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   10.1101/2023.11.28.568861

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   10.1101/2024.03.20.585863

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   10.1101/2024.02.16.580657

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   10.1101/2024.02.15.580589

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   10.1101/2024.01.25.577216

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   10.1101/2024.03.21.586078

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   10.1101/2024.03.05.583572

8. Dietary bacteria control C. elegans fat content through pathways converging at phosphatidylcholine

   This article has 13 authors:

   1. Hsiao-Fen Han
   2. Shao-Fu Nien
   3. Hang-Shiang Jiang
   4. Jui-Ching Wu
   5. Chia-Yi Chiang
   6. Man-Tzu Li
   7. Leng-Jie Huang
   8. Sufeng Chiang
   9. Lien-Chieh Lin
   10. Yi-Ting Chuang
   11. Yu-Ho Lin
   12. Chao-Wen Wang
   13. Yi-Chun Wu

   This article has been curated by 1 group:

   • Curated by eLife

     eLife assessment

     This a useful study that reports a genetic regulatory network that accounts for altered lipid metabolism in response to two different bacterial diets of C. elegans. The proposed mechanism, linking vitamin B12, S-adenosyl methionine (SAM), phosphatidylcholine (PC), and neutral lipid levels, is solid but has been previously demonstrated by other studies using similar assays. The evidence to support a new layer of regulation, via the production of phospho-choline by ASM-3/acid sphingomyelinase, requires further substantiation.

   Reviewed by eLife

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   10.1101/2024.02.06.579052

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    10.1101/2024.03.13.584850