Stavroula Paraskevopoulou
    7. Catherine Houlihan
    8. Saira Hussain
    9. Maria Greco
    10. William Bolland
    11. Scott Warchal
    12. Judith Heaney
    13. Hannah Rickman
    14. Moria Spyer
    15. Daniel Frampton
    16. Matthew Byott
    17. Tulio de Oliveira
    18. Alex Sigal
    19. Svend Kjaer
    20. Charles Swanton
    21. Sonia Gandhi
    22. Rupert Beale
    23. Steve J Gamblin
    24. John W McCauley
    25. Rodney Stuart Daniels
    26. Michael Howell
    27. David Bauer
    28. Eleni Nastouli
    29. George Kassiotis
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      This study describes reduced antibody cross-reactivity between the SARS-CoV-2 B.1.1.7 variant and the parental strain or the B.1.351 variant. Asymmetric antibody responses and reduced neutralizing antibodies against heterogeneous variants have been demonstrated in multiple studies. The current study reports reduction of B.1.1.7 COVID-19 sera against the SARS-CoV-2 parental strain and B.1.351. This observation is interesting and could be useful for future vaccine development. The work is of interest to virologists and infectious disease specialists.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

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    This article has 5 evaluationsAppears in 2 listsLatest version Latest activity
  2. Calcitriol, the active form of vitamin D, is a promising candidate for COVID-19 prophylaxis

    This article has 20 authors:
    1. Chee Keng Mok
    2. Yan Ling Ng
    3. Bintou Ahmadou Ahidjo
    4. Regina Ching Hua Lee
    5. Marcus Wing Choy Loe
    6. Jing Liu
    7. Kai Sen Tan
    8. Parveen Kaur
    9. Wee Joo Chng
    10. John Eu-Li Wong
    11. De Yun Wang
    12. Erwei Hao
    13. Xiaotao Hou
    14. Yong Wah Tan
    15. Tze Minn Mak
    16. Cui Lin
    17. Raymond Lin
    18. Paul Tambyah
    19. JiaGang Deng
    20. Justin Jang Hann Chu

    Reviewed by ScreenIT

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  3. Coincident rapid expansion of two SARS-CoV-2 lineages with enhanced infectivity in Nigeria

    This article has 16 authors:
    1. Egon A. Ozer
    2. Lacy M. Simons
    3. Olubusuyi M. Adewumi
    4. Adeola A. Fowotade
    5. Ewean C. Omoruyi
    6. Johnson A. Adeniji
    7. Taylor J. Dean
    8. Janet Zayas
    9. Pavan P. Bhimalli
    10. Michelle K. Ash
    11. Adam Godzik
    12. Jeffrey R. Schneider
    13. JoĂŁo I. Mamede
    14. Babafemi O. Taiwo
    15. Judd F. Hultquist
    16. Ramon Lorenzo-Redondo

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    This article has 1 evaluationAppears in 1 listLatest version Latest activity
  4. Systemic and mucosal antibody responses specific to SARS-CoV-2 during mild versus severe COVID-19

    This article has 25 authors:
    1. Carlo Cervia
    2. Jakob Nilsson
    3. Yves Zurbuchen
    4. Alan Valaperti
    5. Jens Schreiner
    6. Aline Wolfensberger
    7. Miro E. Raeber
    8. Sarah Adamo
    9. Sebastian Weigang
    10. Marc Emmenegger
    11. Sara Hasler
    12. Philipp P. Bosshard
    13. Elena De Cecco
    14. Esther Bächli
    15. Alain Rudiger
    16. Melina StĂĽssi-Helbling
    17. Lars C. Huber
    18. Annelies S. Zinkernagel
    19. Dominik J. Schaer
    20. Adriano Aguzzi
    21. Georg Kochs
    22. Ulrike Held
    23. Elsbeth Probst-MĂĽller
    24. Silvana K. Rampini
    25. Onur Boyman

    Reviewed by ScreenIT

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity