preLights

Latest preprint reviews

1. Learning a conserved mechanism for early neuroectoderm morphogenesis

   This article has 9 authors:

   1. Matthew Lefebvre
   2. Jonathan Colen
   3. Nikolas Claussen
   4. Fridtjof Brauns
   5. Marion Raich
   6. Noah Mitchell
   7. Michel Fruchart
   8. Vincenzo Vitelli
   9. Sebastian J Streichan

   Reviewed by preLights

2. Experience-dependent plasticity of a highly specific olfactory circuit in Drosophila melanogaster

   This article has 5 authors:

   1. Benjamin Fabian
   2. Veit Grabe
   3. Rolf G. Beutel
   4. Bill S. Hansson
   5. Silke Sachse

   Reviewed by preLights

3. A direct experimental test of Ohno’s hypothesis

   This article has 8 authors:

   1. Ljiljana Mihajlovic
   2. Bharat Ravi Iyengar
   3. Florian Baier
   4. Içvara Barbier
   5. Justyna Iwaszkiewicz
   6. Vincent Zoete
   7. Andreas Wagner
   8. Yolanda Schaerli

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This fundamental study uses a creative experimental system to directly test Ohno's hypothesis, which describes how and why new genes might evolve by duplication of existing ones. In agreement with existing criticism of Ohno's original idea, the authors present compelling evidence that having two gene copies does not speed up the evolution of a new function as posited by Ohno, but instead leads to the rapid inactivation of one of the copies through the accumulation of mostly deleterious mutations. These findings will be of broad interest to evolutionary biologists and geneticists.

   Reviewed by eLife, preLights

4. Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

   This article has 4 authors:

   1. Maggy Yu Hei Lau
   2. Sana Gadiwalla
   3. Susan Jones
   4. Elisa Galliano

   Reviewed by preLights

5. Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

   This article has 2 authors:

   1. Jayne Aiken
   2. Erika L. F. Holzbaur

   Reviewed by preLights

6. Inference of drug off-target effects on cellular signaling using interactome-based deep learning

   This article has 3 authors:

   1. Nikolaos Meimetis
   2. Douglas A. Lauffenburger
   3. Avlant Nilsson

   Reviewed by preLights

7. Hibernating ribosomes tether to mitochondria as an adaptive response to cellular stress during glucose depletion

   This article has 8 authors:

   1. Olivier Gemin
   2. Maciej Gluc
   3. Michael Purdy
   4. Higor Rosa
   5. Moritz Niemann
   6. Yelena Peskova
   7. Simone Mattei
   8. Ahmad Jomaa

   Reviewed by preLights

8. Structured RhoGEF recruitment drives myosin II organization on large exocytotic vesicles

   This article has 5 authors:

   1. Kumari Kamalesh
   2. Dagan Segal
   3. Ori Avinoam
   4. Eyal D. Schejter
   5. Ben-Zion Shilo

   Reviewed by preLights

9. The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

   This article has 12 authors:

   1. Hasan Mamar
   2. Roberta Fajka-Boja
   3. Mónika Mórocz
   4. Eva Pinto Jurado
   5. Siham Zentout
   6. Alexandra Mihuț
   7. Anna Georgina Kopasz
   8. Mihály Mérey
   9. Rebecca Smith
   10. Lajos Haracska
   11. Sébastien Huet
   12. Gyula Timinszky

   Reviewed by preLights

10. Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories

    This article has 47 authors:

    1. Jeanette A.I. Johnson
    2. Daniel R. Bergman
    3. Heber L. Rocha
    4. David L. Zhou
    5. Eric Cramer
    6. Ian C. Mclean
    7. Yoseph W. Dance
    8. Max Booth
    9. Zachary Nicholas
    10. Tamara Lopez-Vidal
    11. Atul Deshpande
    12. Randy Heiland
    13. Elmar Bucher
    14. Fatemeh Shojaeian
    15. Matthew Dunworth
    16. André Forjaz
    17. Michael Getz
    18. Inês Godet
    19. Furkan Kurtoglu
    20. Melissa Lyman
    21. John Metzcar
    22. Jacob T. Mitchell
    23. Andrew Raddatz
    24. Jacobo Solorzano
    25. Aneequa Sundus
    26. Yafei Wang
    27. David G. DeNardo
    28. Andrew J. Ewald
    29. Daniele M. Gilkes
    30. Luciane T. Kagohara
    31. Ashley L. Kiemen
    32. Elizabeth D. Thompson
    33. Denis Wirtz
    34. Laura D. Wood
    35. Pei-Hsun Wu
    36. Neeha Zaidi
    37. Lei Zheng
    38. Jacquelyn W. Zimmerman
    39. Jude M. Phillip
    40. Elizabeth M. Jaffee
    41. Joe W. Gray
    42. Lisa M. Coussens
    43. Young Hwan Chang
    44. Laura M. Heiser
    45. Genevieve L. Stein-O’Brien
    46. Elana J. Fertig
    47. Paul Macklin

    Reviewed by preLights