eLife

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1. We couldn't get details of this article at this time:
   10.1101/2021.04.26.441418

2. We couldn't get details of this article at this time:
   10.1101/2023.04.07.536075

3. Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs

   This article has 10 authors:

   1. Huiyun Lyu
   2. Guohua Yuan
   3. Xinyi Liu
   4. Xiaobo Wang
   5. Shuang Geng
   6. Tie Xia
   7. Xuyu Zhou
   8. Yinqing Li
   9. Xiaoyu Hu
   10. Yan Shi

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study presents the valuable finding that sustained calcium signaling in induced-Treg (iTreg) cells can lead to the loss of Foxp3 expression and iTreg identity by altering the chromatin landscape. The evidence supporting the claims of the authors is convincing. The work will be of interest to immunologists working on Treg cell therapy.

   Reviewed by eLife

4. Mitochondrial temperature homeostasis resists external metabolic stresses

   This article has 10 authors:

   1. Mügen Terzioglu
   2. Kristo Veeroja
   3. Toni Montonen
   4. Teemu O Ihalainen
   5. Tiina S Salminen
   6. Paule Bénit
   7. Pierre Rustin
   8. Young-Tae Chang
   9. Takeharu Nagai
   10. Howard T Jacobs

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     The study provides useful data supporting prior findings that mitochondria in cultured cells maintain a temperature that is up to 15°C above the external temperature at which cultured cells are maintained. The evidence supporting the hypothesis is solid, although direct measures of temperature in isolated mitochondria or comparison with other cellular compartments would have strengthened the ability to interpret the relevance of the findings. Nevertheless, the bioenergetic implications of the work will be of interest to cell biologists, biochemists, and physiologists.

   Reviewed by eLife

5. Gaze patterns and brain activations in humans and marmosets in the Frith-Happé theory-of-mind animation task

   This article has 5 authors:

   1. Audrey Dureux
   2. Alessandro Zanini
   3. Janahan Selvanayagam
   4. Ravi S Menon
   5. Stefan Everling

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study provides useful findings regarding the capacity for mental state attribution on the Frith-Happé task in a highly social non-human primate species, the marmoset. The methods are solid, integrating validated brain imaging and eye-tracking techniques, however, the theoretical analysis is incomplete due to the omission of a "goal-directed condition." The inclusion of the goal-directed condition would enable a stronger interpretation of the findings and would be of broad interest to neuroscientists working in social and affective sciences.

   Reviewed by eLife

6. Neural circuit mechanisms for transforming learned olfactory valences into wind-oriented movement

   This article has 8 authors:

   1. Yoshinori Aso
   2. Daichi Yamada
   3. Daniel Bushey
   4. Karen L Hibbard
   5. Megan Sammons
   6. Hideo Otsuna
   7. Yichun Shuai
   8. Toshihide Hige

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study provides important new insights into how learning affects behavior in the Drosophila model. Using a combination of connectomics, neurophysiology, and behavioral analysis, a small group of neurons in the Drosophila brain that integrates learned odor valences and promotes odor tracking by driving upwind orientation and movement is described. The study's conclusion is supported by convincing evidence and rigorous quantitative analysis. Insights from the neural circuit mechanism that translates learning-induced plasticity into appropriate behavioral actions will be of broad interest to neuroscientists.

   Reviewed by eLife

7. We couldn't get details of this article at this time:
   10.1101/2022.12.23.521749

8. Healthcare in England was affected by the COVID-19 pandemic across the pancreatic cancer pathway: A cohort study using OpenSAFELY-TPP

   This article has 14 authors:

   1. Agnieszka Lemanska
   2. Colm Andrews
   3. Louis Fisher
   4. Seb Bacon
   5. Adam E Frampton
   6. Amir Mehrkar
   7. Peter Inglesby
   8. Simon Davy
   9. Keith Roberts
   10. Praveetha Patalay
   11. Ben Goldacre
   12. Brian MacKenna
   13. The OpenSAFELY Collaborative
   14. Alex J Walker

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This study provides useful information on the impact of the pandemic on the quantity of healthcare delivered to patients with pancreatic cancer in England. The authors showed that there was no difference in the number of diagnoses of pancreatic cancer during the pandemic compared to the preceding 5-year period, but a reduction in surgical resections by nearly 25%. They reported no difference in deaths between the two periods. They show no differences in rates of diagnosis, but the clinical relevance is incomplete as they have not compared survival from cancer between those time periods.

   Reviewed by eLife

9. Epigenetic signature of human immune aging in the GESTALT study

   This article has 26 authors:

   1. Roshni Roy
   2. Pei-Lun Kuo
   3. Julián Candia
   4. Dimitra Sarantopoulou
   5. Ceereena Ubaida-Mohien
   6. Dena Hernandez
   7. Mary Kaileh
   8. Sampath Arepalli
   9. Amit Singh
   10. Arsun Bektas
   11. Jaekwan Kim
   12. Ann Z Moore
   13. Toshiko Tanaka
   14. Julia McKelvey
   15. Linda Zukley
   16. Cuong Nguyen
   17. Tonya Wallace
   18. Christopher Dunn
   19. William Wood
   20. Yulan Piao
   21. Christopher Coletta
   22. Supriyo De
   23. Jyoti Sen
   24. Nan-ping Weng
   25. Ranjan Sen
   26. Luigi Ferrucci

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This is an important study reanalysing previously published datasets to understand methylation changes during aging. The evidence supporting the conclusions is solid and sheds new light on features of aging in cells, highlighting the concept of cell-specific methylation changes and their relationship to other physiological changes such as inflammation that may impact methylation patterns. This work will be of broad interest to cell and molecular biologists.

   Reviewed by eLife

10. Decoding the genetic and chemical basis of sexual attractiveness in parasitic wasps

    This article has 4 authors:

    1. Weizhao Sun
    2. Michelle Ina Lange
    3. Jürgen Gadau
    4. Jan Buellesbach

    This article has been curated by 1 group:

    • Curated by eLife

      eLife assessment

      This important study reveals the genetic regulation of changes in cuticular hydrocarbon profiles in a Hymenopteran insect and links these changes with courtship behaviour and sexual attractiveness. It provides convincing empirical evidence, spanning genetic, chemical, and behavioural data. It adds valuable new perspectives on the mechanisms that underlie chemical recognition and communication systems in nature.

    Reviewed by eLife