PREreview

Latest preprint reviews

1. iGABASnFR2: Improved genetically encoded protein sensors of GABA

   This article has 19 authors:

   1. Ilya Kolb
   2. Jeremy P Hasseman
   3. Akihiro Matsumoto
   4. Thomas P Jensen
   5. Olga Kopach
   6. Benjamin J Arthur
   7. Yan Zhang
   8. Arthur Tsang
   9. Daniel Reep
   10. Getahun Tsegaye
   11. Jihong Zheng
   12. Ronak H Patel
   13. Loren L Looger
   14. Jonathan S Marvin
   15. Wyatt L Korff
   16. Dmitri A Rusakov
   17. Keisuke Yonehara
   18. GENIE Project Team
   19. Glenn C Turner

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This manuscript reports the development and characterization of iGABASnFR2, a genetically encoded GABA sensor that demonstrates substantially improved performance compared to its predecessor, iGABASnFR1. The work is comprehensive and methodologically rigorous, combining high-throughput mutagenesis, functional screening, structural analysis, biophysical characterization, and in vivo validation. The significance of the findings is fundamental, and the supporting evidence is compelling. iGABASnFR2 represents a notable advance in GABA sensor engineering, enabling enhanced imaging of GABA transmission both in brain slices and in vivo, and constitutes a timely, technically robust addition to the molecular toolkit for neuroscience research.

   Reviewed by eLife, PREreview

2. Open data in autism research: the views of autistic people and parents of autistic children

   This article has 7 authors:

   1. Hannah Hobson
   2. Amy Pearson
   3. Audrey Helen Linden
   4. Catherine Manning
   5. Felicity Sedgewick
   6. Laura Crane
   7. Daniel Poole

   Reviewed by PREreview

3. RNA triggers chronic stress during neuronal aging

   This article has 12 authors:

   1. Kevin Rhine
   2. Elle Epstein
   3. Natasha M. Carlson
   4. Xuezhen Ge
   5. Orel Mizrahi
   6. Anika Kamat
   7. Anita Hermann
   8. William R. Brothers
   9. John Ravits
   10. Eric J. Bennett
   11. Gülçin Pekkurnaz
   12. Gene W. Yeo

   Reviewed by PREreview

4. Intrinsic Resistance of the Hippocampal CA2 Subfield to Neuroinflammation After Status Epilepticus

   This article has 3 authors:

   1. Bruno Ponciano Da silva
   2. Edna Cristina Santos Franco
   3. Silene Maria Araújo de Lima

   Reviewed by PREreview

5. DESAFIOS E OPORTUNIDADES DOS ESTUDANTES DO ENSINO A DISTÂNCIA (EaD) EM ANGOLA

   This article has 2 authors:

   1. Emanuel Jamba Ferreira
   2. Cireneu de Jesus André Francisco

   Reviewed by PREreview

6. Phase-Space Dynamics Reveal Structured and Chaotic Motility in Human Sperm via DTW Clustering

   This article has 3 authors:

   1. Athanasia Sergounioti
   2. Efstathios Alonaris
   3. Dimitrios Rigas

   Reviewed by PREreview

7. School Librarians’ AI Literacy, Readiness and Professional Engagement with AI Technologies: An International Survey

   This article has 3 authors:

   1. Zakir Hossain
   2. Corinne Hertel
   3. Md. Sakib Biswas

   Reviewed by PREreview

8. Chronobot: Deep learning guided time-resolved cryo-EM captures molecular choreography of RecA in homology search

   This article has 8 authors:

   1. Märt-Erik Mäeots
   2. Simon Tupin
   3. Mohammad M. N. Esfahani
   4. Juan B. Rodriguez Molina
   5. Julie A. Clapperton
   6. Aran Amin
   7. Albane Imbert
   8. Radoslav I. Enchev

   Reviewed by PREreview

9. Coxsackievirus A24: A Causative Agent of Acute Haemorrhagic Conjunctivitis Outbreak in Dar es Salaam, Tanzania, between January and February 2024

   This article has 21 authors:

   1. Lawrence A. Mapunda
   2. Peter van Heusden
   3. Robert Baluhya
   4. Olympia G. Machange
   5. Ambele Mwafulango
   6. Monica Fredrick Francis
   7. Aziz Ituka
   8. Omega Machange
   9. Adela Kisanga
   10. Edna E. Mgimba
   11. Hamza H. Matimba
   12. Dennis M. Kado
   13. Elson E. Kimaro
   14. Ramadhani A. Libenanga
   15. Jackson Peter Mushumbusi
   16. Hamisi M. Swalehe
   17. Ibrahim Mauki
   18. James Hellar
   19. Shimba Henerico
   20. Maria E. Kelly
   21. Nyambura Moremi

   Reviewed by PREreview

10. SafeSurf Darknet 2025: A Novel Dataset for Darknet Traffic Detection and Analysis

    This article has 5 authors:

    1. Qasem Abu Al-Haija
    2. Mohammad J. Obaidat
    3. Ibrahim A. Al-Syouf
    4. Yahea F. Awawdeh
    5. Anas E. Masa’deh

    Reviewed by PREreview