Evaluated articles

Direct cell extraction of membrane proteins for structure–function analysis

1. Ieva Drulyte
2. Aspen Rene Gutgsell
3. Pilar Lloris-Garcerá
4. Michael Liss
5. Stefan Geschwindner
6. Mazdak Radjainia
7. Jens Frauenfeld
8. Robin Löving

Reviewed by ASAPbio crowd review

Profiling dynamic RNA–protein interactions using small-molecule-induced RNA editing

1. Kyung W. Seo
2. Ralph E. Kleiner

Reviewed by ASAPbio crowd review

ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt

1. Alexandria L Shaw
2. Matthew AH Parson
3. Linda Truebestein
4. Meredith L Jenkins
5. Thomas A Leonard
6. John E Burke

Reviewed by ASAPbio crowd review

MitoStores: chaperone‐controlled protein granules store mitochondrial precursors in the cytosol

1. Lena Krämer
2. Niko Dalheimer
3. Markus Räschle
4. Zuzana Storchová
5. Jan Pielage
6. Felix Boos
7. Johannes M Herrmann

Reviewed by ASAPbio crowd review

Adiponectin reverses β‐Cell damage and impaired insulin secretion induced by obesity

1. Ana Cláudia Munhoz
2. Julian D. C. Serna
3. Eloisa Aparecida Vilas‐Boas
4. Camille C. Caldeira da Silva
5. Tiago G. Santos
6. Francielle C. Mosele
7. Sergio L. Felisbino
8. Vilma Regina Martins
9. Alicia J. Kowaltowski

Reviewed by ASAPbio crowd review

MND1 enables repair of two-ended DNA double-strand breaks

1. Lisa Koob
2. Anoek Friskes
3. Louise van Bergen
4. Femke M. Feringa
5. Bram van den Broek
6. Emma S. Koeleman
7. Michael Schubert
8. Vincent A. Blomen
9. Thijn R. Brummelkamp
10. Lenno Krenning
11. René H. Medema

Reviewed by ASAPbio crowd review

Golgi localized Arl15 regulates cargo transport, cell adhesion and motility

1. Prerna Sharma
2. Pooja Hoovina Venkatesh
3. Neha Paddillaya
4. Nikita Shah
5. BR Rajeshwari
6. Archishman Dakua
7. Aravind Penmatsa
8. Nagaraj Balasubramanian
9. Namrata Gundiah
10. Subba Rao Gangi Setty

Reviewed by ASAPbio crowd review

Anti-apoptotic BH3-only proteins inhibit Bak-dependent apoptosis

1. Sebastian Ruehl
2. Clifford S. Guy
3. Zhenrui Li
4. Mao Yang
5. Tudor Moldoveanu
6. Douglas R. Green

Reviewed by ASAPbio crowd review

Comparative analysis of actin visualization by genetically encoded probes in cultured neurons

1. Attila Ignácz
2. Domonkos Nagy-Herczeg
3. Angelika Hausser
4. Katalin Schlett

Reviewed by ASAPbio crowd review

Depletion of Plasma Membrane PI4P by ORP5 Requires Hydrolysis by SAC1 in Acceptor Membranes

1. Colleen P. Doyle
2. Liz Timple
3. Gerald R. V. Hammond

Reviewed by ASAPbio crowd review

Dynamic in vivo mapping of the methylproteome using a chemoenzymatic approach

1. Jonathan Farhi
2. Robert B. Jones
3. Richard S. Lee
4. Ashish K. Verma
5. Kiran K. Parwani
6. Kuei-Chien Tang
7. Benjamin Emenike
8. Pritha Bagchi
9. Monika Raj
10. Jennifer M. Spangle

Reviewed by ASAPbio crowd review

PERK-ATAD3A interaction protects mitochondrial proteins synthesis during ER stress

1. Daniel T. Hughes
2. Karinder K. Brar
3. Jordan L. Morris
4. Kelly Subramanian
5. Shivaani Krishna
6. Fei Gao
7. Lara-Sophie Rieder
8. Joshua Freeman
9. Heather L. Smith
10. Rebekkah Jukes-Jones
11. Jodi Nunnari
12. Julien Prudent
13. Adrian J. Butcher
14. Giovanna R. Mallucci

Reviewed by ASAPbio crowd review

Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control

1. Franziska Nadler
2. Elena Lavdovskaia
3. Angelique Krempler
4. Luis Daniel Cruz-Zaragoza
5. Sven Dennerlein
6. Ricarda Richter-Dennerlein

Reviewed by ASAPbio crowd review

Short-term molecular consequences of chromosome mis-segregation for genome stability

1. Lorenza Garribba
2. Giuseppina De Feudis
3. Valentino Martis
4. Martina Galli
5. Marie Dumont
6. Yonatan Eliezer
7. René Wardenaar
8. Marica Rosaria Ippolito
9. Divya Ramalingam Iyer
10. Andréa E. Tijhuis
11. Diana C. J. Spierings
12. Michael Schubert
13. Silvia Taglietti
14. Chiara Soriani
15. Simon Gemble
16. Renata Basto
17. Nick Rhind
18. Floris Foijer
19. Uri Ben-David
20. Daniele Fachinetti
21. Ylli Doksani
22. Stefano Santaguida

Reviewed by ASAPbio crowd review

lncRNA H19/Let7b/EZH2 axis regulates somatic cell senescence

1. Manali Potnis
2. Justin Do
3. Olivia El Naggar
4. Eishi Noguchi
5. Christian Sell

• Curated by eLife

  eLife Assessment

  In this manuscript, Sell et al., investigate the role of the long non-coding RNA H19 in regulating cellular senescence. Using several cell models they identify upstream and downstream effectors of H19 including let-7 and EZH2. The advances in this work include the identification of a specific cascade of factors connecting H19, senescence and the actions of rapamycin.

Reviewed by eLife, ASAPbio crowd review

Nanog organizes transcription bodies

1. Ksenia Kuznetsova
2. Noémie M. Chabot
3. Martino Ugolini
4. Edlyn Wu
5. Manan Lalit
6. Haruka Oda
7. Yuko Sato
8. Hiroshi Kimura
9. Florian Jug
10. Nadine L. Vastenhouw

Reviewed by ASAPbio crowd review

Structural basis for RNA-mediated assembly of type V CRISPR-associated transposons

1. Michael Schmitz
2. Irma Querques
3. Seraina Oberli
4. Christelle Chanez
5. Martin Jinek

Reviewed by ASAPbio crowd review

Replicative aging impedes stress-induced assembly of a key human protein disaggregase

1. Yasith Mathangasinghe
2. Niels Alberts
3. Carlos J. Rosado
4. Dezerae Cox
5. Natalie L. Payne
6. Angelique R. Ormsby
7. Keziban Merve Alp
8. Roman Sakson
9. Sanjeev Uthishtran
10. Thomas Ruppert
11. Senthil Arumugam
12. Danny M. Hatters
13. Harm H. Kampinga
14. Nadinath B. Nillegoda

Reviewed by ASAPbio crowd review

A Single-Component Luminescent Biosensor for the SARS-CoV-2 Spike Protein

1. Matthew Ravalin
2. Heegwang Roh
3. Rahul Suryawanshi
4. G. Renuka Kumar
5. John E. Pak
6. Melanie Ott
7. Alice Y. Ting

Reviewed by ASAPbio crowd review

Single-cell intracellular pH dynamics regulate the cell cycle by timing the G1 exit and G2 transition

1. Julia S. Spear
2. Katharine A. White

Reviewed by Arcadia Science, ASAPbio crowd review