ScreenIT

Latest preprint reviews

1. The cellular characterisation of SARS-CoV-2 spike protein in virus-infected cells using Receptor Binding Domain-binding specific human monoclonal antibodies

   This article has 14 authors:

   1. Conrad En-Zuo Chan
   2. Ching-Ging Ng
   3. Angeline Pei-Chew Lim
   4. Shirley Lay-Kheng Seah
   5. De-Hoe Chye
   6. Steven Ka-Khuen Wong
   7. Jie-Hui Lim
   8. Vanessa Zi-Yun Lim
   9. Soak-Kuan Lai
   10. Pui-San Wong
   11. Kok-Mun Leong
   12. Yi-Chun Liu
   13. Richard J Sugrue
   14. Boon-Huan Tan

   Reviewed by ScreenIT

2. Survival and outcomes of tocilizumab use in severe and critically ill COVID-19 patients not responding to steroids

   This article has 6 authors:

   1. Shiraz Assu
   2. Deepak Bhasin
   3. Kavita Sekhri
   4. Supriya Sampley
   5. Harpal Singh
   6. Gurleen Kaur

   Reviewed by ScreenIT

3. Selection for infectivity profiles in slow and fast epidemics, and the rise of SARS-CoV-2 variants

   This article has 5 authors:

   1. François Blanquart
   2. Nathanaël Hozé
   3. Benjamin John Cowling
   4. Florence Débarre
   5. Simon Cauchemez

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     This manuscript will be of broad interest to readers interested in understanding characteristics of variants in ongoing epidemics that lead to faster (or slower) growth rates, and will be of particular interest to those wishing to understand the factors leading to selection of SARS-CoV-2 variants. The transmission advantage of a novel strain of a pathogen depends not only on its relative transmissibility, but also on its generation time relative to other strains; the relation between transmissibility, transmission advantage and generation time changes across different phases of the epidemic, enabling statistical inferences to be made about both the transmissibility advantage and generation time of an emerging variant. The method is supported by simulation studies and applied to the Alpha and Delta SARS-CoV-2 variants to show that selection was likely driven by changes in transmissibility rather than changes in the generation time.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

   Reviewed by eLife, ScreenIT

4. Characterization of the interaction between SARS-CoV-2 Membrane Protein and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target

   This article has 18 authors:

   1. Érika Pereira Zambalde
   2. Isadora Carolina Betim Pavan
   3. Mariana Camargo Silva Mancini
   4. Matheus Brandemarte Severino
   5. Orlando Bonito Scudero
   6. Ana Paula Morelli
   7. Mariene Ribeiro Amorim
   8. Karina Bispo dos Santos
   9. Mariana Marcela Góis
   10. Daniel Augusto de Toledo-Teixeira
   11. Pierina Lorencini Parise
   12. Thais Mauad
   13. Marisa Dolhnikoff
   14. Paulo Hilário Nascimento Saldiva
   15. Henrique Marques-Souza
   16. José Luiz Proenca-Modena
   17. Armando Morais Ventura
   18. Fernando Moreira Simabuco

   Reviewed by ScreenIT

5. Production of novel Spike truncations in Chinese hamster ovary cells

   This article has 9 authors:

   1. Shiaki A. Minami
   2. Seongwon Jung
   3. Yihan Huang
   4. Bradley S. Harris
   5. Matthew W. Kenaston
   6. Roland Faller
   7. Somen Nandi
   8. Karen A. McDonald
   9. Priya S. Shah

   Reviewed by ScreenIT

6. Intranasal Immunization with a Vaccinia Virus Vaccine Vector Expressing Pre-Fusion Stabilized SARS-CoV-2 Spike Fully Protected Mice against Lethal Challenge with the Heavily Mutated Mouse-Adapted SARS2-N501YMA30 Strain of SARS-CoV-2

   This article has 10 authors:

   1. Karen V. Kibler
   2. Mateusz Szczerba
   3. Douglas Lake
   4. Alexa J. Roeder
   5. Masmudur Rahman
   6. Brenda G. Hogue
   7. Lok-Yin Roy Wong
   8. Stanley Perlman
   9. Yize Li
   10. Bertram L. Jacobs

   Reviewed by ScreenIT

7. The influence of new SARS-CoV-2 variant Omicron (B.1.1.529) on vaccine efficacy, its correlation to Delta variants: A computational approach

   This article has 5 authors:

   1. Prashant Ranjan
   2. Neha
   3. Chandra Devi
   4. Kaaviyapriya Arulmozhi Devar
   5. Parimal Das

   Reviewed by ScreenIT

8. The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation

   This article has 28 authors:

   1. Tiziana Ginex
   2. Clara Marco-Marín
   3. Miłosz Wieczór
   4. Carlos P. Mata
   5. James Krieger
   6. Paula Ruiz-Rodriguez
   7. Maria Luisa López-Redondo
   8. Clara Francés-Gómez
   9. Roberto Melero
   10. Carlos Óscar Sánchez-Sorzano
   11. Marta Martínez
   12. Nadine Gougeard
   13. Alicia Forcada-Nadal
   14. Sara Zamora-Caballero
   15. Roberto Gozalbo-Rovira
   16. Carla Sanz-Frasquet
   17. Rocío Arranz
   18. Jeronimo Bravo
   19. Vicente Rubio
   20. Alberto Marina
   21. The IBV-Covid19-Pipeline
   22. Ron Geller
   23. Iñaki Comas
   24. Carmen Gil
   25. Mireia Coscolla
   26. Modesto Orozco
   27. José Luis Llácer
   28. Jose-Maria Carazo

   Reviewed by ScreenIT

9. Dynamic analysis and evaluation of asymptomatic infection in the spread of COVID-19

   This article has 4 authors:

   1. Chuanqing Xu
   2. Zonghao Zhang
   3. Xiaotong Huang
   4. Jingan Cui

   Reviewed by ScreenIT

10. Relative contribution of leaving home for work or education, transport, shopping and other activities on risk of acquiring COVID-19 infection outside the household in the second wave of the pandemic in England and Wales

    This article has 15 authors:

    1. S Hoskins
    2. S Beale
    3. RW Aldridge
    4. AMD Navaratnam
    5. C Smith
    6. CE French
    7. A Yavlinsky
    8. V Nguyen
    9. T Byrne
    10. J Kovar
    11. E Fragaszy
    12. WLA Fong
    13. C Geismar
    14. P Patel
    15. AM Johnson

    Reviewed by ScreenIT