Latest preprint reviews

  1. Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

    This article has 22 authors:
    1. Lampros Mavrommatis
    2. Hyun-Woo Jeong
    3. Urs Kindler
    4. Gemma Gomez-Giro
    5. Marie-Cecile Kienitz
    6. Martin Stehling
    7. Olympia E Psathaki
    8. Dagmar Zeuschner
    9. M Gabriele Bixel
    10. Dong Han
    11. Gabriela Morosan-Puopolo
    12. Daniela Gerovska
    13. Ji Hun Yang
    14. Jeong Beom Kim
    15. Marcos J Arauzo-Bravo
    16. Jens C Schwamborn
    17. Stephan A Hahn
    18. Ralf H Adams
    19. Hans R Schöler
    20. Matthias Vorgerd
    21. Beate Brand-Saberi
    22. Holm Zaehres
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The authors develop a cell culture system for studies of muscle tissue development and homeostasis. They convincingly validate a novel 3D cell model. Their thorough molecular and functional characterization will make this useful for future workers in the field.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  2. Metabolic memory of Δ9-tetrahydrocannabinol exposure in pluripotent stem cells and primordial germ cells-like cells

    This article has 7 authors:
    1. Roxane Verdikt
    2. Abigail A Armstrong
    3. Jenny Cheng
    4. Young Sun Hwang
    5. Amander T Clark
    6. Xia Yang
    7. Patrick Allard
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      The study presents valuable findings demonstrating that physiologically relevant concentrations delta-9-tetrahydrocannabinol, which is found in cannabis, have metabolic effects on early mouse embryonic cell types. The evidence supporting the claims is convincing. The work will be of interest to researchers in stem cell and epigenetics fields.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  3. Unveiling the domain-specific and RAS isoform-specific details of BRAF kinase regulation

    This article has 5 authors:
    1. Tarah Elizabeth Trebino
    2. Borna Markusic
    3. Haihan Nan
    4. Shrhea Banerjee
    5. Zhihong Wang
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This manuscript describes useful information on the interactions of the BRAF N-terminal regulatory regions (CRD, RBD and BSR) with the C-terminal kinase domain and with the upstream regulators HRAS and KRAS. The authors provide solid evidence that the BRAF BSR domain may negatively regulate RAS binding and propose that the presence of the BSR domain in BRAF provides an additional layer of autoinhibitory constraints. The data will be of interest for researchers in the RAS/RAF and general kinase regulation fields.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
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