preLights

Latest preprint reviews

1. FoxO transcription factors actuate the formative pluripotency specific gene expression programme

   This article has 8 authors:

   1. Laura Santini
   2. Saskia Kowald
   3. Luis Miguel Cerron-Alvan
   4. Michelle Huth
   5. Anna Philina Fabing
   6. Giovanni Sestini
   7. Nicolas Rivron
   8. Martin Leeb

   Reviewed by preLights

2. Digital Microbe: A Genome-Informed Data Integration Framework for Collaborative Research on Emerging Model Organisms

   This article has 16 authors:

   1. Iva Veseli
   2. Michelle A. DeMers
   3. Zachary S. Cooper
   4. Matthew S. Schechter
   5. Samuel Miller
   6. Laura Weber
   7. Christa B. Smith
   8. Lidimarie T. Rodriguez
   9. William F. Schroer
   10. Matthew R. McIlvin
   11. Paloma Z. Lopez
   12. Makoto Saito
   13. Sonya Dyhrman
   14. A. Murat Eren
   15. Mary Ann Moran
   16. Rogier Braakman

   Reviewed by preLights

3. Lens placode modulates extracellular matrix formation during early eye development

   This article has 4 authors:

   1. Cecília G. De Magalhães
   2. Ales Cvekl
   3. Ruy G. Jaeger
   4. C.Y. Irene Yan

   Reviewed by preLights

4. DNA methylation enables recurrent endogenization of giant viruses in an animal relative

   This article has 8 authors:

   1. Luke A. Sarre
   2. Iana V. Kim
   3. Vladimir Ovchinnikov
   4. Marine Olivetta
   5. Hiroshi Suga
   6. Omaya Dudin
   7. Arnau Sebé-Pedrós
   8. Alex de Mendoza

   Reviewed by preLights

5. Learning a conserved mechanism for early neuroectoderm morphogenesis

   This article has 9 authors:

   1. Matthew Lefebvre
   2. Jonathan Colen
   3. Nikolas Claussen
   4. Fridtjof Brauns
   5. Marion Raich
   6. Noah Mitchell
   7. Michel Fruchart
   8. Vincenzo Vitelli
   9. Sebastian J Streichan

   Reviewed by preLights

6. Experience-dependent plasticity of a highly specific olfactory circuit in Drosophila melanogaster

   This article has 5 authors:

   1. Benjamin Fabian
   2. Veit Grabe
   3. Rolf G. Beutel
   4. Bill S. Hansson
   5. Silke Sachse

   Reviewed by preLights

7. A direct experimental test of Ohno’s hypothesis

   This article has 8 authors:

   1. Ljiljana Mihajlovic
   2. Bharat Ravi Iyengar
   3. Florian Baier
   4. Içvara Barbier
   5. Justyna Iwaszkiewicz
   6. Vincent Zoete
   7. Andreas Wagner
   8. Yolanda Schaerli

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This fundamental study uses a creative experimental system to directly test Ohno's hypothesis, which describes how and why new genes might evolve by duplication of existing ones. In agreement with existing criticism of Ohno's original idea, the authors present compelling evidence that having two gene copies does not speed up the evolution of a new function as posited by Ohno, but instead leads to the rapid inactivation of one of the copies through the accumulation of mostly deleterious mutations. These findings will be of broad interest to evolutionary biologists and geneticists.

   Reviewed by eLife, preLights

8. Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

   This article has 4 authors:

   1. Maggy Yu Hei Lau
   2. Sana Gadiwalla
   3. Susan Jones
   4. Elisa Galliano

   Reviewed by preLights

9. Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

   This article has 2 authors:

   1. Jayne Aiken
   2. Erika L. F. Holzbaur

   Reviewed by preLights

10. Inference of drug off-target effects on cellular signaling using interactome-based deep learning

    This article has 3 authors:

    1. Nikolaos Meimetis
    2. Douglas A. Lauffenburger
    3. Avlant Nilsson

    Reviewed by preLights