preLights

Latest preprint reviews

1. A zebrafish circuit for behavioral credit assignment

   This article has 4 authors:

   1. Emanuele Paoli
   2. Virginia Palieri
   3. Amey Shenoy
   4. Ruben Portugues

   Reviewed by preLights

2. Scaly-Tail Organ Enhances Static Stability during Pel’s Scaly-tailed Flying Squirrels’ Arboreal Locomotion

   This article has 6 authors:

   1. Andrew K. Schulz
   2. Mrudul Chellapurath
   3. Pranav C. Khandelwal
   4. SeyedReza Rezaei
   5. Stefan Merker
   6. Ardian Jusufi

   Reviewed by preLights

3. Tidyplots empowers life scientists with easy code-based data visualization

   This article has 1 author:

   1. Jan Broder Engler

   Reviewed by preLights

4. Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

   This article has 17 authors:

   1. Claire Masson
   2. Cyril Scandola
   3. Jean-Yves Rinckel
   4. Fabienne Proamer
   5. Emily Janus-Bell
   6. Fareeha Batool
   7. Naël Osmani
   8. Jacky G Goetz
   9. Léa Mallo
   10. Catherine Léon
   11. Alicia Bornert
   12. Renaud Poincloux
   13. Olivier Destaing
   14. Alma Mansson
   15. Hong Qian
   16. Maxime Lehmann
   17. Anita Eckly

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors provide a thorough investigation of the interaction of megakaryocytes (MK) with their associated extracellular matrix (ECM) during maturation; they provide evidence that the existence of a dense cage-like pericellular structure containing laminin γ1 and α4 and collagen IV is key to fixing the perisinusoidal localization of MK and preventing their premature intravasation. Adhesion of MK to this ECM cage is dependent on integrin beta1 and beta3 expressed by MK. This strong and solid conclusion is based on the use of state-of-the art techniques such as the use of primary murine bone marrow MK cultures, mice lacking ECM receptors, namely integrin beta1 and beta3 null mice, as well as high-resolution 2D and 3D imaging. The study provides valuable insight into the role of cell-matrix interactions in MK maturation and provides an interesting model with practical implications for the fields of hemostasis and thrombosis.

   Reviewed by preLights, eLife

5. Discovery of a Potent and Selective Inhibitor of Human NLRP3 with a Novel Binding Modality and Mechanism of Action

   This article has 30 authors:

   1. Kevin Wilhelmsen
   2. Aditi Deshpande
   3. Sarah Tronnes
   4. Maitriyee Mahanta
   5. Matthew Banicki
   6. Mary Cochran
   7. Samantha Cowdin
   8. Kristen Fortney
   9. George Hartman
   10. Robert Hughes
   11. Rusty Montgomery
   12. Claudia Portillo
   13. Paul Rubin
   14. Yan Wang
   15. Shijun Yan
   16. Barry A Morgan
   17. Assem Duisembekova
   18. Romane Riou
   19. Michael Marleaux
   20. Inga V. Hochheiser
   21. Hannes Buthmann
   22. Dominic Ferber
   23. Wei Wang
   24. Melanie Cranston
   25. Chloe M. McKee
   26. Thea Mawhinney
   27. Emma McKay
   28. Bénédicte F. Py
   29. Matthias Geyer
   30. Rebecca C. Coll

   Reviewed by preLights

6. Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons

   This article has 8 authors:

   1. Klaudia Strucinska
   2. Parker Kneis
   3. Travis Pennington
   4. Katarzyna Cizio
   5. Patrycja Szybowska
   6. Abigail Morgan
   7. Joshua Weertman
   8. Tommy L Lewis

   Reviewed by preLights

7. Visually-guided compensation of deafening-induced song deterioration

   This article has 5 authors:

   1. M Rolland
   2. A Zai
   3. RHR Hahnloser
   4. C Del Negro
   5. N Giret

   Reviewed by preLights

8. Mechanical stresses govern myoblast fusion and myotube growth

   This article has 9 authors:

   1. Yoann Le Toquin
   2. Sushil Dubey
   3. Aleksandra Ardaševa
   4. Lakshmi Balasubramaniam
   5. Emilie Delaune
   6. Valérie Morin
   7. Amin Doostmohammadi
   8. Christophe Marcelle
   9. Benoît Ladoux

   Reviewed by preLights

9. IMMClock reveals immune aging and T cell function at single-cell resolution

   This article has 13 authors:

   1. Yael Gurevich Schmidt
   2. Di Wu
   3. Sanna Madan
   4. Sanju Sinha
   5. Sahil Sahni
   6. Vishaka Gopalan
   7. Binbin Wang
   8. Saugato Rahman Dhruba
   9. Alejandro A. Schäffer
   10. Nan-ping Weng
   11. Nicholas P. Restifo
   12. Kun Wang
   13. Eytan Ruppin

   Reviewed by preLights

10. Levetiracetam prevents Aβ42 production through SV2a-dependent modulation of App processing in Alzheimer’s disease models

    This article has 15 authors:

    1. Nalini R. Rao
    2. Olivia DeGulis
    3. Toshihiro Nomura
    4. SeungEun Lee
    5. Timothy J. Hark
    6. Justin C. Dynes
    7. Emily X. Dexter
    8. Maciej Dulewicz
    9. Junyue Ge
    10. Arun Upadhyay
    11. Eugenio F. Fornasiero
    12. Robert Vassar
    13. Jörg Hanrieder
    14. Anis Contractor
    15. Jeffrey N. Savas

    Reviewed by preLights