Showing page 48 of 48 pages of list content

  1. Extracellular Vimentin as a Target Against SARS‐CoV‐2 Host Cell Invasion

    This article has 14 authors:
    1. Ɓukasz Suprewicz
    2. Maxx Swoger
    3. Sarthak Gupta
    4. Ewelina Piktel
    5. Fitzroy J. Byfield
    6. Daniel V. Iwamoto
    7. Danielle Germann
    8. Joanna Reszeć
    9. Natalia MarciƄczyk
    10. Robert J. Carroll
    11. Paul A. Janmey
    12. J. M. Schwarz
    13. Robert Bucki
    14. Alison E. Patteson

    Reviewed by Rapid Reviews Infectious Diseases, PREreview, ScreenIT

    This article has 4 evaluationsAppears in 3 listsLatest version Latest activity
  2. HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells

    This article has 10 authors:
    1. Thorsten G MĂŒller
    2. Vojtech Zila
    3. Kyra Peters
    4. Sandra Schifferdecker
    5. Mia Stanic
    6. Bojana Lucic
    7. Vibor Laketa
    8. Marina Lusic
    9. Barbara MĂŒller
    10. Hans-Georg KrÀusslich
    This article has been curated by 1 group:
    • Curated by eLife

      Evaluation Summary:

      The authors use a variety of complementary approaches to visualize and characterize events in the first half of the HIV life cycle, with some overlap between the latter studies and the recent (and cited) Zila et al. bioRxiv paper from some of the same authors. The data are generally of high quality, and many findings are in line with recent field advances indicating that reverse transcription completes in the nucleus, that intact/nearly intact cores are imported into the nucleus, and that nuclear uncoating likely occurs immediately prior to integration. The results provide the best evidence to date that intact capsids can enter the nucleus of target cells during infection, and will generally be of interest to the field, although the impact is diminished somewhat by similar recent publications from a number of other groups (including one case that used nearly identical labeling methods to follow viral complexes during infection). Issues that should be addressed include missing controls in some cases, some examples of over-interpretation and uneven citation, and the need for additional images to help bolster some of the claims. Strengths of the study include the rigorous characterization of infection using sophisticated imaging methods and, most importantly, the use of CLEM-ET to visualize viral capsids in the nucleus.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #3 agreed to share their name with the authors.)

    Reviewed by eLife, PREreview

    This article has 5 evaluationsAppears in 3 listsLatest version Latest activity
  3. Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

    This article has 38 authors:
    1. Paloma Cejas
    2. Yingtian Xie
    3. Alba Font-Tello
    4. Klothilda Lim
    5. Sudeepa Syamala
    6. Xintao Qiu
    7. Alok K. Tewari
    8. Neel Shah
    9. Holly M. Nguyen
    10. Radhika A. Patel
    11. Lisha Brown
    12. Ilsa Coleman
    13. Wenzel M. Hackeng
    14. Lodewijk Brosens
    15. Koen M. A. Dreijerink
    16. Leigh Ellis
    17. Sarah Abou Alaiwi
    18. Ji-Heui Seo
    19. Sylvan Baca
    20. Himisha Beltran
    21. Francesca Khani
    22. Mark Pomerantz
    23. Alessandra Dall’Agnese
    24. Jett Crowdis
    25. Eliezer M. Van Allen
    26. Joaquim Bellmunt
    27. Colm Morrisey
    28. Peter S. Nelson
    29. James DeCaprio
    30. Anna Farago
    31. Nicholas Dyson
    32. Benjamin Drapkin
    33. X. Shirley Liu
    34. Matthew Freedman
    35. Michael C. Haffner
    36. Eva Corey
    37. Myles Brown
    38. Henry W. Long

    Reviewed by PREreview

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  4. Gender, Race and Parenthood Impact Academic Productivity During the COVID-19 Pandemic: From Survey to Action

    This article has 17 authors:
    1. Fernanda Staniscuaski
    2. Livia Kmetzsch
    3. Rossana C. Soletti
    4. Fernanda Reichert
    5. Eugenia ZandonĂ 
    6. Zelia M. C. Ludwig
    7. Eliade F. Lima
    8. Adriana Neumann
    9. Ida V. D. Schwartz
    10. Pamela B. Mello-Carpes
    11. Alessandra S. K. Tamajusuku
    12. Fernanda P. Werneck
    13. Felipe K. Ricachenevsky
    14. Camila Infanger
    15. Adriana Seixas
    16. Charley C. Staats
    17. Leticia de Oliveira

    Reviewed by PREreview, ScreenIT

    This article has 2 evaluationsAppears in 2 listsLatest version Latest activity
  5. Studying the Fate of Tumor Extracellular Vesicles at High Spatiotemporal Resolution Using the Zebrafish Embryo

    This article has 24 authors:
    1. Vincent Hyenne
    2. Shima Ghoroghi
    3. Mayeul Collot
    4. Joanna Bons
    5. Gautier Follain
    6. Sébastien Harlepp
    7. Benjamin Mary
    8. Jack Bauer
    9. Luc Mercier
    10. Ignacio Busnelli
    11. Olivier Lefebvre
    12. Nina Fekonja
    13. Maria J. Garcia-Leon
    14. Pedro Machado
    15. François Delalande
    16. Ana Amor LĂłpez
    17. Susana Garcia Silva
    18. Frederik J. Verweij
    19. Guillaume van Niel
    20. Farida Djouad
    21. Héctor Peinado
    22. Christine Carapito
    23. Andrey S. Klymchenko
    24. Jacky G. Goetz

    Reviewed by PREreview

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity
  6. Uncovering the Hidden Antibiotic Potential of Cannabis

    This article has 9 authors:
    1. Maya A. Farha
    2. Omar M. El-Halfawy
    3. Robert T. Gale
    4. Craig R. MacNair
    5. Lindsey A. Carfrae
    6. Xiong Zhang
    7. Nicholas G. Jentsch
    8. Jakob Magolan
    9. Eric D. Brown

    Reviewed by PREreview

    This article has 2 evaluationsAppears in 1 listLatest version Latest activity