@Godwyns26's - a lay man's list of easy-to-understand science made possible by evaluations.

A list by Godwyns Onwuchekwa

So I'm a non scientist using Sciety to gather evaluations that makes the science easier for a lay person to grasp. My previous list is here: https://sciety.org/lists/d64b6bba-a94e-43ad-853c-c03c6825739c @Godwyns26

25 articlesLast updated

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  1. The costs of competition: high social status males experience accelerated epigenetic aging in wild baboons

    1. Jordan A. Anderson
    2. Rachel A. Johnston
    3. Amanda J. Lea
    4. Fernando A. Campos
    5. Tawni N. Voyles
    6. Mercy Y. Akinyi
    7. Susan C. Alberts
    8. Elizabeth A. Archie
    9. Jenny Tung

    • Curated by eLife

      Evaluation Summary:

      In this paper, the authors collect epigenomic data from a well-studied wild baboon community, which they use to construct an epigenetic clock, a method of measuring "biological age" that is increasingly used as a tool in human aging research. The authors find that deviations between biological and chronological age can in part be explained by social phenomena. In particular, for male baboons, maintaining social dominance may play an important role in accelerating the dimension of aging indexed by this measure. This is a foundational study for social-biological-health research.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 and Reviewer #2 agreed to share their names with the authors.)

    Reviewed by eLife

    3 evaluationsAppears in 4 listsLatest version Latest activity

  2. Epidemiology of Road Traffic Accidents and Injuries in Nigeria: A Protocol for Systematic Review and Meta-analysis

    1. Samuel Osobuchi Ngene
    2. Olatoun Adefunke Adeola
    3. Chi-kadibia T Ukoma
    4. Augustine Nwakuche Duru
    5. Kayode Olaoluwa Olaniyan
    6. Chinemerem Eunice Onwuchekwa
    7. Chinonyelum Thecla Ezeonu
    8. Jonathan Chi Daboer
    9. Chioma Laura Odimegwu
    10. Peter Chika Iloanya
    11. Helen Chioma Okoye
    12. Richard Chinaza Ikeagwulonu
    13. Uzoma Vivian Asiegbu
    14. Amaka Obiageli Nnamani
    15. Ifeoma Joy Okoye
    16. Emmanuel Okechukwu Nna
    Appears in 1 list

  3. Advancing the culture of peer review with preprints

    1. Michele Avissar-Whiting
    2. Frederique Belliard
    3. Stefano M Bertozzi
    4. Amy Brand
    5. Katherine Brown
    6. Géraldine Clément-Stoneham
    7. Stephanie Dawson
    8. Gautam Dey
    9. Daniel Ecer
    10. Scott C Edmunds
    11. Tara D. Fischer
    12. Ashley Farley
    13. Maryrose Franko
    14. James Fraser
    15. Kathryn Funk
    16. Clarisse Ganier
    17. Melissa Harrison
    18. Anna Hatch
    19. Haley Hazlett
    20. Samantha Hindle
    21. Daniel W Hook
    22. Phil Hurst
    23. Sophien Kamoun
    24. Robert Kiley
    25. Michael M Lacy
    26. Marcel LaFlamme
    27. Rebecca Lawrence
    28. Thomas Lemberger
    29. Maria Leptin
    30. Elliott Lumb
    31. Catriona MacCallum
    32. Christopher Steven Marcum
    33. Gabriele Marinello
    34. Alex Mendonça
    35. Sara Monaco
    36. Kleber Neves
    37. Damian Pattinson
    38. Jessica Polka
    39. Iratxe Puebla
    40. Martyn Rittman
    41. Stephen J. Royle
    42. Daniela Saderi
    43. Richard Sever
    44. Kathleen Shearer
    45. John Spiro
    46. Bodo Stern
    47. Dario Taraborelli
    48. Ron Vale
    49. Claudia Vasquez
    50. Ludo Waltman
    51. Fiona Watt
    52. Zara Y. Weinberg
    53. Mark Williams
    Appears in 5 lists

  4. Resource allocation strategies for insecticide-treated bed nets to achieve malaria eradication

    1. Nora Schmit
    2. Hillary M Topazian
    3. Matteo Pianella
    4. Giovanni D Charles
    5. Peter Winskill
    6. Michael T White
    7. Katharina Hauck
    8. Azra C Ghani

    • Curated by eLife

      eLife assessment

      This study presents a valuable finding on the optimal prioritization in different malaria transmission settings for the distribution of insecticide-treated nets to reduce the malaria burden. The evidence supporting the claims of the authors is solid, although the authors have made various simplifications to enable the identification of optimal strategies. The work will be of interest from a global funder perspective, though somewhat less relevant for individual countries.

    Reviewed by eLife

    4 evaluationsAppears in 3 listsLatest version Latest activity

  5. Persistence of intact HIV-1 proviruses in the brain during antiretroviral therapy

    1. Weiwei Sun
    2. Yelizaveta Rassadkina
    3. Ce Gao
    4. Sarah Isabel Collens
    5. Xiaodong Lian
    6. Isaac H. Solomon
    7. Shibani Mukerji
    8. Xu G. Yu
    9. Mathias Lichterfeld

    • Curated by eLife

      eLife assessment

      This important study uses near full-length HIV-1 sequencing to examine proviral persistence in various tissues derived from three individuals who received antiretroviral therapy until time of death. Intact as well as defective HIV-1 proviruses are found at various anatomical sites including the central nervous system; the results are convincing and relevant for our understanding of latent viral reservoirs, especially in the brain.

    Reviewed by eLife

    7 evaluationsAppears in 3 listsLatest version Latest activity

  15. Modulation of Neural Networks and Symptom Correlated in Fibromyalgia: A Randomized Double-blind Factorial Explanatory Clinical Trial of Home-Based Transcranial Direct Current Stimulation

    1. Rael Lopes Alves
    2. Maxciel Zortea
    3. Paul Vicuña Serrano
    4. Vani dos Santos Laranjeira
    5. Betina Franceschini Tocchetto
    6. Leticia Ramalho
    7. Camila Fernanda da Silveira Alves
    8. Rafaela Brugnera Tomedi
    9. Rodrigo Pereira de Almeida
    10. Samara Machado Bruck
    11. Liciane Medeiros
    12. Paulo R. S. Sanches
    13. Danton P. Silva
    14. Iraci Lucena da Silva Torres
    15. Felipe Fregni
    16. Wolnei Caumo
    Appears in 1 listLatest version

  16. Cellular Mechanisms Underlying Central Sensitization in a Mouse Model of Chronic Muscle Pain

    1. Yu-Ling Lin
    2. Zhu-Sen Yang
    3. Wai-Yi Wong
    4. Shih-Che Lin
    5. Shuu-Jiun Wang
    6. Shih-Pin Chen
    7. Jen-Kun Cheng
    8. Hui Lu
    9. Cheng-Chang Lien

    • Curated by eLife

      Evaluation Summary:

      This manuscript explores the role of the central amygdala (CeA) on the mechanisms underlying chronic pain. An acid-induced muscle pain (AIMP) mouse model was used. The authors report a key pro-nociception role of CeA Somatostatin (SST) expressing neurons. The central sensitization of CeA-SST neurons was blocked by pregabalin. This work also further highlights the opposing view of the roles of CeA-SST neurons compared to CeA-PKCd neurons in modulating pain-related behaviors. This work will likely have a significant impact in the field and reconciles different previous results.

      (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. Reviewer #1 agreed to share their name with the authors.)

    Reviewed by eLife

    4 evaluationsAppears in 3 listsLatest version Latest activity

  18. Nosocomial outbreak of SARS-CoV-2 in a “non-COVID-19” hospital ward: virus genome sequencing as a key tool to understand cryptic transmission

    1. VĂ­tor Borges
    2. Joana Isidro
    3. Filipe Macedo
    4. José Neves
    5. LuĂ­s Silva
    6. Mário Paiva
    7. José Barata
    8. Judite Catarino
    9. Liliana Ciobanu
    10. SĂ­lvia Duarte
    11. LuĂ­s Vieira
    12. Raquel Guiomar
    13. JoĂŁo Paulo Gomes

    Reviewed by NCRC, ScreenIT

    2 evaluationsAppears in 5 listsLatest version Latest activity

  19. APEX-Gold: A genetically-encoded particulate marker for robust 3D electron microscopy

    1. James Rae
    2. Charles Ferguson
    3. Nicholas Ariotti
    4. Richard I. Webb
    5. Han-Hao Cheng
    6. James L. Mead
    7. Jamie Riches
    8. Dominic J.B. Hunter
    9. Nick Martel
    10. Joanne Baltos
    11. Arthur Christopoulos
    12. Nicole S. Bryce
    13. Maria Lastra Cagigas
    14. Sachini Fonseka
    15. Edna C. Hardeman
    16. Peter W. Gunning
    17. Yann Gambin
    18. Thomas Hall
    19. Robert G. Parton

    • Curated by eLife

      Summary: The manuscript by Rae et al. reports a new protocol for labeling genetically-tagged proteins of interest with heavy atom particles for visualization by electron microscopy. The optimized protocol builds on the use of the enzyme APEX2, fused to the target protein of interest. The contrast enhancement may be useful in diverse 3D EM techniques. Also, reviewers were enthusiastic about the prospects for quantitative studies, even for low-levels of endogenous expression. Semi-quantitative studies may be enabled because the new method appears to improve the proportionality of the signal such that the number of APEX2 tags in a sample correlates with the number of heavy atom particles. The apparent simplicity of the protocol raises the potential for it to become a standard in the field of EM labeling.

      Reviewer #1, Reviewer #2 and Reviewer #3 opted to reveal their name to the authors in the decision letter after review.

    Reviewed by eLife

    4 evaluationsAppears in 4 listsLatest version Latest activity

  20. Sequencing SARS-CoV-2 Genomes from Saliva

    1. Tara Alpert
    2. Chantal B.F. Vogels
    3. Mallery I. Breban
    4. Mary E. Petrone
    5. Yale IMPACT Research Team
    6. Anne L. Wyllie
    7. Nathan D. Grubaugh
    8. Joseph R. Fauver

    Reviewed by ScreenIT

    1 evaluationAppears in 3 listsLatest version Latest activity
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