@maria_eichel's saved articles

Unmyelinated neurons use Neuregulin signals to promote myelination of neighboring neurons in the CNS

1. Daniel E. Lysko
2. William S. Talbot

Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease

1. Erik Schäffner
2. Mar Bosch-Queralt
3. Julia M. Edgar
4. Maria Lehning
5. Judith Strauß
6. Niko Fleischer
7. Theresa Kungl
8. Peter Wieghofer
9. Stefan A. Berghoff
10. Tilo Reinert
11. Martin Krueger
12. Markus Morawski
13. Wiebke Möbius
14. Alonso Barrantes-Freer
15. Jens Stieler
16. Ting Sun
17. Gesine Saher
18. Markus H. Schwab
19. Christoph Wrede
20. Maximilian Frosch
21. Marco Prinz
22. Daniel S. Reich
23. Alexander Flügel
24. Christine Stadelmann
25. Robert Fledrich
26. Klaus-Armin Nave
27. Ruth M. Stassart

Oligodendrocyte origin and development in the zebrafish visual system

1. Adrián Santos‐Ledo
2. Cristina Pérez‐Montes
3. Laura DeOliveira‐Mello
4. Rosario Arévalo
5. Almudena Velasco

Oligodendrocytes form paranodal bridges that generate chains of myelin sheaths that are vulnerable to degeneration with age

1. Cody L. Call
2. Sarah A. Neely
3. Jason J. Early
4. Owen G. James
5. Lida Zoupi
6. Anna C. Williams
7. Siddharthan Chandran
8. David A. Lyons
9. Dwight E. Bergles

Single-nuclei paired multiomic analysis of young, aged, and Parkinson’s disease human midbrain reveals age- and disease-associated glial changes and their contribution to Parkinson’s disease

1. Levi Adams
2. Min Kyung Song
3. Yoshiaki Tanaka
4. Yoon-Seong Kim

Chronic demyelination of rabbit lesions is attributable to failed oligodendrocyte progenitor cell repopulation

1. James J. M. Cooper
2. Jessie J. Polanco
3. Darpan Saraswat
4. Jennifer J. Peirick
5. Anna Seidl
6. Yi Li
7. Dan Ma
8. Fraser J. Sim

FRaeppli, a multispectral imaging toolbox for cell tracing and dense tissue analysis in zebrafish

1. Sara Caviglia
2. Iris A. Unterweger
3. Akvilė Gasiūnaitė
4. Alexandre E. Vanoosthuyse
5. Francesco Cutrale
6. Le A. Trinh
7. Scott E. Fraser
8. Stephan C. F. Neuhauss
9. Elke A. Ober

Cd59 and inflammation regulate Schwann cell development

1. Ashtyn T Wiltbank
2. Emma R Steinson
3. Stacey J Criswell
4. Melanie Piller
5. Sarah Kucenas

• Curated by eLife

  Evaluation Summary:

  This paper by Wiltbank et al. "Cd59 and inflammation orchestrate Schwann cell development" investigates the function of the small GPI-anchored protein Cd59, a protein known to suppress complement mediated inflammation, in Schwann cell development and myelination, using zebrafish as a model system. This paper will be of broad interest to developmental biologists, glial biologists and immunologists, as it suggests the interesting and novel findings that Cd59 regulates Schwann cell development, mainly by modulating Schwann cell proliferation.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

Reviewed by eLife

Axonal Length Determines Distinct Homeostatic Phenotypes in Human iPSC Derived Motor Neurons on a Bioengineered Platform

1. Cathleen Hagemann
2. Carmen Moreno Gonzalez
3. Ludovica Guetta
4. Giulia Tyzack
5. Ciro Chiappini
6. Andrea Legati
7. Rickie Patani
8. Andrea Serio

Axon Diameter Measurements using Diffusion MRI are Infeasible

1. Michael Paquette
2. Cornelius Eichner
3. Thomas R. Knösche
4. Alfred Anwander

Myelination Deficits in the Auditory Brainstem of a Mouse Model of Fragile X Syndrome

1. Alexandra Lucas
2. Shani Poleg
3. Achim Klug
4. Elizabeth A. McCullagh

mTORC2 Loss in Oligodendrocyte Progenitor Cells Results in Regional Hypomyelination in the Central Nervous System

1. Kristin D. Dahl
2. Adam R. Almeida
3. Hannah A. Hathaway
4. Jennifer Bourne
5. Tanya L. Brown
6. Lisbet T. Finseth
7. Teresa L. Wood
8. Wendy B. Macklin

Mild respiratory SARS-CoV-2 infection can cause multi-lineage cellular dysregulation and myelin loss in the brain

1. Anthony Fernández-Castañeda
2. Peiwen Lu
3. Anna C. Geraghty
4. Eric Song
5. Myoung-Hwa Lee
6. Jamie Wood
7. Belgin Yalçın
8. Kathryn R. Taylor
9. Selena Dutton
10. Lehi Acosta-Alvarez
11. Lijun Ni
12. Daniel Contreras-Esquivel
13. Jeff R. Gehlhausen
14. Jon Klein
15. Carolina Lucas
16. Tianyang Mao
17. Julio Silva
18. Mario A. Peña-Hernández
19. Alexandra Tabachnikova
20. Takehiro Takahashi
21. Laura Tabacof
22. Jenna Tosto-Mancuso
23. Erica Breyman
24. Amy Kontorovich
25. Dayna McCarthy
26. Martha Quezado
27. Marco Hefti
28. Daniel Perl
29. Rebecca Folkerth
30. David Putrino
31. Avi Nath
32. Akiko Iwasaki
33. Michelle Monje

Reviewed by ScreenIT

Failed remyelination of the non-human primate optic nerve leads to axon degeneration, retinal damages and visual dysfunction

1. Nadège Sarrazin
2. Estelle Chavret-Reculon
3. Corinne Bachelin
4. Mehdi Felfli
5. Rafik Arab
6. Sophie Gilardeau
7. Elena Brazhnikova
8. Elisabeth Dubus
9. Lydia Yaha-Cherif
10. Jean Lorenceau
11. Serge Picaud
12. Serge Rosolen
13. Pierre Moissonnier
14. Pierre Pouget
15. Anne Baron-Van Evercooren

Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice

1. Vasiliki-Ilya Gargareta
2. Josefine Reuschenbach
3. Sophie B Siems
4. Ting Sun
5. Lars Piepkorn
6. Carolina Mangana
7. Erik Späte
8. Sandra Goebbels
9. Inge Huitinga
10. Wiebke Möbius
11. Klaus-Armin Nave
12. Olaf Jahn
13. Hauke B Werner

• Curated by eLife

  Evaluation Summary:

  In this impressive manuscript the authors study the similarities and differences between the molecules that comprise the insulation that surrounds human brain nerve fibers (myelin), providing essential insight into how to interpret studies of myelin, from the perspective of different species. In all, this manuscript provides a new resource that will be of interest to the myelin community as well as investigators examining the contributions of oligodendrocytes to human neurodegenerative disease.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their names with the authors.)

Reviewed by eLife

A retroviral link to vertebrate myelination through retrotransposon-RNA-mediated control of myelin gene expression

1. Tanay Ghosh
2. Rafael G. Almeida
3. Chao Zhao
4. Abdelkrim Mannioui
5. Elodie Martin
6. Alex Fleet
7. Civia Z. Chen
8. Peggy Assinck
9. Sophie Ellams
10. Ginez A. Gonzalez
11. Stephen C. Graham
12. David H. Rowitch
13. Katherine Stott
14. Ian Adams
15. Bernard Zalc
16. Nick Goldman
17. David A. Lyons
18. Robin J.M. Franklin

Ageing-associated myelin dysfunction drives amyloid deposition in mouse models of Alzheimer’s disease

1. Constanze Depp
2. Ting Sun
3. Andrew Octavian Sasmita
4. Lena Spieth
5. Stefan A. Berghoff
6. Agnes A. Steixner-Kumar
7. Swati Subramanian
8. Wiebke Möbius
9. Sandra Göbbels
10. Gesine Saher
11. Silvia Zampar
12. Oliver Wirths
13. Maik Thalmann
14. Takashi Saito
15. Takaomi Saido
16. Dilja Krueger-Burg
17. Riki Kawaguchi
18. Michael Willem
19. Christian Haass
20. Daniel Geschwind
21. Hannelore Ehrenreich
22. Ruth Stassart
23. Klaus-Armin Nave

Reviewed by preLights

Gli1 Regulates the Postnatal Acquisition of Peripheral Nerve Architecture

1. Brendan Zotter
2. Or Dagan
3. Jacob Brady
4. Hasna Baloui
5. Jayshree Samanta
6. James L. Salzer

Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia

1. Laura Fontenas
2. Sarah Kucenas

Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination

1. Gustavo Della-Flora Nunes
2. Emma R Wilson
3. Edward Hurley
4. Bin He
5. Bert W O'Malley
6. Yannick Poitelon
7. Lawrence Wrabetz
8. M Laura Feltri

• Curated by eLife

  Evaluation Summary:

  This manuscript builds upon the recent observation that Schwann cell (SC)-specific loss of the mitochondrial protein Prohibitin-1 results in a rapid, progressive demyelinating peripheral neuropathy in mice associated with mitochondrial dysfunction. They establish pathways as downstream effectors of mitochondrial dysfunction in Schwann cells. The authors provide a comprehensive evaluation of these pathways following the loss of Prophibitin-1 and identify JUN and mTORC1 as potential mediators of myelin disruption.

  (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #2 agreed to share their name with the authors.)

Reviewed by eLife