Latest preprint reviews

  1. Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology

    This article has 3 authors:
    1. Stewart Heitmann
    2. Jamie I Vandenberg
    3. Adam P Hill
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This compelling and novel mathematical method assesses drug pro-arrhythmic cardiotoxicity by examining the electrophysiology of untreated cardiac cells. It will be valuable for future drug safety design.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
  2. Chromosome-specific maturation of the epigenome in the Drosophila male germline

    This article has 3 authors:
    1. James T Anderson
    2. Steven Henikoff
    3. Kami Ahmad
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      Using a variety of methods including mutant analyses, the authors study chromatin structure during spermatogenesis in Drosophila and transcriptional profiling in single cells/nuclei. This description of the dramatic changes in chromatin structure during spermatogenesis leads to some new observations, with convincing evidence, and it is useful for the field.

    Reviewed by eLife

    This article has 7 evaluationsAppears in 1 listLatest version Latest activity
  3. Evolution towards simplicity in bacterial small heat shock protein system

    This article has 7 authors:
    1. Piotr Karaś
    2. Klaudia Kochanowicz
    3. Marcin Pitek
    4. Przemyslaw Domanski
    5. Igor Obuchowski
    6. Barlomiej Tomiczek
    7. Krzysztof Liberek
    This article has been curated by 1 group:
    • Curated by eLife

      eLife assessment

      This valuable study advances our understanding of the evolution of protein complexes and their functions. Through convincing experimental and computational methodologies, the authors show that the specialization of protein function following gene duplication can be reversible. The work will be of interest to investigators working in biochemical evolution and those working on heat shock proteins.

    Reviewed by eLife

    This article has 8 evaluationsAppears in 1 listLatest version Latest activity
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