preLights is a community initiative supported by The Company of Biologists.

  1. Similarity metric learning on perturbational datasets improves functional identification of perturbations

    1. Ian Smith
    2. Petr Smirnov
    3. Benjamin Haibe-Kains

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  2. PYCR1 Levels Track with Premature and Chronological Skin Aging

    1. Kortessa Sotiropoulou
    2. Saniye Yumlu
    3. Tomoko Hirano
    4. Michael Maier
    5. Abigail Loh
    6. Peh Fern Ong
    7. Onn Siong Yim
    8. Chunping Liu
    9. Emmanuel Vial
    10. Umut Altunoğlu
    11. Sheela Nampoothiri
    12. Deepthi de Silva
    13. Björn Fischer-Zirnsak
    14. Hülya Kayserili
    15. Poh San Lai
    16. Oliver Dreesen
    17. Kenji Kabashima
    18. Uwe Kornak
    19. Nathalie Escande-Beillard
    20. Bruno Reversade

    • Curated by eLife

      eLife assessment

      This manuscript uses genetic mouse modeling to delve deeper into a rare human disease of aging. The targeted approaches employed lend greater pathophysiologic insight and makes this paper valuable to the field art large. Additionally, the approaches used are rigorous and solid in supporting their conclusions. Some minor weaknesses were noted along with suggestions to add greater clarity.

    Reviewed by preLights, eLife

    4 evaluationsAppears in 4 listsLatest version Latest activity

  3. The landscape of biomedical research

    1. Rita González-Márquez
    2. Luca Schmidt
    3. Benjamin M. Schmidt
    4. Philipp Berens
    5. Dmitry Kobak

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Glycan-specific IgM is critical for human immunity to Staphylococcus aureus

    1. Astrid Hendriks
    2. Priscilla F. Kerkman
    3. Meri R.J. Varkila
    4. Jelle L.G. Haitsma-Mulier
    5. Sara Ali
    6. Thijs ten Doesschate
    7. Thomas W. van der Vaart
    8. Carla J.C. de Haas
    9. Piet C. Aerts
    10. Olaf L. Cremer
    11. Marc J.M. Bonten
    12. Victor Nizet
    13. George Y. Liu
    14. Jeroen D.C. Codée
    15. Suzan H.M. Rooijakkers
    16. Jos A.G. van Strijp
    17. Nina M. van Sorge

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Small extracellular vesicles promote stiffness-mediated metastasis

    1. Alexandra Sneider
    2. Ying Liu
    3. Bartholomew Starich
    4. Wenxuan Du
    5. Carolyn Marar
    6. Najwa Faqih
    7. Gabrielle E. Ciotti
    8. Joo Ho Kim
    9. Sejal Krishnan
    10. Salma Ibrahim
    11. Muna Igboko
    12. Alexus Locke
    13. Daniel M. Lewis
    14. Hanna Hong
    15. Michelle Karl
    16. Raghav Vij
    17. Gabriella C. Russo
    18. Praful Nair
    19. Estibaliz Gómez-de-Mariscal
    20. Mehran Habibi
    21. Arrate Muñoz-Barrutia
    22. Luo Gu
    23. T.S. Karin Eisinger-Mathason
    24. Denis Wirtz

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  6. VEGFA mRNA-LNP promotes biliary epithelial cell-to-hepatocyte conversion in acute and chronic liver diseases and reverses steatosis and fibrosis

    1. Fatima Rizvi
    2. Yu-Ri Lee
    3. Ricardo Diaz-Aragon
    4. Juhoon So
    5. Rodrigo M. Florentino
    6. Anna R. Smith
    7. Elissa Everton
    8. Alina Ostrowska
    9. Kyounghwa Jung
    10. Ying Tam
    11. Hiromi Muramatsu
    12. Norbert Pardi
    13. Drew Weissman
    14. Alejandro Soto-Gutierrez
    15. Donghun Shin
    16. Valerie Gouon-Evans

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  7. An oncogenic isoform of septin 9 promotes the formation of juxtanuclear invadopodia by reducing nuclear deformability

    1. Joshua Okletey
    2. Dimitrios Angelis
    3. Tia M. Jones
    4. Cristina Montagna
    5. Elias T. Spiliotis

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  8. Glial Draper signaling triggers cross-neuron plasticity in bystander neurons after neuronal cell death

    1. Yupu Wang
    2. Ruiling Zhang
    3. Sihao Huang
    4. Parisa Tajalli-Tehrani Valverde
    5. Meike Lobb-Rabe
    6. James Ashley
    7. Lalanti Venkatasubramanian
    8. Robert A. Carrillo

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  9. CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

    1. Avi J. Samelson
    2. Nabeela Ariqat
    3. Justin McKetney
    4. Gita Rohanitazangi
    5. Celeste Parra Bravo
    6. Darrin Goodness
    7. Ruilin Tian
    8. Parker Grosjean
    9. Romany Abskharon
    10. David Eisenberg
    11. Nicholas M. Kanaan
    12. Li Gan
    13. Carlo Condello
    14. Danielle L. Swaney
    15. Martin Kampmann

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Generating human neural diversity with a multiplexed morphogen screen in organoids

    1. Neal D. Amin
    2. Kevin W. Kelley
    3. Jin Hao
    4. Yuki Miura
    5. Genta Narazaki
    6. Tommy Li
    7. Patrick McQueen
    8. Shravanti Kulkarni
    9. Sergey Pavlov
    10. Sergiu P. Paşca

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity
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