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  1. Universal length fluctuations of actin structures found in cells

    This article has 5 authors:
    1. Aldric Rosario
    2. Shane G McInally
    3. Predrag R Jelenkovic
    4. Bruce L Goode
    5. Jane Kondev
    This article has been curated by 1 group:
    • Curated by eLife

      eLife Assessment

      This is a theoretical analysis that gives compelling evidence that length control of bundles of actin filaments undergoing assembly and disassembly emerges even in the absence of a length control mechanism at the individual filament level. Furthermore, the length distribution should exhibit a variance that grows quadratically with the average bundle length. The experimental data are compatible with these fundamental theoretical findings, but further investigations are necessary to make the work conclusive concerning the validity of the inferences for filamentous actin structures in cells.

    Reviewed by eLife

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