eLife

Latest preprint reviews

1. We couldn't get details of this article at this time:
   10.1101/2023.12.01.569576

2. We couldn't get details of this article at this time:
   10.1101/2023.11.27.568900

3. We couldn't get details of this article at this time:
   10.1101/2023.10.17.562203

4. We couldn't get details of this article at this time:
   10.1101/2024.02.13.580128

5. We couldn't get details of this article at this time:
   10.1101/2024.01.18.576182

6. We couldn't get details of this article at this time:
   10.1101/2023.10.11.561826

7. We couldn't get details of this article at this time:
   10.1101/2024.01.24.577045

8. Single-cell RNA sequencing of iPSC-derived brain organoids reveals Treponema pallidum infection inhibiting neurodevelopment

   This article has 7 authors:

   1. Qiu-Yan Xu
   2. Yong-Jing Wang
   3. Yun He
   4. Xin-Qi Zheng
   5. Man-Li Tong
   6. Yu Lin
   7. Tian-Ci Yang

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This is a valuable study that describes the effects of T. pallidum on neural development by applying single-cell RNA sequencing to an iPSC-derived brain organoid model. The evidence supporting the claims of the authors is solid, although further evidence to understand the differences in infection rates would strengthen the conclusions of the study. In particular, the conclusions would be strengthened by validating infection efficiency as this can impact the interpretation of single-cell sequencing results, and how these metrics affect organoid size as well as comparison with additional infectious agents. Furthermore, additional functional validations of downstream effectors could be insightful.

   Reviewed by eLife

9. We couldn't get details of this article at this time:
   10.1101/2024.01.14.575448

10. We couldn't get details of this article at this time:
    10.1101/2023.12.11.571117