eLife

Latest preprint reviews

1. Epigenetic Adaptation Drives Monocyte Differentiation into Microglia-Like Cells Upon Engraftment into the Central Nervous System

   This article has 18 authors:

   1. Jie Liu
   2. Fengyang Lei
   3. Bin Yan
   4. Tian Cao
   5. Naiwen Cui
   6. Jyoti Sharma
   7. Victor Correa
   8. Lara Roach
   9. Savvas Nicolaou
   10. Kristen Pitts
   11. James Chodosh
   12. Daniel E Maidana
   13. Demetrios Vavvas
   14. Milica A Margeta
   15. Huidan Zhang
   16. David Weitz
   17. Raul Mostoslavsky
   18. Eleftherios I Paschalis

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the field, as the contribution of circulating myeloid cell-derived microglia remains controversial. However, the evidence presented is inadequate as the analyses are based on a very limited set of genes, which does not sufficiently support the authors' central claims.

   Reviewed by PREreview, eLife

2. We couldn't get details of this article at this time:
   10.1101/2025.09.03.674024

3. We couldn't get details of this article at this time:
   10.1101/2025.09.13.676045

4. We couldn't get details of this article at this time:
   10.1101/2024.05.03.592470

5. We couldn't get details of this article at this time:
   10.1101/2022.03.11.483993

6. We couldn't get details of this article at this time:
   10.1101/2025.08.16.670687

7. Regulation of sensorimotor serial learning in speech production by motor compensation rather than sensory error

   This article has 6 authors:

   1. Yuhan Lu
   2. Xiaowei Tang
   3. Zhenyan Xiao
   4. Anqi Xu
   5. Junxi Chen
   6. Xing Tian

   This article has been curated by 1 group:

   • Curated by eLife

     eLife Assessment

     This study investigates how people adapt their speech when auditory feedback is altered. The analyses are rigorous and the work makes a valuable contribution by extending methods from limb motor control to speech. However, because the paradigm does not directly measure sensory error, the evidence for the proposed mechanism of sensorimotor learning is incomplete. The findings are best viewed as evidence for how prior motor adjustments influence subsequent behaviour, highlighting the need for future studies to more precisely separate sensory and motor contributions to adaptation.

   Reviewed by eLife

8. We couldn't get details of this article at this time:
   10.1101/2025.05.19.654894

9. We couldn't get details of this article at this time:
   10.1101/2025.08.26.672295

10. Early exercise disrupts a pro-repair extracellular matrix program during zebrafish fin regeneration

    This article has 5 authors:

    1. Victor M Lewis
    2. Rafael A Fernandez
    3. Samuel G Horst
    4. Carlos A Gonzalez
    5. Kryn Stankunas

    This article has been curated by 1 group:

    • Curated by eLife

      eLife Assessment

      The results in this study are useful because they begin to establish a causal link between physical activity and the cellular mechanisms of regeneration. The evidence presented is largely solid, supporting the conclusion that exercise-induced changes in the extracellular matrix disrupt regeneration; however, some claims are incomplete, requiring additional controls and a clearer distinction between the effects of mechanical loading and mechanical injury to the blastema. The work will be of interest to researchers in regenerative medicine.

    Reviewed by eLife