The influence of new SARS-CoV-2 variant Omicron (B.1.1.529) on vaccine efficacy, its correlation to Delta variants: A computational approach

  1. Prashant Ranjan
  2. Neha
  3. Chandra Devi
  4. Kaaviyapriya Arulmozhi Devar
  5. Parimal Das

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Abstract

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  1. Version published to 10.1016/j.micpath.2022.105619
  2. ScreenIT

    SciScore for 10.1101/2021.12.06.471215: (What is this?)

    Please note, not all rigor criteria are appropriate for all manuscripts.

    Table 1: Rigor

    NIH rigor criteria are not applicable to paper type.

    Table 2: Resources

    Antibodies
    SentencesResources
    LigPlot plus v2.2 was used to view protein-protein and antibody-protein interactions34.
    antibody-protein interactions34
    suggested: None
    Software and Algorithms
    SentencesResources
    2.4 Docking analysis: The PatchDock server 32,33 was used to dock RBD mutant variants with specified targets (ACE2R and distinct five monoclonal antibody structures), with an RMSD of 4.0 and complex type as default.
    PatchDock
    suggested: (PatchDock, RRID:SCR_017589)

    Results from OddPub: We did not detect open data. We also did not detect open code. Researchers are encouraged to share open data when possible (see Nature blog).

    Results from LimitationRecognizer: An explicit section about the limitations of the techniques employed in this study was not found. We encourage authors to address study limitations.

    Results from TrialIdentifier: No clinical trial numbers were referenced.

    Results from Barzooka: We did not find any issues relating to the usage of bar graphs.

    Results from JetFighter: We did not find any issues relating to colormaps.

    Results from rtransparent:
    • Thank you for including a conflict of interest statement. Authors are encouraged to include this statement when submitting to a journal.
    • Thank you for including a funding statement. Authors are encouraged to include this statement when submitting to a journal.
    • No protocol registration statement was detected.

    Results from scite Reference Check: We found no unreliable references.

    About SciScore

    SciScore is an automated tool that is designed to assist expert reviewers by finding and presenting formulaic information scattered throughout a paper in a standard, easy to digest format. SciScore checks for the presence and correctness of RRIDs (research resource identifiers), and for rigor criteria such as sex and investigator blinding. For details on the theoretical underpinning of rigor criteria and the tools shown here, including references cited, please follow this link.

  3. Version published to 10.1101/2021.12.06.471215v1 on bioRxiv