preLights is a community initiative supported by The Company of Biologists.

  1. The genome of the colonial hydroid Hydractinia reveals their stem cells utilize a toolkit of evolutionarily shared genes with all animals

    1. Christine E. Schnitzler
    2. E. Sally Chang
    3. Justin Waletich
    4. Gonzalo Quiroga-Artigas
    5. Wai Yee Wong
    6. Anh-Dao Nguyen
    7. Sofia N. Barreira
    8. Liam Doonan
    9. Paul Gonzalez
    10. Sergey Koren
    11. James M. Gahan
    12. Steven M. Sanders
    13. Brian Bradshaw
    14. Timothy Q. DuBuc
    15. Febrimarsa
    16. Danielle de Jong
    17. Eric P. Nawrocki
    18. Alexandra Larson
    19. Samantha Klasfeld
    20. Sebastian G. Gornik
    21. R. Travis Moreland
    22. Tyra G. Wolfsberg
    23. Adam M. Phillippy
    24. James C. Mullikin
    25. Oleg Simakov
    26. Paulyn Cartwright
    27. Matthew Nicotra
    28. Uri Frank
    29. Andreas D. Baxevanis

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  2. TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling.

    1. Luyang Xiong
    2. Irina Zhevlakova
    3. Xiaoxia Z. West
    4. Detao Gao
    5. Rakhylia Murtazina
    6. Anthony Horak
    7. J. Mark Brown
    8. Iuliia Molokotina
    9. Eugene A. Podrez
    10. Tatiana V. Byzova

    • Curated by eLife

      eLife assessment

      In this manuscript by Xiong L et al., through TLR2, the authors have uncovered an important link between innate immune signaling and hair regeneration. The authors provide convincing evidence supporting the critical roles of TLR2 in sensing CEP levels in hair follicles, counteracting the action of BMP signaling, and facilitating the activation of HFSCs during the hair cycle and wound repair. Importantly, the authors also propose that decreased CEP production and TLR2 expression might be factors contributing to the decreased hair regeneration associated with age-related and obesity-related hair thinning and hair loss phenotypes.

    Reviewed by preLights, eLife

    3 evaluationsAppears in 3 listsLatest version Latest activity

  3. Optical Control of G-Actin with a Photoswitchable Latrunculin

    1. Nynke A. Vepřek
    2. Madeline H. Cooper
    3. Laura Laprell
    4. Emily Jie-Ning Yang
    5. Sander Folkerts
    6. Ruiyang Bao
    7. Thomas G. Oertner
    8. Liza A. Pon
    9. J. Bradley Zuchero
    10. Dirk H. Trauner

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  4. Hypoxia blunts angiogenic signaling and upregulates the antioxidant system in elephant seal endothelial cells

    1. Kaitlin N Allen
    2. Julia María Torres-Velarde
    3. Juan Manuel Vazquez
    4. Diana D Moreno-Santillan
    5. Peter H Sudmant
    6. José Pablo Vázquez-Medina

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  5. Mechano-dependent sorbitol accumulation supports biomolecular condensate

    1. Stephanie Torrino
    2. William M Oldham
    3. Andrés R Tejedor
    4. Ignacio S. Burgos
    5. Nesrine Rachedi
    6. Kéren Fraissard
    7. Caroline Chauvet
    8. Chaima Sbai
    9. Brendan P. O’Hara
    10. Sophie Abélanet
    11. Frederic Brau
    12. Stephan Clavel
    13. Rosana Collepardo-Guevara
    14. Jorge R. Espinosa
    15. Issam Ben-Sahra
    16. Thomas Bertero

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  6. CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

    1. Madison B. Adolph
    2. Atharv S. Garje
    3. Swati Balakrishnan
    4. Florian Morati
    5. Mauro Modesti
    6. Walter J. Chazin
    7. David Cortez

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  7. Proteasome condensate formation is driven by multivalent interactions with shuttle factors and K48-linked ubiquitin chains

    1. Kenrick A. Waite
    2. Gabrielle Vontz
    3. Stella Y. Lee
    4. Jeroen Roelofs

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  8. A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks

    1. Song Feng
    2. James A. Sanford
    3. Thomas Weber
    4. Chelsea M. Hutchinson-Bunch
    5. Panshak P. Dakup
    6. Vanessa L. Paurus
    7. Kwame Attah
    8. Herbert M. Sauro
    9. Wei-Jun Qian
    10. H. Steven Wiley

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  9. H 2 O 2 sulfenylates CHE linking local infection to establishment of systemic acquired resistance

    1. Lijun Cao
    2. Heejin Yoo
    3. Tianyuan Chen
    4. Musoki Mwimba
    5. Xing Zhang
    6. Xinnian Dong

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity

  10. Coordinated regulation of photosynthesis and translation via NIK1/RPL10/LIMYB signaling module in response to biotic and abiotic stresses

    1. Ruan M. Teixeira
    2. Marco Aurélio Ferreira
    3. Otávio J.B. Brustolini
    4. Thainá F.F. Saia
    5. James Jean-Baptiste
    6. Samera S. Breves
    7. Igor N. Soares
    8. Nathalia G.A. Ribeiro
    9. Christiane E. M. Duarte
    10. Lucas L. Lima
    11. Leandro Licursi Oliveira
    12. Humberto J.O. Ramos
    13. Pedro A.B. Reis
    14. Elizabeth P. B. Fontes

    Reviewed by preLights

    1 evaluationAppears in 1 listLatest version Latest activity
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