preLights

Latest preprint reviews

1. Chromatin priming and co-factor availability shape lineage response to the neuronal pioneer factor ASCL1 in pluripotency

   This article has 5 authors:

   1. Jethro Lundie-Brown
   2. Rosalind Drummond
   3. John-Poul Ng-Blichfeldt
   4. Roberta Azzarelli
   5. Anna Philpott

   Reviewed by preLights

2. Generalization and extinction of learned fear alter primary sensory input to the brain

   This article has 3 authors:

   1. Michelle C. Rosenthal
   2. Alper K. Bakir
   3. John P. McGann

   Reviewed by preLights

3. Fear conditioning biases olfactory sensory neuron frequencies across generations

   This article has 9 authors:

   1. Clara W Liff
   2. Yasmine R Ayman
   3. Eliza CB Jaeger
   4. Avery Cardeiro
   5. Hudson S Lee
   6. Alexis Kim
   7. Angelica Vina-Abarracin
   8. Dianne-Lee KD Ferguson
   9. Bianca J Marlin

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study provides solid evidence that odor fear conditioning biases olfactory sensory neuron receptor choice in mice and that this bias is detectable in the next generation. The authors use rigorous histological and behavioral analyses, including unsupervised behavioral quantification, to support the conclusion that odor-specific sensory representations can be shaped by experience and partially transmitted across generations. While the behavioral effects in offspring are modest and the mechanistic basis of inheritance remains unresolved, the study offers an important and carefully executed contribution to understanding experience-dependent sensory plasticity and its intergenerational consequences.

   Reviewed by preLights, eLife

4. Temporal degradation of PRC2 uncovers specific developmental dependencies

   This article has 6 authors:

   1. Ming-Kang Lee
   2. Sebastian D. Mackowiak
   3. Daniel Felismino
   4. Jeron Venhuizen
   5. Maria Walther
   6. Alexander Meissner

   Reviewed by preLights

5. The metabolome and proteome of stem cell-derived human primordial germ cells: a multi-omics approach

   This article has 8 authors:

   1. Madalena Vaz Santos
   2. Bauke V. Schomakers
   3. Marta Llobet Ayala
   4. Tara Jamali
   5. Michel van Weeghel
   6. Ans M. van Pelt
   7. Callista L. Mulder
   8. Geert Hamer

   Reviewed by preLights

6. “Embryo-eggshell interaction counteracts chiral bias in early Drosophila morphogenesis”

   This article has 8 authors:

   1. Giulia Serafini
   2. Maryam Setoudeh
   3. Marina B. Cuenca
   4. Charlène Brillard
   5. Matthias Arzt
   6. Pavel Mejstřik
   7. Pierre A. Haas
   8. Pavel Tomančák

   Reviewed by preLights

7. Cardiac-immune microniches programme macrophage states in the regenerating heart

   This article has 8 authors:

   1. Ehsan Razaghi
   2. Selin Tüzüner
   3. Trishalee Gungoosingh
   4. Kerem Çil
   5. Wan Shern Wong
   6. Rita Alonaizan
   7. Rebecca Richardson
   8. Filipa C. Simões

   Reviewed by preLights

8. Gut microbiome changes over the course of multiple sclerosis differentially influence autoimmune neuroinflammation

   This article has 10 authors:

   1. Amélia Sarmento
   2. Tommy Regen
   3. Daniela Ferro
   4. Ángel Ruiz-Moreno
   5. Cintya González-Torres
   6. Katlynn Carter
   7. Arthi Shanmugavadivu
   8. Ari Waisman
   9. Maria José Sá
   10. Carles Ubeda

   Reviewed by preLights

9. Loss of Sun2 ablates nuclear mechanosensing-driven extracellular matrix production and mitigates lung fibrosis

   This article has 13 authors:

   1. Emma Carley
   2. Sandra Sandria
   3. Xueyan Peng
   4. Kerri Davidson
   5. Aya Nassereddine
   6. Changwan Ryu
   7. Rachel Rivera
   8. John McGovern
   9. Alexander Ghincea
   10. C. Patrick Lusk
   11. Erica L. Herzog
   12. Valerie Horsley
   13. Megan C. King

   Reviewed by preLights

10. Prenatal Stress Differentially Shapes Adult Behavior in Male and Female Offspring

    This article has 4 authors:

    1. Erbo Dong
    2. Alison Chu
    3. Tamar Gur
    4. Stephanie M. Gorka

    Reviewed by preLights