PREreview

Latest preprint reviews

1. Structure of SARS-CoV-2 M protein in lipid nanodiscs

   This article has 6 authors:

   1. Kimberly A Dolan
   2. Mandira Dutta
   3. David M Kern
   4. Abhay Kotecha
   5. Gregory A Voth
   6. Stephen G Brohawn

   This article has been curated by 1 group:

   • Curated by eLife

     Evaluation Summary:

     This paper reports the structure of the M protein of SARS-CoV-2, as determined by cryoEM. The structure is well-determined and reveals a homodimer with overall similar structure as ORF3a, another virally encoded protein. The surface charge distribution is skewed towards positive at the C-terminal domain, which suggests roles in interactions with viral N and S proteins, and possibly viral RNA. The work is of relevance to virologists, especially those studying SARS-CoV-2.

     (This preprint has been reviewed by eLife. We include the public reviews from the reviewers here; the authors also receive private feedback with suggested changes to the manuscript. The reviewers remained anonymous to the authors.)

   Reviewed by eLife, PREreview

2. Fat body-specific reduction of CTPS alleviates HFD-induced obesity

   This article has 5 authors:

   1. Jingnan Liu
   2. Yuanbing Zhang
   3. Qiao-Qi Wang
   4. Youfang Zhou
   5. Ji-Long Liu

   Reviewed by PREreview

3. Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis

   This article has 11 authors:

   1. Malini Mukherjee
   2. Ishara Ratnayake
   3. Madhusudhana Janga
   4. Eric Fogarty
   5. Shania Scheidt
   6. Justin Grassmeyer
   7. Jennifer deRiso
   8. Indra Chandrasekar
   9. Phil Ahrenkiel
   10. Raphael Kopan
   11. Kameswaran Surendran

   Reviewed by PREreview

4. Ataxin-7 promotes Drosophila posterior follicle cell maturation by suppressing yorkie function

   This article has 2 authors:

   1. Hammed Badmos
   2. Daimark Bennett

   Reviewed by PREreview

5. Transcription Factor EB regulates phosphatidylinositol-3-phosphate levels on endomembranes and alters lysosome positioning in the bladder cancer model

   This article has 7 authors:

   1. Pallavi Mathur
   2. Camilla De Barros Santos
   3. Hugo Lachuer
   4. Bruno Latgé
   5. François Radvanyi
   6. Bruno Goud
   7. Kristine Schauer

   Reviewed by PREreview

6. Platelet transcription factors license the pro-inflammatory cytokine response of human monocytes

   This article has 17 authors:

   1. Ibrahim Hawwari
   2. Lukas Rossnagel
   3. Nathalia Rosero
   4. Salie Maasewerd
   5. Matilde B Vasconcelos
   6. Marius Jentzsch
   7. Agnieszka Demczuk
   8. Lino L Teichmann
   9. Lisa Meffert
   10. Damien Bertheloot
   11. Lucas S Ribeiro
   12. Sebastian Kallabis
   13. Felix Meissner
   14. Moshe Arditi
   15. Asli E Atici
   16. Magali Noval Rivas
   17. Bernardo S Franklin

   Reviewed by PREreview

7. Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade

   This article has 48 authors:

   1. Assaf Magen
   2. Pauline Hamon
   3. Nathalie Fiaschi
   4. Leanna Troncoso
   5. Etienne Humblin
   6. Darwin D’souza
   7. Travis Dawson
   8. Matthew D. Park
   9. Joel Kim
   10. Steven Hamel
   11. Mark Buckup
   12. Christie Chang
   13. Alexandra Tabachnikova
   14. Hara Schwartz
   15. Nausicaa Malissen
   16. Yonit Lavin
   17. Alessandra Soares-Schanoski
   18. Bruno Giotti
   19. Samarth Hegde
   20. Raphaël Mattiuz
   21. Clotilde Hennequin
   22. Jessica Le Berichel
   23. Zhen Zhao
   24. Stephen Ward
   25. Isabel Fiel
   26. Colles Price
   27. Nicolas Fernandez
   28. Jiang He
   29. Baijun Kou
   30. Michael Dobosz
   31. Lianjie Li
   32. Christina Adler
   33. Min Ni
   34. Yi Wei
   35. Wei Wang
   36. Namita T. Gupta
   37. Kunal Kundu
   38. Kamil Cygan
   39. Raquel P. Deering
   40. Alex Tsankov
   41. Seunghee Kim-Schulze
   42. Sacha Gnjatic
   43. Ephraim Kenigsberg
   44. Myron Schwartz
   45. Thomas U. Marron
   46. Gavin Thurston
   47. Alice O. Kamphorst
   48. Miriam Merad

   Reviewed by PREreview

8. COVID-19 risk score as a public health tool to guide targeted testing: A demonstration study in Qatar

   This article has 19 authors:

   1. Laith J. Abu-Raddad
   2. Soha Dargham
   3. Hiam Chemaitelly
   4. Peter Coyle
   5. Zaina Al Kanaani
   6. Einas Al Kuwari
   7. Adeel A. Butt
   8. Andrew Jeremijenko
   9. Anvar Hassan Kaleeckal
   10. Ali Nizar Latif
   11. Riyazuddin Mohammad Shaik
   12. Hanan F. Abdul Rahim
   13. Gheyath K. Nasrallah
   14. Hadi M. Yassine
   15. Mohamed G. Al Kuwari
   16. Hamad Eid Al Romaihi
   17. Mohamed H. Al-Thani
   18. Abdullatif Al Khal
   19. Roberto Bertollini

   Reviewed by PREreview, ScreenIT

9. Attenuation of a DNA Cruciform by a Conserved Regulator Directs T3SS-1 mediated virulence in Vibrio parahaemolyticus

   This article has 6 authors:

   1. Landon J. Getz
   2. Justin M. Brown
   3. Lauren Sobot
   4. Alexandra Chow
   5. Jastina Mahendrarajah
   6. Nikhil A. Thomas

   Reviewed by PREreview

10. Comparison of urine proteomes from tumor-bearing mice with those from tumor-resected mice

    This article has 3 authors:

    1. Heng Ziqi
    2. Zhao Chenyang
    3. Gao Youhe

    Reviewed by PREreview